A gut sense for a microbial pattern regulates feeding - Nature A study reveals a gut–brain sensory pathway through which the microbial component flagellin activates neuropod cells in the colon to signal the brain and reduce feeding in mice.

#WeekendRead! #EveryCellIsAnImmuneCell! #TollPower! Kaelberer Bohorquez &co show @nature.com that #TLR5 signaling in response to flagellin drives neuropeptide PYY release by gut colonic neuropod cells, activating vagal neurons that signal to #brain, reducing feeding via a “neurobiotic sense”!

Toll-like receptor-mediated innate immunity against herpesviridae infection: a current perspective on viral infection signaling pathways #EBV #CMV #KSHV #HSV1 #HSV2 #VZV #HHV6 #TLR2 #TLR3 #TLR4 #TLR5 #TLR7 #TLR9

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Toll-like receptor-mediated innate immunity against herpesviridae infection: a current perspective on viral infection signaling pathways #EBV #CMV #KSHV #HSV1 #HSV2 #VZV #HHV6 #TLR2 #TLR3 #TLR4 #TLR5 #TLR7 #TLR9

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Toll-like receptor-mediated innate immunity against herpesviridae infection: a current perspective on viral infection signaling pathways #EBV #CMV #KSHV #HSV1 #HSV2 #VZV #HHV6 #TLR2 #TLR3 #TLR4 #TLR5 #TLR7 #TLR9

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How #gutbacteria evade the #immunesystem and avoid triggering inflammation: Now published in @SciImmunology, our researchers identified a new #flagellin that binds to the #immunereceptor #TLR5 without inducing a pro-inflammatory response. Read more:...