#arterialstiffness hashtag - Bluesky

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

2 months ago

This review highlights #VascularAging and #ArterialStiffness as key drivers of #CardiovascularDisease, detailing structural and functional changes, end‑organ damage, measurement methods, and prevention/therapy strategies.

#OpenAccess in #STTT: doi.org/10.1038/s413...

1 0 0 0

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

4 months ago

#Hyperlipidemia activates C/EBPβ to drive #VSMCs toward a macrophage-like phenotype, promoting #ArterialStiffness, while C/EBPβ loss alleviates #VascularRemodeling and identifies PDGF-CC as a potential #biomarker of human arterial stiffness.

#STTT: doi.org/10.1038/s413...

0 0 0 0

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

4 months ago

This review explores #VascularAging and #ArterialStiffness as key drivers of #CVD, detailing structural and functional changes, #EndOrganDamage, measurement methods, and emerging therapeutic targets for interdisciplinary translational research.

#STTT: doi.org/10.1038/s413...

0 0 0 0

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

5 months ago

Summarizing the pathophysiology underlying #VascularAging & #ArterialStiffness, the resulting end-organ damage and methods for measuring arterial stiffness, with highlights on preventive & therapeutic strategies and future directions. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

1 0 0 0

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

7 months ago

This study provides molecular insights into how C/EBPβ activation in #hyperlipidemia induces the phenotypic transition of contractile VSMCs to macrophage-like cells and promotes #ArterialStiffness. #medsky

#STTT #OpenAccess article here: doi.org/10.1038/s413...

0 0 0 0

Signal Transduction and Targeted Therapy

@sigtrans-sttt.bsky.social

7 months ago

This review outlines the mechanisms of #VascularAging & #ArterialStiffness, their effects on end-organ damage, measurement techniques, potential preventive & therapeutic strategies, and future directions for research. #CVD #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

0 0 0 0

RichardJR

@electricbluesfan.bsky.social

7 months ago

3/12 Researchers measured pulse wave velocity (PWV)—how fast blood moves through arteries. Stiffer vessels mean faster PWV and older 'vascular age.'

All COVID groups showed significantly higher PWV than controls, indicating accelerated aging.
#PulseWaveVelocity #ArterialStiffness

0 0 1 0

Hao Yin

@haoyin.bsky.social

8 months ago

Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use Author(s): Mohammadi, Leila; Navabzadeh, Mina; Jiménez-Téllez, Nerea; Han, Daniel D; Reagan, Emma; Naughton, Jordan; Zhou, Lylybell Y; Almeida, Rahul; Castaneda, Leslie M; Abdelaal, Shadi A; Park, Kat...

Chronic (>1 yr) #Cannabis smoking or THC eating is associated with #EndothelialDysfunction
⏬ #FlowMediatedDilation

#BloodPressure #ArterialStiffness unaffected

N=55 healthy non-tobacco smokers/vapers
29 smokers
9 eaters
26 nonusers

#JAMACardio 2025
jamanetwork.com/journals/jam...

5 1 0 0

@arxivlens.bsky.social

9 months ago

Central and Brachial Pressures: Effects on Arterial Stiffness in Older Adults
Cole, M., Gepner, A. D. et al.
Paper
Details
#ArterialStiffness #OlderAdultHealth #CardiovascularResearch

0 0 0 0

@arxivlens.bsky.social

9 months ago

Novel markers of inflammation associate with blood pressure and artery stiffness
Beilin, L. J., Mangoni, A. A. et al.
Paper
Details
#InflammationMarkers #BloodPressure #ArterialStiffness

0 0 0 0

Hao Yin

@haoyin.bsky.social

10 months ago

Understanding Thoracic Aortic Disease in Women

♀️➡️3-fold⏫risk of Dissection/Rupture of aneurysmal aortas
♀️➡️40% more likely aortic death

Estrogen
#VascularAging
#ArterialStiffness
Pregnancy & TAD

#AortaEd
#CircRes 2025 @ahajournals.bsky.social
www.ahajournals.org/doi/10.1161/...

7 2 0 0

American Journal of Preventive Cardiology

@ajpcardio.bsky.social

11 months ago

🆕 Just published in AJPC!
Association Between Arterial Stiffness and MASLD in U.S. Young Adults
📊 Using NHANES 2005–2018 data, this study highlights a key link between metabolic liver disease and vascular health in youth.

📖 ow.ly/jnsP50VN3TA

#MASLD #ArterialStiffness #CardioSky #MedSky

2 3 0 0

Hao Yin

@haoyin.bsky.social

1 year ago

How are #EndothelialDysfunction & #ArterialStiffness are coupled in #vascularAging ?👇

Biomechanical #Aging of Aortas of eNOS -/+ -/- 🐭
1.5~12-mo
Beyond Press+Flow

Wall geometry + matrix architecture
Biaxial Active + passive mechanics

#AJPHeartCirc 2025
journals.physiology.org/doi/abs/10.1...

4 0 0 0

KStenhouse🇨🇦

@klstenhouse.bsky.social

1 year ago

“Key factor in anoxic neuronal death.”

More on #TRPM7, which unlike #TRPM6, is heavily expressed in #neural cells.

💡

I believe these variants are very likely expressed in some #pwMS as well. Not causative, as spasticity. Do you have #MultipleSclerosis #MS #highbloodpressure #arterialstiffness?

pmc.ncbi.nlm.nih.gov/articles/PMC...

1 0 0 0

Hao Yin

@haoyin.bsky.social

1 year ago

If interested in SMC EZH2 #ArterialStiffness #VascularAging, read another recent paper from Iris Jaffe Lab #CardiovascularResearch 2022

Smooth muscle mineralocorticoid receptor as an epigenetic regulator of vascular ageing

academic.oup.com/cardiovascre...

2 1 0 0

TRAstonDrs

@castltrastondrs.bsky.social

1 year ago

Arterial stiffness as a novel tool for the early prediction of preeclampsia: a perspective - Journal of Human Hypertension Journal of Human Hypertension - Arterial stiffness as a novel tool for the early prediction of preeclampsia: a perspective

#MedSky🧪 #Obgyn #Hypertension #Publichealth #CardioSky This brief perspective highlights the current state of first-trimester #preeclampsia prediction & #arterialstiffness www.nature.com/articles/s41...