JCI - Effect of external cues on clock-driven protection from influenza A infection

Ilucidating the critical interplay between environmental timing cues and endogenous #CircadianRhythms for #Influenza outcomes www.jci.org/articles/vie... @sengupta_shaon #ImmuneResponse #Chronobiology #CircadianMedicine #TranslationalScience

TRR 418 - Foundations of Circadian Medicine TRR 418 – Foundations of Circadian Medicine is looking for PhD students and postdoctoral researchers who are eager to push boundaries and help pioneer a new era of circadian clock-based diagnostics an...

See the joint job posting for all consortium projects www.circadianmedicine.de, visit our lab website buchauer-lab.eu, and apply by August 8th.

#trr418 #circadianmedicine

ML uncovers 24h rhythms in cancer 🕒🧬
Using COFE ☕, we reconstruct #circadian rhythms from human tumor biopsies across 11 #cancer types!
Turns out, tumor #clocks tick in a different timezone 🕰️💊
Got data? Let’s connect! 🤝
#AIforHealth #CircadianMedicine #oncology

Insightful talk by Dr Kramer - time for #CircadianMedicine - Mission , Motivation & Approach.
HairTime, a novel assay that estimates #chronotype from a single hair sample could be used in future for diagnosing #disorders like #DSWPD in #adolescents. #SleepSky

www.researchgate.net/publication/...

#Sleep/ #CircadianMedicine #seminars :-

#Current Topics in #Visual & #Circadian #Neuroscience (Spring/summer 2025) -

Previous recordings - youtube.com/playlist?lis...

#SleepMedicine #sleepsky #webinar #seminar #circadianHealth #circadianRhythms

🚀 Thrilled to collaborate on this study led by Jihwan Myung, where we explored why organisms prefer #networks of autonomous #clocks over a single central #oscillator, proposing enhanced robustness, specialization, and adaptability.

👉 buff.ly/xhMsboJ

🙏 @dfg.de
#circadian #circadianmedicine

A synthetic chronogenetic gene circuit for programmed circadian drug delivery | Nature Communications Circadian medicine, the delivery of therapeutic interventions based on an individual’s daily rhythms, has shown improved efficacy and reduced side-effects for various treatments. Rheumatoid arthritis and other inflammatory diseases are characterized by diurnal changes in cytokines, leading to inflammatory flares, with peak disease activity in the early morning. Using a combination of synthetic biology and tissue engineering, we developed circadian-based gene circuits, termed “chronogenetics”, that express a prescribed transgene downstream of the core clock gene promoter, Period2 (Per2). Gene circuits were transduced into induced pluripotent stem cells that were tissue-engineered into cartilage constructs. Our anti-inflammatory chronogenetic constructs produced therapeutic concentrations of interleukin-1 receptor antagonist in vitro. Once implanted in vivo, the constructs expressed circadian rhythms and entrained to daily light cycles, producing daily increases in biologic drug at the p

Unlock better rheumatoid arthritis treatment with new chronogenetic circuits! Combines synthetic biology & tissue engineering for timed drug delivery. #CircadianMedicine PMID:39920119, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-56584-5 #Medsky #Pharmsky #RNAsky 🧪

20 March @esrs.bsky.social #circadianMedicine
#circadian
#esrs #srs #researchSleep
#sleepResearchSociety
#webinar #sleepmedicineEducation
#sleepHealth
#sleepMedicine

#GoodLightGoodSleep #SLRCH
#CircadianMedicine
#CircadianRhytms #GoodLightGoodSleep #SLRCH
#Sleepmedicine
#SleepHealth
#CircadianHealth

... In #ICU settings - considering #circadian state modulation as a treatment, through interventions in the patient’s environmental conditions or using #melatonin, to improve #circadianRhythms , could enhance the patients’ #cardiovascular variables & expedite recovery....
#CircadianMedicine

Prevalence of Circadian Rhythm Sleep-Wake Disorders and Associated Factors in Euthymic Patients with Bipolar Disorder Recent studies have suggested that there are certain pathophysiological relationships between bipolar disorder (BD) and circadian rhythm dysfunction. However, apparently no studies have clarified the ...

...the presence of #CRSWD - #Circadian Rhythm sleep-wake disorders was significantly associated with younger onset age of #BipolarDisorder & family history of suicide. The prevalence of CRSWD could be quite high in BD patients.
journals.plos.org/plosone/arti...
#SleepMedicine #circadianMedicine

Does anyone know of a #CircadianMedicine #StarterPack? #circadian #chronobiology #ChronoTherapy