🎆 Happy new year and our first 2026 issue is out!
Cover: #epiblast development

👉Perspective: biological clocks
👉Review: #mitosis #CellDeath #inflammation
🔬 #chromatin #cancer #Bcells #Tcells #autophagy #organoids #mechanobiology #TranscriptionFactors #Xist & more!

www.nature.com/ncb/volumes/...

A human epiblast model reveals dynamic TGFβ-mediated control of epithelial identity during mammalian epiblast development - Nature Cell Biology The authors optimize an in vitro human epiblast model, which they utilize to show that early TGFβ family inhibition prevents epithelial identity, whereas it is dispensable after epithelium formation. ...

🥂Congratulations to @grazianomartello.bsky.social & co: they optimize an in vitro human #epiblast model, which they use to show that early #TGFβ family inhibition prevents epithelial identity, while it is dispensable after epithelium formation.
👉https://rdcu.be/eVPMa

www.nature.com/articles/s41...

A human epiblast model reveals dynamic TGFβ-mediated control of epithelial identity during mammalian epiblast development - Nature Cell Biology The authors optimize an in vitro human epiblast model, which they utilize to show that early TGFβ family inhibition prevents epithelial identity, whereas it is dispensable after epithelium formation. ...

☕The authors optimize an in vitro human #epiblast model, which they utilize to show that early #TGFβ family inhibition prevents epithelial identity, while it is dispensable after epithelium formation. @grazianomartello.bsky.social
👉https://rdcu.be/eVPMa
bit.ly/4pNo2xL

New study identifies N-myristoyltransferase (NMT) as a novel regulator of pluripotency, with distinct roles in mice and humans. #stemcells #epiblast #pluripotency ow.ly/IJYb50WNONG

@isscr.org @cellpress.bsky.social @gairdnerawards.bsky.social @sickkidsvs.bsky.social

Distinct pathways drive anterior hypoblast specification in the implanting human embryo - Nature Cell Biology Weatherbee, Weberling, Gantner et al. find contrasting requirements for BMP in the anterior signalling centre and pre-implantation epiblast between mice and humans. They further find that NOTCH may be...

#NCB2024
In March, @zernickagoetz.bsky.social & co found contrasting requirements for BMP in the anterior signaling center and pre-implantation #epiblast between mice and humans; and that NOTCH may be indispensable for human epiblast survival.
www.nature.com/articles/s41...