Between 2.4 and 4.1 million people estimated to be living with chronic #hepatitis B #infection in #Europe ...
| #HBV | #microbiology | #hepatitisB | #virus | #pathogen | By @ecdc.europa.eu via @eurekalert.bsky.social
FAM151A inhibits hepatitis B virus by modulating cccDNA transcriptional activity
FAM151A emerges as a novel host factor that suppresses #HBV replication by inhibiting #cccDNA transcriptional activity without reducing its abundance, offering fresh insight into #antiviral strategies against persistent HBV infection.
#OpenAccess: doi.org/10.1016/j.ge...
New research article
Classification and sequencing of #hepatitis D virus from a large cohort of chronically infected individuals paired with co-infecting hepatitis B virus sequencing: a genomic characterisation study
www.thelancet.com/journals/lan...
#IDSky #ClinMicro #ViroSky #HDV #HBV #OA
Genotype switching in hepatitis B virus may increase the risk of vertical transmission from mother to child, highlighting an important factor in HBV transmission dynamics.
doi.org/10.1016/j.dc...
#HepatitisB #HBV #GenotypeSwitching #VerticalTransmission #MotherToChildTransmission
CXCR5+CD8+ T cells in chronic #HBV exhibit effector and B-cell helper functions with preserved #cytokine production despite PD-1 expression, inversely correlating with viral load and highlighting their potential in enhancing #AntiviralImmunity.
#OpenAccess: doi.org/10.1016/j.ge...
📑 Isolated anti‑HBc is the most durable marker of prior HBV infection after HBsAg loss, but it’s not always benign. It may signal resolved infection, occult HBV, or reactivation risk during immunosuppression.
➡️ https://ow.ly/xc3Q50YAOLR
🏷️ #HBV #LiverDisease 🫧#PearlsfromthePros
Our article on #PeerSupport in #HBV is a #TopCitedArticle published by J.Viral Hep in 2024. Great to know support growing for patient voice, #coproduction of #HealthCare & lived experience.
#NoHep #MedSky #LiverSky #hepatitis 🧪
@cnwl.nhs.uk @wiley.com @uclnews.bsky.social
doi.org/10.1111/jvh....
Findings underscore the importance of continued HBV prevention, including vaccination, to protect blood donors and the wider community.
onlinelibrary.wiley.com/doi/abs/10.1...
#BloodSafety #HepatitisD #HBV #GlobalHealth #Research #Cameroon
Liebe Kolleginnen und Kollegen,
Bitte Gesundheituntersuchung mit Screening auf #HBV und #HCV anbieten.
Tatsächlich scheint es Kollegen und Kolleginnen zu geben nicht wissen das man diese präventiv Laborleistung ohne Budgetbelastung machen kann.
#aids #aidstageberlin
In honour of @ahmedelsharkawy.bsky.social, a colleague, collaborator & friend for 25 yrs, and a wise, knowledgeable, & dedicated doctor working in support of patient voice.
Sadly missed but his legacy continues. #HBV #MedSky #LiverSky @easlnews.bsky.social
britishlivertrust.org.uk/a-tribute-to...
Genotype switching in hepatitis B virus as a potential risk for vertical transmission from mother-to-child was first reported
This study reports #HBV #MTCT despite reduced maternal viral loads & infant #immunoprophylaxis, showing #ViralLoad is key but not the sole factor; genotype switching and #quasispecies diversity reveal added mechanisms in transmission. #PublicHealth
#OpenAccess: doi.org/10.1016/j.dc...
Steatosis Paradox:
Unraveling Pathways of Suppressive Effect of Hepatic #Steatosis on #Hepatitis B Virus
www.sciencedirect.com/science/arti... #OpenAccess #HBV #MicroSky #MedSky
Viral genotype changes can influence transmission pathways. Research on hepatitis B virus genotype switching highlights implications for vertical transmission and infection risk.
doi.org/10.1016/j.dc...
#HepatitisB #ViralGenomics #GenotypeSwitching #MotherToChildTransmission #HBV
Very proud to release this work! - huge collaboration to assess #HBV #epidemiology ( #infection & #immunity) in a large population study in #SouthAfrica. High prevalence, high #treatment need, low #vaccine mediated protection.
@crick.ac.uk @uclnews.bsky.social @ahri-news.bsky.social
🧪 #MedSky
Doch erst so jung? 😊 Dachte der Zusammenschluss von #HBV (Handel, Banken und Versicherungen) und #ÖTV (Öffentliche Dienste, Transport und Verkehr) liegt länger zurück. 🤦, zu dem was man zur Zeit an verschiedenen Stellen an Äußerungen wegen dem #Warnstreik liest.
Is Hepatitis B more dangerous than HIV? Compare the infectiousness, mortality rates, and health risks of HBV and HIV. Learn which virus is harder to kill and how to protect yourself.
mrmed-6851.freshlearn.com/blog/14303
#HealthAwareness #HIV #HepatitisB #HBV #SexualHealth #LiverHealth
Hepatic Viral Reservoirs in Concurrent #HIV and #HBV: From Mechanistic Insight to Integrated Cure Strategies www.dovepress.com/hepatic-vira... (open access review)
📊 CHB patients on Peg-IFN:
✅ HBsAg decline at wk24 & baseline HBsAg best predict functional cure.
✅ HBV RNA & HBeAg levels (wk12/24) best predict HBeAg loss.
Guiding personalized therapy.
👥 @HenryEChang@asianliverctr
#Hepatology #HBV #LiverTwitter
👉 www.xiahepublishing.com/2310-8819/JC...
Lots of learning & dialogue about how we strengthen equitable North-South partnerships, gain from bilateral capacity building, improve community co-design & invest in skills exchange for #HBV #hepatitis #research. 🧪
@ice-hbv.bsky.social @who.int @sdgactioncampaign.org
#MedSky #LiverSky #elimination
Genotype switching in hepatitis B virus highlights how viral genetic variation may influence mother-to-child transmission dynamics.
doi.org/10.1016/j.dc...
#HepatitisB #ViralGenomics #GenotypeSwitching #MotherToChildTransmission #HBV
#MASLD and #HBV overlap tackled in this article - lots of questions remaining in how to assess and treat this emerging dual threat to global #liver health 🧪
#MedSKy #LiverSky #HepSky #hepatitis
hepatologyforum.org/article/257
Excellent work led by Ricky Sinharay showing cost-effectiveness of expanding #HBV treatment, which supports scale-up to reduce complications & mortality 🧪
@england.nhs.uk @royalberkshospital.bsky.social @easlnews.bsky.social @who.int
#LiverSky #MedSky #hepatitis #BASL
fg.bmj.com/content/earl...
British Association for Study of the #Liver discussion on #treatment & #cancer #surveillance for people living with #HBV - we should treat all who need surveillance, but surveillance not necessary for all on treatment. Important to unify clinical & public health approaches. 🧪 #BASL #BVHG #LiverSky
Among patients with #HIV, standardized protocols are necessary to ensure #HBV screening occurs before initiating antiretroviral therapy regimens that lack anti-HBV activity, including long-acting cabotegravir plus rilpivirine.
Read More: https://bit.ly/4r33FO2
Predicting PEG-IFN response in hepatitis B: HBsAg decline at week 24 best predicts functional cure. For HBeAg loss, HBV RNA & HBeAg levels at week 12 are key. Better markers = tailored therapy. #HBV #HepatitisB #LiverTwitter
Promising findings by Hiroshima University researchers. In chronic #HepatitisB #HepB, #HBV #RNA may better predict #livercancer risk than current markers, even when viral DNA is undetectable. This could help identify patients who need closer monitoring earlier. www.linkedin.com/posts/drmelv...
#Nedsky🧪 #IDsky #pedsky #immunosky #publichealth @jama.com #HBV vaccination has substantially ⏬️ HBV-related morbidity & mortality.Infants infected with HBV in the first year of life have a 90% risk of developing chronic infection, which is associated with chronic #liverdisease
This study reports rare #HBV #MothertoChild transmission despite low maternal viral load & neonatal #immunoprophylaxis, revealing genotype switching & quasispecies diversity, underscoring mechanisms beyond #viralload.
#IDSky #EpiSky #ImmunoSky
#OpenAccess: doi.org/10.1016/j.dc...
#HepatitisBvirus core protein stability is sustained by host factor PSME1, which prevents HBc degradation via the #26Sproteasome; silencing PSME1 reduces HBc levels & HBV transcription, identifying PSME1 as a novel #biomarker for chronic #HBV.
#OpenAccess: doi.org/10.1016/j.ge...
A novel innovative virus-hunter #vaccine demonstrated the ability to actively capture viruses and overcome the tolerogenic immune microenvironment that is present with #HepatitisB virus infection.
#HBV #HepatitisBVirus
