Taste The Rainbow 🩸
#lab #pbt #mlt #mls #blood #labweek #vampires #horror #bloodbank #heme

Stripe patterns in blood cells offer new clues for diagnosing disorders and understanding natural designs Stripe patterns are commonly seen in nature—for instance, birds and fish move in coordinated flocks and schools, fingerprints form unique designs, and zebras can be identified by their distinctive str...

Stripe patterns in blood cells offer new clues for diagnosing disorders and understanding natural designs
#biology #cells #heme #blood #micro

Share your challenging cases and contribute to discussion with leading experts. De-identified cases presented during live sessions offer an opportunity for diverse #clinical perspectives.

🌐You can submit your own cases for the upcoming sessions at hemehub.org/case-submiss...

#Heme #MedEd #HemeHub

Great work (and a lot of work) from lead author Lewis. Thanks to all for putting up with me during my stay. Thanks to the University of Adelaide for letting me go for a productive visit to explore #heme #enzyme #catalysis, #crystals and #structures.

HMOX1 controls a heme/ferritin switch that protects cells from ferroptosis Modulating the intracellular labile iron pool (LIP) has emerged as a promising strategy to induce ferroptosis in cancer cells, offering a way to overcome resistance to apoptosis-based therapies. One o...

(1) New preprint from our lab!
HMOX1 controls a heme/ferritin switch that protects cells from ferroptosis.
Loss of HMOX1 stabilizes heme, boosts ferritin, and suppresses ferroptotic death.
👉 doi.org/10.1101/2025...
#ferroptosis #heme #ironmetabolism #preprint

Novel blood test for chronic fatigue achieves 96% accuracy Scientists at the University of East Anglia and Oxford Biodynamics have developed a high accuracy blood test to diagnose chronic fatigue syndrome, also known as myalgic encephalomyelitis (ME/CFS).

A new blood test demonstrates 96% accuracy in diagnosing myalgic encephalomyelitis/chronic fatigue syndrome, offering a potential advance in reliable identification and management of the condition.
#medsky #news #fatigue #myalgia #blood #bloodtests #heme #ME #CFS #covid #genetics #cancer #EpiSwitch

Great how interdisciplinary work reveal details on #enzymes regarding mechanism and application. A little #heme #protein is a versatile #biocatalyst ... and here we show the interplay of heme with a tyrosine embedded in a proton network facilitates the rare enantioselective Meinwald Rearrangement in

What could cause the reactivation of Epstein–Barr virus in individuals with long COVID Published in Emerging Microbes & Infections (Vol. 14, No. 1, 2025)

What could cause the reactivation of Epstein–Barr virus in individuals with long COVID

Heme results in the reactivation of EBV. AGS-Bx1-ACE2 cells were infected by the SARS-CoV-2 prototype strain (MOI = 1) (a–f)

#Heme #EBV #ViralReactivation #LongCOVID

Heme-based sulfide sensing in bacteria: A new target for antibiotics Heme binding to a bacterial transcription factor is critical for hydrogen sulfide (H2S) signaling, report researchers from Japan. Heme binding promotes the reaction of H2S with the transcription…

A new target for #antibiotics ...

| #Heme | #bacteria | #hydrogensulfide | #H2S | #pathogens | Via @sciencex.bsky.social

AI is designing proteins that could help treat cancer A team used generative AI to enhance T cells’ ability to fight melanoma. The immunotherapy approach needs more testing before use in cancer patients.

AI designer proteins supercharge T cells' ability to target and destroy melanoma cells.

#medsky #cancer #research #protein #ai #news #science #immune-cells #cytology #blood #heme #biomedical #t-cells #nobel #chem #onco #rf-diffusion

Plant-Based Diet and Risk of Iron-deficiency Anemia. A Review of the Current Evidence and Implications for Preventive Strategies - Current Nutrition Reports Purpose of Review This review provides a comprehensive overview of iron metabolism, emphasizing the influence of dietary patterns—particularly vegetarian and vegan diets—on iron status and associated ...

The potential link btwn red #meat consumption & #cancer may be partially mediated by the high intake of #heme iron. Vegetarian & #vegan diets often surpass the #iron intake of omnivorous #diets. Well-planned #plantbased diets can be nutritionally adequate: doi.org/10.1007/s136... #nutrition #health

We are excited to introduce HemeHub, an educational platform dedicated to advancing hematology knowledge. Follow us for expert-led case discussions, conference highlights, and evidence-based resources designed for healthcare professionals.

#Hematology #MedEd #Heme #BloodDisorders #MedicalUpdates

24th International Conference on Cytochrome P450

24th ICCP450 meeting June to 4th July 2025 30 at @unibe.ch is being generously supported by a grant to @pandeylab.bsky.social by 🙏
@snsf.ch #SNSF #Switzerland. 🌍Join us in Bern. Register: iccp450bern.unibe.ch #Science #Heme #CytochromeP450 #P450

Dissecting NO Association and Dissociation Dynamics of Myoglobin, Hemoglobin, and Heme-Model Compounds | Inorganic Chemistry pubs.acs.org/doi/10.1021/... Coletta, Ascenzi, and co-workers @InorgChem #iron #NO #heme #myoglobin #hemoglobin #ferrous #nitrosylation

In summary, the Practical Anemia Bundle for SusTained Blood Recovery (PABST-BR) improves Hb recovery in predominantly post-surgical critical illness. Now, we need to see if that translates to improvements in outcomes that matter to patients.

#emimcc #ansky #heme

#Cytochrome #NitrogenCycle #Spectroscopy #Catalysis #Heme #Haem #NitrousOxide #Hydroxylamine #Greenhouse #ProteinResearch #ScientificReview #Biochemistry #MolecularBiology #ProteinStructure #LifeSciences #ResearchInnovation #ScienceCommunity #AcademicPublishing #ProteinFunction

Proud to share the work of my forst ever PhD student and first author of this paper @dylanduerre.bsky.social!! Here, he summarizes it perfectly! #brownfat #metabolism #BCAA #heme @uwmadison.bsky.social @uofutahcihd.bsky.social

Divesiran Is Tolerable and Shows Positive Early Signals in Polycythemia Vera The siRNA divesiran was well-tolerated and reduced the number of phlebotomies that were required in patients with polycythemia vera.

Divesiran Is Tolerable and Shows Positive Early Signals in Polycythemia Vera
#heme #oncology #MedEd
www.onclive.com/view/divesir...

How Staphylococcus aureus 'steals' iron from our blood during infections Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin—a process crucial to their survival during infections. Using a novel time-resolved X-ray solution scattering (...

How #Staphylococcus aureus 'steals' #iron from our #blood during infections.

#kleptophagy #kleptoparasitism #heme

phys.org/news/2025-02...

Orca-T Is a Safe Addition to HSCT-RIC in Advanced Hematologic Malignancies Orca-T with HSCT-RIC displayed robust and early donor myeloid and T-cell engraftment in patients with advanced hematologic malignancies.

Orca-T Is a Safe Addition to HSCT-RIC in Advanced Hematologic Malignancies
@astct.bsky.social #TANDEM25 #heme #oncology
www.onclive.com/view/orca-t-...

FDA Awards RMAT Designation to NXC-201 for Relapsed/Refractory AL Amyloidosis The designation underscores the potential of the CAR T-cell therapy NXC-201 to serve as a new option in relapsed/refractory AL amyloidosis.

DA Awards RMAT Designation to NXC-201 for Relapsed/Refractory AL Amyloidosis
@fda.gov #oncology #heme
www.onclive.com/view/fda-awa...

Meaning of #heme pigment.. heme

MB-105 Receives Orphan Drug Designation in Relapsed/Refractory CD5+ T-Cell Lymphoma The FDA has granted orphan drug designation to the CAR T-cell therapy MB-105 in CD5-positive T-cell lymphoma.

MB-105 Receives Orphan Drug Designation in Relapsed/Refractory CD5+ T-Cell Lymphoma
@fda.gov #heme #MedEd #lymsm
www.onclive.com/view/mb-105-...

Significado de #heme pigmento.. heme

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells Vertebrate heme synthesis requires three substrates: succinyl-CoA, which regenerates in the tricarboxylic acid cycle, iron and glycine. For each heme molecule synthesized, one atom of iron and eight m...

research article [2017]:

Extracellular glycine is necessary for optimal hemoglobinization of erythroid cells
pmc.ncbi.nlm.nih.gov/articles/PMC...

"Vertebrate heme synthesis requires three substrates: succinyl-CoA..., iron and glycine."

#biology #biochemistry #heme #RBCs #glycine #anemia

If the US is leaving the WHO can we all just agree to use ICC? 🤣 #heme #hemepath #unity

Buy your copy today!

Significado de #heme pigmento.. heme

Second-Line Ropeginterferon Alfa-2b Boosts Responses in Essential Thrombocythemia Ropeginterferon alfa-2b improved responses in patients with essential thrombocythemia with resistance or intolerance to hydroxyurea.

Second-Line Ropeginterferon Alfa-2b Boosts Responses in Essential Thrombocythemia #heme #oncology www.onclive.com/view/second-...

You have to engage patients where they are at. Listen. Figure out what the problem is, in their own words. From there, you can explore solutions collaboratively starting from a safe place.

#Ansky #emimcc #transfusion #heme #shareddecisionmaking

Just drove a group of teenagers home, quietly listening like a seasoned dad, and I swear to god they were spontaneously talking about the ABO blood grouping system... #transfusion #heme #Ansky