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Protein and genomic language models uncover the unexplored diversity of bacterial immunity The bacterial pangenome contains a vast diversity of antiphage systems, whose overall extent is still unknown. In this study, we developed complementary machine learning approaches to systematically p...

www.science.org/doi/10.1126/...

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Protein and genomic language models uncover the unexplored diversity of bacterial immunity The bacterial pangenome contains a vast diversity of antiphage systems, whose overall extent is still unknown. In this study, we developed complementary machine learning approaches to systematically p...

#microsky #phagesky #phage defence

www.science.org/doi/10.1126/...

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Scientists are working on “everything vaccines” Scientists are developing broad-spectrum vaccines that could protect against multiple virus families by targeting more conserved areas of pathogens and also better-training the body’s innate immune…

#Scientists are working on “everything vaccines” ...

| #vaccine | #microsky | #infections | #diseases | #pathogens | Via @economist.com

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#MicroSky

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#Medsky🧪 #IDsky #episky #microsky #pedsky #immunosky #publichealth #Vaccinesmatter Vaccination prevents an estimated 4.5 mil deaths annually and has saved approximately 154 mil lives since the expanded programme on immunisation began over 50 years ago

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Eastern Utah measles infections double within a week, health officials say Health officials have confirmed a doubling of measles cases in Daggett, Duchesne and Uintah counties in the past week.

Eastern #Utah #measles #infections double within a week ...

| #virus | #microsky | #pathogen | #publichealth | Via @ksl.com

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Post-translational modifications of GlmR integrate metabolic and stress signals to maintain cell envelope homeostasis in Bacillus subtilis Author summary Bacteria must integrate feedback from multiple metabolic processes and environmental cues to efficiently allocate carbon to produce essential building blocks such as nucleotides, amino ...

journals.plos.org/plosgenetics...

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Soil microbial diversity associates with lower prevalence of human bacterial pathogens across global soils Soil-inhabiting pathogens threaten human health, but their biogeography and associations with soil biodiversity remain poorly understood. Here, we pre…

www.sciencedirect.com/science/arti...

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#MicroSky #PhageSky

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Gut bacteria may influence social behavior through smell In a new study, Northwestern University neurobiologists discovered that gut bacteria and the nose work together to shape social behavior in mice, including who fights and who backs down. Using a…

#Gut #bacteria may influence social behavior through #smell ...

| #microbes | #microsky | #neurobiology | #microbiome | Via @sciencex.bsky.social

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The paper for my tool, SCCmecExtractor is now up on bioRxiv. Highly recommend taking a look if you are interested in SCCmec and want to obtain these elements from whole genome sequences. It also does gene level typing of mec and ccr, even if extraction isn’t possible.

#microsky #AMR

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Congratulations to our I2SysBio researchers Alba Arévalo-Lalanne, Paola Corbín-Agustí, Javier Buceta @javierbuceta.bsky.social, Juli Peretó @julipereto.bsky.social and their collaborators, for their study about genetic engineering of gut commensal Bifidobacterium animalis 👏
#microsky
#biotechnology

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#Daphnia #limnology #plankton #freshwater #hostmicrobiota #hostmicrobe #microbialecology #symbiosis #microbeinteractions #hostmicrobeecology @microbiomevif.bsky.social #holobiont #SymbioSky #MicroSky #microbiomesky #Microbiology @hostmicrobelit.bsky.social

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Organoid models for infectious diseases Editors welcome the submission of primary research Articles focusing on recent advances of stem cell-based organoid models for studying infectious diseases, ...

#CallForPapers! 📣 @commsbio.nature.com and @natcomms.nature.com are seeking primary research articles from authors who use stem cell-based #organoid models for studying #InfectiousDisease.

Submit by December 21!

www.nature.com/collections/...

#assembloid #stemcell #IDsky #Virosky #Microsky

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Bacterial-like vaccine cues could help extend immunity against evolving viruses Researchers at the University of Wisconsin School of Veterinary Medicine have identified a possible way to make longer-lasting vaccines for respiratory viruses like influenza and the coronavirus that…

#Bacterial-like #vaccine cues could help extend #immunity against evolving #viruses ...

| #respiratory | #microsky | #pathogens | #infections | Via @sciencex.bsky.social

medicalxpress.com/news/2026-03...

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#Soil microbial diversity associates with lower prevalence of human bacterial pathogens across global soils.

Global soil metagenomes show human pathogens thrive in wet croplands & rise as biodiversity falls under global change.

www.sciencedirect.com/science/arti... #microbiota #MicroSky

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Microbial Community Characterization in Semi-Hydroponic Systems of Starbor Kale (Brassica oleracea L.) Grown Under Normal Gravity & Simulated Microgravity.

Kale grown in coco coir under varied #gravity shows distinct microbial shifts & enzyme profiles
www.sciencedirect.com/science/arti... #MicroSky

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The Ixodes ricinus complex life cycle comprises four life stages (egg, larva, nymph and adult), where each post-egg stage needs a blood meal to develop into the next stage or reproduce. Larvae and nymphs feed on many vertebrate species, including mammals, songbirds and lizards, whereas adults feed on a narrower range of hosts, most commonly deer. Lyme borreliae are not passed from infected female ticks to their offspring; thus, the bacteria are maintained in an enzootic cycle between immature ticks (larvae and nymphs) and reservoir hosts, typically small mammals and songbirds. 
For illustrative purposes, this figure typifies the life cycle of Ixodes scapularis in the northeastern USA. Eggs are laid in the late spring; larvae will hatch in mid-summer and then seek their first host in late summer. Engorged larvae will detach, drop off the host and moult into nymphs. Unfed nymphs emerge and quest for their second host the following late spring through summer, which is therefore the epidemiologically most risky time of the year. Engorged nymphs detach, drop off the host and moult into adults in the leaf litter. Beginning in the fall, adult ticks quest for a third host, most commonly deer. Engorged females detach from the host and drop into the leaf litter, where they overwinter. Adult ticks that are unable to locate hosts in the fall will also overwinter and resume questing in early spring. Fed I. scapularis females will oviposit an egg mass (up to 1,500–2,000 eggs), and then die. Although both nymphs and adult females may be infected, because of their small size (about the size of a poppy seed), their large numbers, and a spring/summer activity period that coincides with increased outdoor human activity, nymphs are responsible for most human infections. Because they are larger (about the size of a sesame seed) and have red coloration, adult female ticks are easier to notice and remove before the bacteria can be transmitted

The Ixodes ricinus complex life cycle comprises four life stages (egg, larva, nymph and adult), where each post-egg stage needs a blood meal to develop into the next stage or reproduce. Larvae and nymphs feed on many vertebrate species, including mammals, songbirds and lizards, whereas adults feed on a narrower range of hosts, most commonly deer. Lyme borreliae are not passed from infected female ticks to their offspring; thus, the bacteria are maintained in an enzootic cycle between immature ticks (larvae and nymphs) and reservoir hosts, typically small mammals and songbirds. For illustrative purposes, this figure typifies the life cycle of Ixodes scapularis in the northeastern USA. Eggs are laid in the late spring; larvae will hatch in mid-summer and then seek their first host in late summer. Engorged larvae will detach, drop off the host and moult into nymphs. Unfed nymphs emerge and quest for their second host the following late spring through summer, which is therefore the epidemiologically most risky time of the year. Engorged nymphs detach, drop off the host and moult into adults in the leaf litter. Beginning in the fall, adult ticks quest for a third host, most commonly deer. Engorged females detach from the host and drop into the leaf litter, where they overwinter. Adult ticks that are unable to locate hosts in the fall will also overwinter and resume questing in early spring. Fed I. scapularis females will oviposit an egg mass (up to 1,500–2,000 eggs), and then die. Although both nymphs and adult females may be infected, because of their small size (about the size of a poppy seed), their large numbers, and a spring/summer activity period that coincides with increased outdoor human activity, nymphs are responsible for most human infections. Because they are larger (about the size of a sesame seed) and have red coloration, adult female ticks are easier to notice and remove before the bacteria can be transmitted

Lyme Borreliosis

Nature Reviews Disease Primers
pubmed.ncbi.nlm.nih.gov/41888159/

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#TickSky

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SimCells successfully target and kill drug-resistant bacteria We are continually in an evolutionary arms race with bacteria. As we develop new antibiotics, they develop resistance, and so it goes on until some of our treatments no longer work. Superbugs and…

SimCells successfully target and kill #drug-resistant #bacteria ...

| #DrugResistance | #MicroSky | #antibiotics | #Superbugs | #AMR | Via @sciencex.bsky.social

phys.org/news/2026-03...

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The Landscape and Regulatory Determinants of A-to-I RNA Editing in Escherichia coli and Pseudomonas aeruginosa Isolated From Patients With Urinary Tract and Ear Infections Here, we describe the occurrence, regulatory features, and predicted effect of RNA-specific sequence changes resulting from A-to-I RNA editing in E. coli a

doi.org/10.1093/infd... A to I editing in clinical isolates during infection 💫🦠 #UTI #microsky #rnasky

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Presentation at a scientific conference

Presentation at a scientific conference

Had two great days at the KNVM/NVMM Spring Meeting! 🌷

I had the honour to present our work on a synthetic community of the infant gut, expanding on our previous effort led by Nancy Ioannou (doi.org/10.1093/isme...) 🦠

Looking back on two days of lovely talks and conversations! 👩‍🔬

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It’s always fun to look at phenotypic microbial diversity on an agar plate. #microsky

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One day left to apply! #microsky

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MicrobeAtlas unifies more than two million microbiome samples in a single resource, harmonized to facilitate discoveries across technologies.

MicrobeAtlas unifies more than two million microbiome samples in a single resource, harmonized to facilitate discoveries across technologies.

A new paper in 𝐂𝐞𝐥𝐥 presents MicrobeAtlas, a harmonised resource built from more than 2 million microbiome samples. It reveals recurring community patterns, geographic preferences and broad trends across microbial ecosystems. Congrats to @tsbschm.bsky.social #Microbiome #microsky
📰 buff.ly/PsNS9ML

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1.7 million pounds of dried dairy powder recalled nationwide due to salmonella risk: FDA TOPEKA (KSNT) – Federal health officials report that thousands of pounds of a dairy powder product is being voluntarily recalled nationwide as it may be contaminated with salmonella. The Food and D…

1.7 million pounds of dried #dairy #powder recalled nationwide due to #salmonella risk ...

| #recall | #microsky | #bacteria | #contamination | Via ksnt .com

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Great week for #Klebsiella papers - what happens to an ST that is long-time associated in a hospital? See what Allan Zuza found out in the course of his masters (!!!), outstanding work 😊
#MicroSky #IDSky #MedSky 💻🧬 in #MGen @microbiologysociety.org
www.microbiologyresearch.org/content/jour...

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The PhageExpressionAtlas just made it to bioRxiv. Visually explore the transcriptomes of phage-host interactions or harness the database for analysis across infections! Please leave feedback, which functionalities/data you find missing.
Preprint:
www.biorxiv.org/content/10.6...

#phagesky #microsky

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