American Physiology Summit The American Physiology Summit is the premier event for physiologists and life science researchers. Network, share discoveries, and advance your career.

Later this week, the American #Physiology Summit 2026 kicks off in Minneapolis, MN (April 23–26)! This will be an exciting #conference, gathering leading experts and educators to discuss the latest advances in physiology research.

buff.ly/jrXGbET

#APS2026 #Metabolism #Respirometry

Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells - Nature Metabolism This study demonstrates that overexpression of irisin, an exercise-induced myokine, ameliorates obesity and insulin resistance in high-fat-diet-fed mice by increasing local IL-33 production and…

#Irisin, an #exercise-induced #myokine, counters #obesity via effects on #adipose tissue — but how? With help from Promethion #Metabolic Cages, a Nature #Metabolism study has shown that irisin modulates adipose #IL33 levels to increase #thermogenesis and reduce fat content.

#METPHYS - The Metabolic Physiology Meeting The Metabolic Physiology Meeting 2024 overview, speakers, agenda, hotel reservation and registration information. #metphys2024

Less than 2 weeks to go until #METPHYS2026 (Apr 27–30) — we're looking forward to speaking with leading scientists about the latest research in #metabolic #physiology! This is the FINAL CALL to register if you haven't already.

buff.ly/WBRNjvU

#Metabolism #Respirometry #IndirectCalorimetry

American Physiology Summit The American Physiology Summit is the premier event for physiologists and life science researchers. Network, share discoveries, and advance your career.

Just 2 weeks to go until the American #Physiology Summit 2026 (April 23–26, Minneapolis, MN)! This lively and engaging event is a highlight of the annual #conference calendar. Check out the webpage for the full program and registration.

buff.ly/M7QMw1U

#APS2026 #Metabolism #Respirometry

Dapagliflozin regulates autophagy in nephropathy associated with non-diabetic obesity via elevated plasma β-hydroxybutyrate levels Abstract. Obesity is a major contributor to chronic kidney disease, accounting for approximately 20%–25% of cases globally. In obesity-related kidney disease (OKD), ectopic lipid accumulation in…

#Dapagliflozin, a #SGLT-2 inhibitor, could help to treat #obesity-related #kidney disease — a recent study using Sable Promethion #Metabolic cages has shown how the drug increases plasma β-hydroxybutyrate levels to effect #renoprotection.

buff.ly/vLi2Jx3

#Metabolism #Respirometry #CKD #Diabetes

The Expert Approach to Preclinical Indirect Calorimetry Experiments - InsideScientific Join us to explore the IICCC’s standardized guidelines for preclinical indirect calorimetry, focusing on rigorous data normalization techniques and the integration of multi-modal physiological…

How can you best apply the International #IndirectCalorimetry Consensus Committee's (IICCC) standardized guidelines to your experiments? Learn from Alexander Banks, PhD, Associate Professor of Medicine and Chairman of the IICCC, in our #OnDemand #webinar.

buff.ly/2oInqi1

#Respirometry #Metabolism

An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice Chronic elevations in interleukin-6 (IL6) signaling have been shown to exacerbate features of cardiometabolic disease. A common variant in the IL6 promoter (location -174 G/C, identifier rs1800795) is...

How do genetic variants of #interleukin-6 (#IL6) contribute to #cardiometabolic disease? With help from Sable Promethion #Metabolic Cages, scientists tested a knock-in mouse model of the IL6 promoter variant #rs1800795.

buff.ly/GDBusEN

#Respirometry #Metabolism #Inflammation #Adipose #CVD #HFD

Less than 1 month to go until the American #Physiology Summit 2026 (April 23-26, Minneapolis, MN)! This #conference will bring together thousands of researchers, educators, and students to explore the biggest topics in the field.

buff.ly/F3A0UGu

#Conference #Metabolism #Metabolic #Respirometry

#METPHYS - The Metabolic Physiology Meeting The Metabolic Physiology Meeting 2024 overview, speakers, agenda, hotel reservation and registration information. #metphys2024

Last call to register for #METPHYS2026 -- The #Metabolic #Physiology Meeting 2026 (April 27-30, 2026)! Join leading researchers at the beautiful Sonesta Resort, Hilton Head Island, SC, USA to discuss the latest advances in the field.

buff.ly/djLXeU7

#Conference #Metabolism

#GPNMB is a key #biomarker of #metabolic disorders — but what is its role in adaptation to #obesogenic diets? With help from a FoxBox #Respirometry System, scientists showed that GPNMB inactivation disrupts diurnal #hepatic glycogen #metabolism.

buff.ly/OcRp6jb

#Obesity

Gut-Brain Axis | Keystone Symposia Join us at the Keystone Symposia on Gut-Brain Axis, March 2026, in Breckenridge, with field leaders!

Next week — Keystone Symposia #conference on #Diabetes and the #GutBrain Axis (Mar 16–19) in CO, USA! Experts from #neuroscience, #gutbiology, #metabolism, #nutrition, and #pharmacology will discuss the latest research & therapeutic applications.

buff.ly/cugH7ab

#Respirometry #NutrientSensing

Could the #cannabinoids #cannabidiol (#CBD) and #cannabigerol (#CBG) help to treat metabolic dysfunction-associated steatotic #liver disease (#MASLD)? With help from Promethion #Metabolic Cages, scientists combined metabolic, #metabolomics & #lipidomics data to find out.

buff.ly/6UNAVor

#Steatosis

Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression - Cell Death Discovery Cell Death Discovery - Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression

How does the #cytokine #Lipocalin-2 (#LCN2) link #bone and #EnergyHomeostasis? With help from Sable Promethion #Metabolic Cages, scientists revealed how LCN2 modulates bone remodeling by driving #ferroptosis & suppressing #Wnt signaling.

buff.ly/uMp5AmZ

#SLC22A17 #IndirectCalorimetry #Respirometry

Adipocyte NADH dehydrogenase reverses circadian and diet-induced metabolic syndrome - Nature Metabolism Circadian clock in adipocytes maintains metabolic health by regulating mitochondrial complex I respiration.

How does #Circadian dysregulation contribute to #metabolic diseases? With help from Promethion Metabolic Cages, a Nature #Metabolism study has shown how clock dysfunction alters Complex I respiration, impairing #adipocyte oxidative metabolism.

buff.ly/lw6L3R7

#IndirectCalorimetry #Respirometry

Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia Shi et al. delineate an interplay among tumor cells, immune cells, and the nervous system that drives cancer cachexia and anorexia. Specifically, tumor-derived CSF1 induces macrophage GDF15, which…

#Cachexia is a dangerous & difficult-to-treat #wasting of muscle and fat induced by #cancer. With help from Promethion Core #Metabolic Cages, scientists identified a novel #tumor-#immune-#neural circuit & disrupted it to relieve cachexia in mice.

buff.ly/MPmanAc

#GDF15

Sable Systems International (@sablesystems.bsky.social) Sable Systems International: Trusted, reliable, & precise instrumentation for metabolic and animal behavior measurement founded by Dr. John Lighton (@sablesys.bsky.social).

Do you use 🦋 #Bluesky? We invite you to follow our new ✨ Sable Systems International ✨ channel for updates on #metabolic #physiology research, upcoming #conferences & events, expert #webinars, and much more!

buff.ly/nMmxkST

#Metabolism #IndirectCalorimetry #Respirometry #ByScientistsForScientists

UNLV Health Sciences Research Symposium UNLV Health Sciences Research Symposium

Less than 2 weeks until the UNLV Health Sciences Research Symposium (Feb 27) at the University of Nevada, Las Vegas! This promises to be a great day of cross-disciplinary dialogue between experts from across the health sciences.

buff.ly/z1rSZJz

#HealthScience #Metabolism #Physiology #Conference

Linking energy metabolism and echolocation: the relationship between basal metabolic rate and peak frequency in bats Echolocation is a sensory adaptation that enables bats to navigate and forage in darkness, and its energetic demands may influence their basal metabolic rate (BMR). Peak frequency is the frequency ...

#Echolocation enables remarkable feats of nocturnal foraging in bats — but how does peak echolocation frequency influence #BMR across #bat species? With help from a FoxBox #Respirometry System, scientists combined original & existing data to investigate.

UNLV Health Sciences Research Symposium UNLV Health Sciences Research Symposium

Just 3 weeks to go until the UNLV Health Sciences Research Symposium at the University of Nevada, Las Vegas (Feb 27)! Are you going? We'll be there — come say hi!

buff.ly/XwzzNQx

#Metabolism #Respirometry #IndirectCalorimetry