A striking result from this study is Figure 6. Male offspring of calorie-restricted mothers show increased sexual behaviour and reduced aggression despite being fed normally themselves.
biorxiv.org/content/10.6...
#Epigenetics #Transgenerational #CalorieRestriction #Neuroscience

A large, new evidence review finds intermittent fasting may not help overweight or obese patients loose a significant amount of weight or improve their quality of life.

youtu.be/i_TxVWun2Ys

#IntermittentFasting #WeightLossResearch #DietTrends #ObesityTreatment #CalorieRestriction

Support by grants from Fondazione Telethon, the Italian Ministry of Health, and the Italian Ministry of University and Research (Investment PE8 –Project Age-It: “Ageing Well in an Ageing Society”, National Recovery and Resilience Plan).

#ADTKD #UMOD #calorierestriction #RareKidneyDisease

Planning the research for 2026 with myself, Jim Penman (CEO of Epigenes) and Garrie Arumugam, our major collaborator at La Trobe University. #calorierestriction #intermittentfasting

Long-term calorie restriction may slow biological aging in the brain A new study suggests that restricting calorie intake over a lifetime may slow the biological aging of support cells in the primate brain. The research provides evidence that a thirty percent reduction...

Long-term calorie restriction may slow biological aging in the brain #Science #HealthandMedicine #Nutrition #CalorieRestriction #AgingResearch #BrainHealth

Long-term calorie restriction may slow normal brain aging – BioNews Central A study using a human-related model found that reducing calorie intake by 30 percent for over 20 years can slow brain aging. ...

A study using a human-related model found that reducing #CalorieIntake by 30 percent for over 20 years can slow #BrainAging. 
#Aging #BrainHealth #Diet #CalorieRestriction

📢 New in #IJBNPA! A recent publication examines whether energy expenditure from #PhysicalActivity can influence the benefits of #CalorieRestriction
🔗 Read more:
ijbnpa.biomedcentral.com/articles/10.1186/s12966-...

What happens when eating 1500 calories daily for weight loss? Expected results, safety considerations, and meal planning for sustainable success! #1500CalorieDiet #WeightLossResults #CalorieRestriction

fitfusiohub.com/what-happens-if-you-only...

Exploring ADPKD treatments: Can reducing calories help control hereditary kidney disease? A patient's experience with an ADPKD treatment trial focusing on calorie reduction to manage hereditary kidney disease.

We’re proud to spotlight the groundbreaking work of Drs. Kristen Nowak & Katharina Hopp, whose research is shaping the future of ADPKD care. Read the full story:
www.uchealth.org/today/explor...
🔬 #ADPKD #KidneyResearch #UCHealth #CalorieRestriction #MedicalInnovation #CUKidney

Discover 1500-calorie diet results! Learn what happens when you eat 1500 calories daily, expected weight loss, benefits, and potential side effects. #1500CalorieDiet #CalorieRestriction #WeightLossResults

fitfusiohub.com/what-happens-if-you-only...

Calorie restriction can help animals live longer. What about humans? Living comes with a side effect: aging. Despite what you might hear on social media or in advertisements, there are no drugs that are known to slow or reverse human aging. But there’s some evidence...

Calorie restriction can help animals live longer. What about humans? #Science #HealthandMedicine #PublicHealth #CalorieRestriction #LongevityResearch #HealthScience

Anti-ageing drug rapamycin may extend life almost as effectively as restricting calories – our new research
#Health #Rapamycin #AntiAgeing #Longevity #DietMimics #CalorieRestriction #LifeExtension #AgeingResearch #Metformin #HealthSpan #ScientificResearch
the-14.com/anti-ageing-...

Intermittent fasting comparable to traditional diets for weight loss – BioNews Central A systematic review and meta-analysis found that intermittent fasting and continuous calorie restriction have similar effects on weight loss and heart health, but longer studies are needed to confirm these findings. ...

A #SystematicReview and #MetaAnalysis found that #IntermittentFasting and continuous #CalorieRestriction have similar effects on #WeightLoss and #HeartHealth, but longer studies are needed to confirm these findings.
#Diet #Fasting

Is a Hypocaloric Diet Safe and Effective for Long-Term Health? A hypocaloric diet, defined by reduced calorie intake below daily energy expenditure, promotes weight loss and improves metabolic markers such as insulin sensitivity and lipid profiles. Evidence also ...

Is a Hypocaloric Diet Safe and Effective for Long-Term Health? www.news-medical.net/health/Is-a-... #Hypocaloric #WeightLoss #MetabolicHealth #Calories #CardiovascularHealth #Longevity #Nutrition #CalorieRestriction

Frontiers | Less is more: calorie restriction as a therapeutic for mental health disorders Anxiety, depression, and substance use disorders are prevalent mental health disorders that have debilitating health outcomes, and current treatment options ...

Calorie restriction enhances brain health and extends lifespan; it may also help alleviate anxiety and depression. Our review explores the science behind this idea and how we might harness it to create new treatments. #calorierestriction #MentalHealth www.frontiersin.org/journals/psy...

After 4 years of groundwork, Epigenes has officially launched from our new labs at La Trobe University. Exciting times ahead as we advance new drugs that mimic the mental health benefits of calorie restriction #mentalhealth #calorierestriction #Epigenetics

#CalorieRestriction #VascularAging #Progeroid🐭

CR (30%⏬, 7- to 22-wk) in ERCC1Δ/−🐭 rescues #AorticAging
⏬elastin breaks
⏬proteoglycan
⏬MMPSense680
⏬ssDNA-cGAS-STING1
⏬inflamm VCAM1+ or LGALS3+ #SmoothMuscleCell

+Aortic bulk RNAseq

#Aging_Cell 2025
onlinelibrary.wiley.com/doi/10.1111/...

Impact of Parental Time-Restricted Feeding on Offspring Metabolic Phenotypic Traits

Please to share my first paper on calorie restriction (intermittent fasting; IF) with new collaborator Thirum Arumugam. We show that the metabolic benefits of IF can be inherited. www.ijbs.com/v21p1852.htm #calorierestriction #epigenetics #intermittentfasting

Cells use signaling to respond to changes, like IGF-1 (growth), mTORC1 (protein synthesis), and AMPK (energy sensing). Calorie restriction reduces IGF-1 and mTORC1 while activating AMPK, limiting tumor growth. Learn more at www.cancereducation.net

#CancerEducation #CalorieRestriction #CellSignaling

Calorie restriction offers potential anti-cancer benefits, but it's essential to check your BMI first to ensure it's safe. Use online tools to calculate BMI and BMR, and consult your doctor before starting. Learn more at www.cancereducation.net.

#CancerEducation #CalorieRestriction #CancerDiet #BMI

Professor Terry Johns | Distinguished medical research in Brain Cancer & Epigenetics Explore the groundbreaking work of Professor Terry Johns in the field of Brain Cancer & Epigenetics. Discover his distinguished contributions to medical research, offering new insights into understand...

I’ve been thinking about creating a personal website for a while and decided it’s time! It highlights my brain cancer research alongside my behavioral studies. Excited to share my journey and new research directions! #epigenetics #braincancer #CalorieRestriction www.terrancejohns.com

Lithocholic acid enhances health and lifespan, mimicking calorie restriction Lithocholic acid (LCA), a metabolite induced by calorie restriction (CR), activates AMPK and mimics anti-aging benefits. A recent study highlights LCA's role in improving muscle performance, glucose t...

Lithocholic acid enhances health and lifespan, mimicking calorie restriction ✨🧬💪 news-medical.net/news/2025010... #Longevity #AntiAging #CalorieRestriction #Health #AMPKActivation #Metabolomics #Muscle #LifeExtension #Science #LCA @natureportfolio.bsky.social

Dietary interventions improve mitochondrial function and reduce inflammation in obesity Study demonstrates that dietary interventions such as calorie restriction, intermittent fasting, and ketogenic diet improve mitochondrial function in monocytes and reduce inflammation in obesity by mo...

Dietary interventions improve mitochondrial function and reduce inflammation in obesity 🥗🧬🔥 www.news-medical.net/news/2024072... #Diet #Mitochondria #Health #Obesity #GutMicrobiota #CalorieRestriction #IntermittentFasting #KetogenicDiet #Inflammation #Nutrition #Bioenergetics #Health

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomi...

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss 🥗⚖️🦠 www.news-medical.net/news/2024060... #IntermittentFasting #ProteinPacing #GutHealth #WeightLoss #MetabolicHealth #NutritionScience #CalorieRestriction #Microbiome @natureportfolio.bsky.social