#Macrophage anti-bacterial activity is controlled by adenylate kinase 4–mediated mitochondrial DNA synthesis. New study from Wei-Yao Chin, Shi-Chuen Miaw et al. (National Taiwan University): rupress.org/jem/article/...
#InnateImmunity #inflammation #InfectiousDisease #HostDefense #Mitochondria
Poster deadline is approaching for @keystoneSymposia.bsky.social #InnateImmunity: Diversity in #HostDefense & Disease, this March in Banff! See scholarship, abstract and registration: keysym.us/KSInnateImmune26 #KSInnateImmune26 @jkagan1.bsky.social @brozlab.bsky.social
Mucosal immune responses are central to host defense, disease prevention, and treatment, linking barrier immunity with systemic inflammatory control.
doi.org/10.1038/s413...
#MucosalImmunity #HostDefense #ImmuneHomeostasis #DiseasePrevention
Still a chance to register for @keystonesymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March in Banff!
Our @embojournal.org subject editor Ioannis Papaioannou is looking forward to joining you there!
#KSInnateImmune26
hubs.la/Q03TCrHw0
Join us for the upcoming innate immunity keystone. There’s a great lineup of speakers.
@keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March!
keysym.us/KSInnateImmune26 #KSInnateImmune26
Deadlines are approaching for @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March in Banff! See key dates: keysym.us/KSInnateImmune26 #KSInnateImmune26
Tried #HostDefense #Mushroom 🍄🟫
samples on sale and I have
been loving them!! Tried the mocha the other day and it tasted so good! Today I tried the matcha🍵
You don't taste the
mushroom, just tastes like a drink.🍄🟫 #Vegan #VeganFood #VeganTreats #Matcha #Mocha #Mushrooms #Coffee #Cocoa #Fungi 🍄🟫
Submit your poster abstract until Feb 19 for @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March in Banff! See abstract and reg dates: hubs.la/Q03TCrHw0 #KSInnateImmune26 @embojournal.org
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #InnateImmunity: Diversity in #HostDefense & Disease, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #InnateImmunity: Diversity in #HostDefense & Disease, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
Transcription of #HIV-1 is heterogenous among authentic latent CD4+ T cell clones, say Cintia Bittar, Michel C. Nussenzweig @rockefeller.edu and colleagues: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Virology
Working with a great team to organize @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March! Join us to explore emerging research in Banff! keysym.us/KSInnateImmune26 #KSInnateImmune26
Antibiotic use in early life impairs MAIT cell–mediated immunity in adulthood, say Gabrielle LeBlanc, Adam Sobel, Michael Constantinides (@mikerobe.bsky.social) and colleagues @scripps.edu: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #MucosalImmunology #LymphocyteBiology #Microbiome
Hi Folks! Interesting reading comparing mushroom #mycelium vs mushroom fruit body extracts. 🍄
Repost from Elan Sudberg:
The team behind Alkemist Labs long time friend and client, Paul Stamets / #HostDefense just posted a mechanistic paper on #Lion’sMane ( #Hericiumerinaceus ) mycelium...
1/7
Rhodehouse, Siliciano @jhu.edu and colleagues show that, in a nonhuman primate (NHP) model, natural control can be nearly as effective as antiretroviral therapy in controlling viral replication. rupress.org/jem/article/...
#Virology #LymphocyteBiology #InfectiousDisease #HostDefense
Does fever drive the #evolution of antiviral genes? A new Perspective by Ryan Langlois @langloislab.bsky.social: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Virology
Autoantibodies neutralizing type I IFNs in a fatal case of #H5N1 avian #influenza. New study from Qian Zhang, Jean-Laurent Casanova @casanovalab.bsky.social @rockefeller.edu and colleagues: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #SARSCoV2
Dynamics of natural and pharmacologic control of an SIV variant with an envelope trafficking defect. New study from Kyle Rhodehouse, Robert F. Siliciano @jhu.edu and colleagues: rupress.org/jem/article/...
#Virology #LymphocyteBiology #InfectiousDisease #HostDefense
(2/2) They are found to underlie a growing range of severe infections of emerging and circulating viruses, including seasonal influenza viruses and SARS-CoV-2. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #SARSCoV2 #Influenza
(2/2) They are found to underlie a growing range of severe infections of emerging and circulating viruses, including seasonal influenza viruses and SARS-CoV-2. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #SARSCoV2 #Influenza
pDCs amplify tissue-resident memory CD8⁺ T cell responses during viral reinfection, say Elena Hernández-García, Salvador Iborra and colleagues (Universidad Complutense de Madrid): rupress.org/jem/article/...
#InfectiousDisease #HostDefense #MucosalImmunology
SLC7A8 is essential for metabolic fitness and function of Th2 cells, say Santosh Panda, Marco Colonna and colleagues @washumedicine.bsky.social: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Inflammation #MucosalImmunology #Helminths #Allergies
Panda et al. of the Colonna lab identify SLC7A8 as a Th2-specific amino acid transporter essential for Th2 proliferation, cytokine production, and type 2 immunity. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Inflammation #MucosalImmunology #Helminths #Allergies
Heterologous mucosal vaccine boosting enhances mucosal and systemic immunity by distinct mechanisms, say Cameron Bissett, Teresa Lambe and colleagues @ovg.ox.ac.uk: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #MucosalImmunology #SARSCoV2 #COVID19
Herpesvirus CNS infections in genetically heterozygous - transcriptionally homozygous IRF7 deficiency. New study from Marvin Werner, Trine Mogensen and colleagues @au.dk: rupress.org/jem/article/...
#HumanDiseaseGenetics #Immunodeficiency #InfectiousDisease #HostDefense #InbornErrorsOfImmunity
Sphingolipid sensor degrades cGAMP to suppress antiviral host defense- #virus #lipids #hostdefense #innateImmunity
www.cell.com/immunity/ful...
Cameron Bissett, Teresa Lambe et al. @ovg.ox.ac.uk demonstrate that mucosal delivery of heterologous omicron #vaccine is able to overcome deleterious prime-derived immunological imprinting via multiple mechanisms. rupress.org/jem/article/...
#InfectiousDisease #HostDefense #SARSCoV2 #COVID19
Werner, Mogensen et al. @au.dk identify genetically heterozygous and transcriptionally homozygous deficiency of IRF7 as an inborn error of interferon immunity underlying #herpesvirus CNS infection. rupress.org/jem/article/...
#HumanDiseaseGenetics #Immunodeficiency #InfectiousDisease #HostDefense
👉 Host-targeted immunity meets antibiotic synergy!
We show that OM-89 reprograms bladder epithelial cells to boost their lysosomal activity and antibiotic uptake, helping clear intracellular UPEC.
📖 Read more: www.biorxiv.org/content/10.1...
#UTI #InfectiousDisease #HostDefense #Organoids #UTIsky
Lung tissue-resident memory T cells optimize protection by IL-10 regulation of #InnateImmunity, say Alexander Yang, Donna Farber and colleagues @columbiamed.bsky.social: rupress.org/jem/article/...
#inflammation #MucosalImmunology #InfectiousDisease #HostDefense
