In our latest episode, we chat with Dr. Mansour Haeryfar (@haeryfar.bsky.social at Western University about all things #MAITCells!🎙️

We dive deep into the therapeutic potential of these cells across a range of conditions.

🎧 Listen now: https://bit.ly/4sYIflI

CD4+ mucosal-associated invariant T cells express highly diverse T cell receptors Abstract. Mucosal-associated invariant T (MAIT) cells are highly conserved innate-like T cells in mammals recognized for their high baseline frequency in h

We are pleased to share our new publication linking TRAV1-2 negative MAIT cells, CD4 coexpression, and tuberculosis. A conserved innate-like T cell subset with more TCR diversity than previously appreciated. academic.oup.com/jimmunol/adv... #Immunology #maitcells #TCRdiversity

Kaiwen Zhu, Yan Lu, André Veillette et al. @ircm.bsky.social show that the interplay between CD2 and its ligands is pivotal for #MAITcell development and activation, highlighting potential approaches for treating human diseases implicating #MAITcells. rupress.org/jem/article/...

CD2 and its ligands are involved in development and activation of #MAITcells, say Kaiwen Zhu, Yan Lu, André Veillette et al. @ircm.bsky.social rupress.org/jem/article/...

#InnateImmunity #LymphocyteBiology

Development and Functions of MAIT Cells Mucosal-associated invariant T (MAIT) cells are evolutionarily conserved T cells that recognize microbial metabolites. They are abundant in humans and conserved during mammalian evolution, which sugge...

Development and Functions of MAIT Cells
#MAITcells #unconventionalTcells

www.annualreviews.org/content/jour...

Research Article

Analysis of Gut-Homing Receptors in Circulating Mucosal-Associated Invariant T Cells and Their Presence in Synovial Tissue From Patients With Axial Spondyloarthritis

📖 www.jrheum.org/cgi/content/...

#axialspondyloarthritis #gut #MAITcells #synovium

Unlocking the potential of unconventional T cells The cutting edge of cancer research is now expanding beyond conventional T cells to a less-explored, unconventional, unique subset of T cell: mucosal-associated invariant T (MAIT) cells. Engineered MA...

The cutting edge of #CancerResearch is now expanding beyond conventional #Tcells to a less-explored, unconventional, unique subset of T cell: mucosal-associated invariant T (MAIT) cells. Engineered #MAITcells may stand to change future #AllogeneicTreatments for solid tumors. 🧪🧬⑂

Polyunsaturated fatty acid-induced metabolic exhaustion and ferroptosis impair the anti-tumour function of MAIT cells in MASLD Mucosal-associated invariant T (MAIT) cells constitute a highly abundant innate-like T cell population in the human liver that is critical for immune surveillance of hepatic cancers but often dysfunct...

9/ 📖 Read more: www.journal-of-hepatology.eu/article/S016...

@easlnews.bsky.social @jhepatology.bsky.social @cd1mr1.bsky.social
#Immunometabolism #MAITcells #LiverImmunology #Ferroptosis #MASLD #HCC #LipidPeroxidation #TcellDysfunction #CancerImmunotherapy #TumorMicroenvironment #FattyLiver

Congratulations to Juan Carlos Lopez (@lopix8.bsky.social) for winning the #BioLegend Workshop Prize at #WIRM2025! 🎉 We are honored to see our work on #MAITcells contributing to the field of #Allergy. Excited for what’s to come!

Followed by Juan Carlos Lopez (@lopix8.bsky.social) who shared our latest insights on the role of MAIT cells in Th2 inflammation.
#Allergy #MAITcells #Immunology

Later that day, Juan Carlos Lopez (@lopix8.bsky.social) will talk about our most recent findings on the role of MAIT cells in Th2 inflammation.
#Allergy #MAITcells #Immunology

#MAITcells #Tcells #CARTcells #liverimmunology #MR1 #cancer #immunometabolism #Tcellengineering #immunotherapy #immuneoncology

New CD1MR1 Immunology Society is launching with a webinar series on December 3rd, 3pm - 4pm (UTC+1). I'm delighted to be talking about #MAITcells at the first one along with @barrallab.bsky.social (iNKTs)
Forward your email & I'll send to S.A.B to be added to the mailing list for the zoom links

Delighted for continued support from Health Research Board Ireland for our Obesity Immunology Research work - we are investigating the impact of low iron on #MAITcells #NKcells and #CD8+Tcells

Splendid talk @VeronikaBosak on #MAITcells IL-26 and Crohn's disease. Patients data combined with mucosal organoids. Great support @gmatteoli1978 group. @FNUSA_ICRC @IHBTcelltherapy @MyeInfoBank … the presentation hattrick of @FricLab at @CSAC_CZ conference.