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New article to read! #Collagen and #microvascular alterations contribute to #neuromuscular degeneration and disease progression in chronic #intestinal pseudo-obstruction.

➡️ Novel mechanistic insights into disease pathophysiology.

🔗 doi.org/10.1111/joim.70078

#CIPO

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Kim Muczynski, MD, PhD - Kidney Microvascular Endothelium HLA-DR Confers Peripheral T cell Tolerance
Kim Muczynski, MD, PhD - Kidney Microvascular Endothelium HLA-DR Confers Peripheral T cell Tolerance YouTube video by University of Washington Division of Nephrology

Dr. Kimberly A. Muczynski discusses her prolific research in Human Kidney Immunology. #nephsky #research #kidney #t-cells #microvascular #meded @uwmedicine.bsky.social

Watch: youtu.be/6tMaASv1PBk

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Greater awareness is the first step toward meaningful progress.

Myth: Coronary Microvascular Disease is rare.

Fact: Coronary Microvascular Disease is increasingly recognized as a common contributor to angina and ischemia, yet remains underdiagnosed.

#CMD #Microvascular

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#longcovid #postcovid #covid #microcirculation #viralinfection #endothelialdysfunction #imedos #health #vasculardiagnostics #cardiovascular #vascular #biomarkers #cardiology #healthtech #innovation… |... 𝗜𝗺𝗲𝗱𝗼𝘀 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗿𝗲𝘃𝗲𝗮𝗹𝘀 𝗽𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝘁 𝗺𝗶𝗰𝗿𝗼𝘃𝗮𝘀𝗰𝘂𝗹𝗮𝗿 𝗲𝗻𝗱𝗼𝘁𝗵𝗲𝗹𝗶𝗮𝗹 𝗱𝘆𝘀𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝗽𝗼𝘀𝘁-𝗖𝗢𝗩𝗜𝗗 𝘀𝘆𝗻𝗱𝗿𝗼𝗺𝗲 A highly regarded and still highly relevant study demonstrates that retinal vessel analysis provides ...

𝗜𝗺𝗲𝗱𝗼𝘀 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆 𝗿𝗲𝘃𝗲𝗮𝗹𝘀 𝗽𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝘁 #microvascular 𝗲𝗻𝗱𝗼𝘁𝗵𝗲𝗹𝗶𝗮𝗹 𝗱𝘆𝘀𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻 𝗶𝗻 𝗽𝗼𝘀𝘁-𝗖𝗢𝗩𝗜𝗗 𝘀𝘆𝗻𝗱𝗿𝗼𝗺𝗲

A well-established study highlights our vascular parameters as clinical biomarkers, offering insights into prolonged symptoms.

tinyurl.com/DVA-LongCOVID

#Covid #LongCovid #Microcirculation #Cardio

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Head & neck surgeons, what if your microscope is the bottleneck? See why Dr. Huang of @bcmhouston chose #MyVeo and Evolved ARveo 8 for his practice performing daily #microvascular reconstructions. Watch now to see what stood out above all others? 👉 https://fcld.ly/dto4d5a

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New on bioRxiv! 🚨
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8

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🎉#Congrats to Nethika Ariyasinghe, JP Amoakon & Prof. Naren from @cedarssinai.bsky.social on their new @cp-starprotocols.bsky.social @cellpress.bsky.social paper: Live-cell Ca²⁺ #imaging in a human lung #microvascular vessel on a chip model built on the ibidi µ Slide VI 0.4

🔗https://zurl.co/q1XjU

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Higher baseline uric acid levels at the time of #T1D diagnosis in individuals aged 15–34 years are linked to future #macro- and #microvascular complications #Diabetes #DiabetesResearch

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MRI investigation of #cardiovascular function and LV myocardial perfusion in patients with #sepsis and #septicshock, in initial recovery and 1-2 months later, shows that #myocardium #microvascular integrity is not affected in the short term.
doi.org/10.14814/phy...
#Infection #Cardiac

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Unsupervised Unfolded rPCA Enhances Ultrasound Microvascular Imaging

Unsupervised Unfolded rPCA Enhances Ultrasound Microvascular Imaging

U2‑rPCA, an unsupervised deep‑learning filter, boosts ultrasound microvascular image contrast, improving CNR by 2–10 dB without labeled data. Read more: getnews.me/unsupervised-unfolded-rp... #ultrasound #microvascular

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Coronary microvascular disease in women: epidemiology, mechanisms, evaluation, and treatment Coronary microvascular dysfunction (CMD) involves functional or structural abnormalities of the coronary microvasculature resulting in dysregulation of coronary blood flow (CBF) in response to myocard...

#Coronary #microvascular #disease in #women:

Epidemiology, mechanisms, evaluation and treatment

#CMD #MVS #MVA 🫀
#Vasomotor #dysfunction
#Endothelium #dependent #independent
#CFR #IMR #MPRI
#ACh #provocation #testing
#INOCA #MINOCA #ANOCA #NOCAD

cdnsciencepub.com/doi/10.1139/...

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This new Review by Daphne Merkus and colleagues discusses evidence for overlap in patients with #coronary #microvascular disease and #heartfailure with preserved ejection fraction, shared #biomarkers and possibilities for #cardiometabolic interventions.
#Cardiovascular

doi.org/10.14814/phy...

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Microvascular Insights Into Hyaluronic Acid Filler Dispersal Within an Artificial Model of Arterial Embolism AbstractBackground. Hyaluronic acid (HA) filler-induced vascular occlusion is a serious complication in aesthetic medicine, yet the microvascular behavior

🧪 New co-author study in Aesthetic Surgery Journal!
HA fillers fragment into microparticles that occlude vessels ≤300 µm—supporting a microembolic model of ischemia.
Cannula size, gel rheology, & vessel anatomy matter.
Read: doi.org/10.1093/asj/...
#AestheticMedicine #FillerSafety #Microvascular

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New research on acute intermittent passive stretching (PS) or #ischemic #preconditioning shows each increase #microvascular responsiveness and #muscle oxidative capacity, suggesting PS as a possible intervention for individuals unable to take traditional #exercise.
doi.org/10.14814/phy...
#MyoBlue

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The Role of Capillary Health in Long COVID Recovery Long COVID affects many individuals, with symptoms linked to microclots that hinder oxygen delivery. However, new research indicates vascular injuries, such as capillary rarefaction and endothelial…

Everyone’s chasing clots, but the real damage might be hiding in plain sight inside your capillaries.

Impaired perfusion, endothelial stress, mitochondrial fallout… all in vessels you need a microscope to see.

More on longcovidjourney.com/2025/07/23/t...

#LongCovid #Microvascular #Endothelium

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🧠 “It’s anxiety.”
🩸 Meanwhile:
– Impaired flow
– Platelet chaos
– Endothelial distress

Long COVID isn’t in your head.
It’s in your vessels.

More on longcovidjourney.com

#LongCOVID #Microvascular #PASC #MedTwitter #microclot
#endothelium

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humorous cartoon shows a doctor holding a magnifying glass over a patient’s fingernail. Inside the magnified view, red blood cells are screaming as they ride through chaotic, twisted capillaries like a roller coaster. The patient looks surprised, and the caption reads: “When Long COVID takes your capillaries on a wild ride.”

humorous cartoon shows a doctor holding a magnifying glass over a patient’s fingernail. Inside the magnified view, red blood cells are screaming as they ride through chaotic, twisted capillaries like a roller coaster. The patient looks surprised, and the caption reads: “When Long COVID takes your capillaries on a wild ride.”

What can your fingernails reveal about Long COVID?
More than you think.

#Capillaroscopy shows tiny blood vessels and in Long COVID, they often look damaged, sluggish, or twisted.

Long COVID isn’t “just fatigue.” It’s in your blood flow.

Longcovidjourney.com

#LongCOVID #Microvascular #Chronic

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#Medsky🧪 #IDsky #immunosky #publichealth #Microangiopathy is a major complication of #Covid & contributes to the acute and chronic complications #Longcovid sequelae #Endotheliopathy & dysregulated 🩸 coagulation are prominent in COVID & are considered to be major causes of #microvascular obstruction

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1st BlueSky post =

Sharing fascinating images - #light & #microvascular assessment from my #research lab, #Coventry #University.

Exciting research: Raynaud's, SSc, diabetes, heart & vascular.

Centre for Intelligent Healthcare pureportal.coventry.ac.uk/en/persons/j...

Can you name the techniques?

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The role of cocoa flavanols in modulating peripheral and cerebral microvascular function in healthy individuals and populations at-risk of cardiovascular disease: a systematic review - Nutrition Journ... Background Cocoa flavanols (CFs) are polyphenolic molecules with proposed cardioprotective effects. Whilst extensive evidence supports their ability to ameliorate vasodilator responses within conduit ...

There is evidence to suggest that #cocoa flavanols may reduce resting #microvascular tone and improve #vasodilator responses across skeletal #muscle, skin and cerebral #circulation, particularly when administered acutely.

nutritionj.biomedcentral.com/articles/10....

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Impaired endothelial function contributes to cardiac dysfunction: role of mitochondrial dynamics | American Journal of Physiology-Heart and Circulatory Physiology The endothelial microvasculature is essential for the regulation of vasodilation and vasoconstriction, and improved functioning of the endothelium is linked to improved outcomes for individuals with coronary artery disease (CAD). People with endothelial dysfunction exhibit a loss of nitric oxide (NO)-mediated vasodilation, achieving vasodilation instead through mitochondria-derived H2O2. Mitochondrial dynamics is an important autoregulatory mechanism that contributes to mitochondrial and endothelial homeostasis and plays a role in the formation of reactive oxygen species (ROS), including H2O2. Dysregulation of mitochondrial dynamics leads to increased ROS production, decreased ATP production, impaired metabolism, activation of pathological signal transduction, impaired calcium sensing, and inflammation. We hypothesize that dysregulation of endothelial mitochondrial dynamics plays a crucial role in the endothelial microvascular dysfunction seen in individuals with CAD. Therefore, proper regulation of endothelial mitochondrial dynamics may be a suitable treatment for individuals with endothelial microvascular dysfunction, and we furthermore postulate that improving this microvascular dysfunction will directly improve outcomes for those with CAD.

Dysregulation of endothelial mitochondrial dynamics plays a crucial role in endothelial #microvascular dysfunction in individuals with #CoronaryArteryDisease. Read more about improving this microvascular dysfunction to improve outcomes for those with CAD ❤️🧪#AJPHeart&Circ ow.ly/G2Np50Uz390

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Prevalence, pattern, and potential predictors of #microvascular complications in aging Nigerians with type 2 diabetes | doi.org/10.4081/gc.2... | #openaccess #Nigeria #elderly #geriatrics

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Frontiers Publishing Partnerships | Shedding Light on Microvascular Inflammation: Understanding Outcomes, But What Sparks the Flame? In their recent article, Drs. Sablik and Sannier, along with more than 40 international collaborators, examined the impact of different microvascular inflamm...

Shedding Light on #Microvascular #Inflammation: Understanding Outcomes, But What Sparks the Flame? www.frontierspartnerships.org/journals/tra... #hvhebron #nefro [Text complet]

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#MedSky🧪#IDsky #NeuroCOVID #Vascularbiology Clear evidence of #microvascular damage, and breakdown of the BBB and BCSFB in vivo, demonstrating that the #CNS barrier dysfunction is an important aspect of #COVID19.
www.biorxiv.org/content/10.1...

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MedSky🧪#IDSky #pedSky @JAMAPediatrics #LongCovidkid This study found significant, long term persistent #microvascular damage with redistribution of the vessel architecture (ie, loss of capillaries with relative increase in larger vessels) in patients with MIS-C

jamanetwork.com/journals/jam...

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