Using #SingleMolecule imaging we find that TFs:

-boost co-transcriptional #ribosomal #RNA processing!

-their binding #dynamics fundamentally differ for mRNA (transient) versus rRNA #transcription (stable)!

@biorxivpreprint.bsky.social Anastasiia Chaban @embl.org

www.biorxiv.org/content/10.6...

How do you study a gene that the plant can't live without?
The answer lies in the 5′UTR. A new paper in Plant Physiology demonstrates how #CRISPR-mediated 5′UTR editing can "dial down" the expression of the essential #ribosomal #protein UL3Z.
doi.org/10.1093/plph...

#Pseudogenes aren’t always silent 🧬 RPS27AP5, once considered non-functional, produces a #ubiquitin variant (UbP5) and #ribosomal #protein variant (S27aP5) that alters #mRNA association, adding evidence for ribosome diversity 👏
https://ow.ly/hsNn50Yh11e

#JJC2026 @vincent-moulin.bsky.social (Institute of Forest Ecology, Slovak Academy of Science) on sequencing of total #ribosomal #DNA from #endophytes in #spruce bark using Oxford Nanopore technology

Ribosomal engineering creates 'super-probiotic' bacteria with enhanced immune activation Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG). These mutant…

#Ribosomal engineering creates 'super-probiotic' #bacteria with enhanced immune activation ...

| #Lacticaseibacillus | #probiotics | #lacticacid | #microbiota | Via @sciencex.bsky.social

Stop #mycoplasma contamination before it spreads!

flip from FuseDx is a new #molecular detection device that reveals mycoplasma 16S #ribosomal #RNA in #cellculture in just 12 minutes from sample to results
Ask us for a demo

🔗 www.stratech.co.uk/our-partners/fuse_diagno...

#bioscience

Rpl12 is a conserved ribophagy receptor - Nature Cell Biology Chen, Hu, Zhao, Fang and colleagues show that the ribosomal large subunit protein Rpl12 functions as a conserved ribophagy receptor in multiple organisms.

☕Chen, Hu, Zhao, Fang & co show that the #ribosomal large subunit protein Rpl12 functions as a conserved #ribophagy receptor in multiple organisms.
rdcu.be/eevML
bit.ly/4hveoet

An avoidance segment resolves a lethal nuclear–mitochondrial targeting conflict during ribosome assembly - Nature Cell Biology Oborská-Oplová et al. report a conserved mitochondrial avoidance segment in the cytosolic ribosomal protein uS5 that prevents mistargeting of uS5 to the mitochondrial matrix and ensures cytosolic ribosomal assembly.

☕️Oborská-Oplová et al. report a conserved #mitochondria avoidance segment in the cytosolic ribosomal protein uS5 that prevents mistargeting of uS5 to the mitochondrial matrix and ensures cytosolic #ribosomal assembly.
👉https://rdcu.be/ecb32
bit.ly/4bz49Ev

Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells Interplay between signaling pathways and ribosomal biogenesis supports the proliferation of activated T cells.

Reciprocal regulation of #mTORC1 signaling and #ribosomal biosynthesis determines #cellcycle #progression in activated #T_cells: www.science.org/doi/10.1126/...

Anyone has a good couple of #primers recognising human #ribosomal #RNA?