Dr. David Tobin's team at @dukemedschool.bsky.social used a zebrafish infection model and a #granuloma explant model to study neutrophil dynamics and functions during a critical phase of infection. #Tuberculosis

🔓 Get the full story here: bit.ly/3ZBWSOW

In a new @jem.org study from Mbano, Liu, Leslie et al., single-cell and spatial transcriptomics of human #TB lung tissues from individuals in South Africa revealed that MMP1⁺CXCL5⁺ #fibroblasts & SPP1⁺ #macrophages are linked to TB disease & TB lung #granuloma rupress.org/jem/article/...

In a new study from Mbano, Liu, Leslie et al., single-cell and spatial transcriptomics of human #TB lung tissues from individuals in South Africa revealed that MMP1⁺CXCL5⁺ #fibroblasts & SPP1⁺ #macrophages are linked to TB disease & TB lung #granuloma rupress.org/jem/article/...

#InfectiousDisease

Treatment of benign inguinal lymphogranulomatosis #infection #lymphoma #granuloma #epsteinbarrvirus
... Continue to: youtube.com/shorts/XHkCQ...

Caroline Beltran & co describe a novel and unbiased 3D imaging approach that visualises how the lung granulomas that are characteristic of TB infection form, evolve & spatially organise. 🐭 🫁 doi.org/10.1242/dmm....

#Tuberculosis #Granuloma

AMP just published!
”Palisaded Neutrophilic Granulomatous Dermatitis as the Initial Manifestation of Rheumatoid Arthritis”

Full paper here:
www.actamedicaportuguesa.com/revista/inde...

#autoimmunediseases #dermatitis #granuloma #neutrophils #rheumatoidarthritis #actamedicaportuguesa

#granuloma #inguinale ddx Disseminated histoplasmosis may present as genital ulcer but fever, weight loss, anorexia are prominent.

DDx #granuloma #inguinale is painless like like syphilitic ulcers & LGV
-Chancroid (H. ducreyi) painful ulcerations (like HSV) that heal spontaneously & often w/suppurative inguinal lymphadenitis.
HSV painful lesions but unlike chancroid: no suppurative adenitis.

Clinically, #granuloma #inguinale is painless, slowly progressive ulcerative lesions on genitals or perineum without regional lymphadenopathy; subcutaneous granulomas (pseudobuboes) also might occur. The lesions are highly vascular (i.e., beefy red appearance) & bleed #donovanosis

🔥 What Really Happens When a Tiny Pebble Gets Trapped Inside a Wound?

Check it out:
👉 patreon.com/go4know

#knowledge #curiosity #education #ai #aiart #art #biology #wounds #healing #immunology #science #infection #skin #injury #medicine #microbiology #granuloma #health #anatomy #human #body

SOX9 plays an essential role in myofibroblast driven hepatic granuloma integrity and parenchymal repair during schistosomiasis-induced liver damage Author summary Mammalian infection with schistosome worms results in the deposition of parasite eggs in the liver, where they secrete organ damaging toxins. In response, the liver generates a cellular...

Delighted to share our paper on the role of SOX9 in liver #fibrosis and #granuloma formation during #schistosome infection - a really great collaboration over the past few years with the Piper Hanley lab! #ImmunSky 🪱🧪

dx.plos.org/10.1371/jour...

Pulmonary Hyalinizing #Granuloma With Favourable and Longitudinal Treatment Response
onlinelibrary.wiley.com/doi/10.1002/...

Topical Timolol in the Treatment of #Hemodialysis Tunneled Catheter Exit-Site Pyogenic #Granuloma

#KIRNephrologyRounds

🙌🏼🙌🏼🙌🏼🙌🏼 Check out this tour-de-force work on #granuloma organization!!
@erin-mccaffrey.bsky.social
We are lucky to have you at the IRP at NIH!