Acupuncture Treats Sepsis through Immune Modulation and Organ Protection

This study reviews how #Acupuncture & #Synergistic drug–acupuncture regulate #Immune function & protect target organs in #Sepsis, underscoring the #therapeutic potential of acupuncture in both #Immunomodulation & #OrganProtection. #medsky
Read: doi.org/10.1007/s115...

A new issue of #ACS Applied Materials & Interfaces (@ACS_AMI) is live! On the #cover an #article about #HDL-Functionalized #Biomaterial #Coatings Provide Favorable #Immunomodulation and Enhance #Osteogenesis

📢New call for submissions 📢

📢 Innovations in Therapeutic Interventions: Advancing Clinical and Experimental Medicine 📢

MORE INFORMATION
advances.umw.edu.pl/en/innovations

#PrecisionMedicine #PersonalizedTherapy #Immunotherapy #Immunomodulation #GeneTherapy #CellTherapy #RegenerativeMedicine

Mesenchymal stem cell–mediated renal remodeling in lupus nephritis
MSCs reshape renal inflammation via CXCL10-CXCR3 recruitment and IL4I1 signaling in lupus nephritis.
www.nature.com/articles/s41...
#MesenchymalStemCells #LupusNephritis #RenalDisease #Immunomodulation

🚨 ULTRASOUND IS NO LONGER JUST IMAGING. IT’S THERAPY.
💥 One pulse. One organ. System-wide immune modulation.

#Ultrasound #POCUS #NeuroImmunology #VagusNerve
#CriticalCare #Sepsis #AKI #Immunomodulation
#MedicalInnovation #FOAMed #MedInstagram
#EvidenceBasedMedicine #FutureOfMedicine

This study presents BCCe6, a multifunctional colloidal self-assembled crystal that integrates photodynamic and immunomodulatory functions as a novel platform for antibacterial therapy and tissue repair.
doi.org/10.59717/j.x...
#LifeSciences #photoresponsive #immunomodulation

Calling all researchers 📣 Get support for your research on #ECP #immunomodulation by applying to this grant, supported by Therakos LLC.

Improve patient survival, health-related quality of life, & stabilize organ function in #thoracictransplant patients. 🫀

✍️Get more information at 🔗 bit.ly/3PyoxLE

Skin Repairing Procedure Inspired Polypyrrole/Bacterial Cellulose/Platelet Rich Plasma Composite Hydrogel as Diabetes Wound Dressing Diabetic ulcers represent a kind of severe chronic wound that presents significant challenges to global healthcare systems. The impaired healing proce…

Yang et al. designed a #polypyrrole/#bacterial cellulose/#platelet-rich plasma #hydrogel #dressing to achieve synergistic #antibacterial efficacy, #immunomodulation of the #wound microenvironment,
DOI: 10.1016/j.jobab.2025.10.004
www.sciencedirect.com/science/arti...

[ALA Client News] Exeliom Biosciences secures €2.85M extension to Series A funding, bringing total round to nearly €12M

ala.associates/funding/exel...

#fundraising #immunomodulation #inflammatorydisease #oncology

Ultrasound activated herbal bio-heterojunctions for self-catalytic regulation and bacterial cuproptosis-like death in the treatment of implant infection - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Ultrasound activated herbal bio-heterojunctions for self-catalytic regulation and bacterial cuproptosis-like death in the treatment of implant infection

A novel ultrasound-responsive herbal bioheterojunction (HB-bioHJ)—Cu2O-Sr/Cur—demonstrates #Cuproptosis-like antibacterial activity, #Immunomodulation, and #osteogenesis for treating #ImplantAssociatedInfections (IAIs). #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

New Spotlight alert! The bite that binds: #mosquito #saliva mediates #TLR2-driven #flavivirus infection, authored by Laura Willen & Fabiano Oliveira, highlighting Y. Matsuura, T. Okamoto & colleagues’ @cp-cellreports.bsky.social article. #immunomodulation

authors.elsevier.com/a/1llns5Eb1x...

Electromodulation of human monocyte-derived macrophages drives a regenerative phenotype and impedes inflammation O’Rourke et al. demonstrate that external delivery of electrical stimulation regulates the function of innate immune cells, macrophages, to favor tissue repair and regeneration. These findings are rel...

Electromodulation of human monocyte-derived macrophages drives a regenerative phenotype and impedes inflammation #aging #regeneration #electromodulation #immunomodulation #inflammation

www.cell.com/cell-reports...

New Review alert! #Mansonella #perstans – the forgotten #filaria, authored by Manuel Ritter, Hsun Hsu, Benjamin Lenz, Chi Kien, Narcisse Gandjui, Marc Hübner, Achim Hoerauf & Samuel Wanji #mansonellosis #immunomodulation #Culicoides #midges #oxfendazole @dzif.bsky.social
www.cell.com/trends/paras...

Dr Nathalie Boulanger reviews #tick & host #microbiotas: #immunomodulators in #tickborne diseases. #Microbiota #Metagenomics #Skin #Immunity #Immunomodulation @chrustrasbourg.bsky.social‬

authors.elsevier.com/a/1lZFX5Eb1x...

PhD Position: Interactive biomaterials for immune modulation in regenerative medicine PhD Position: Interactive biomaterials for immune modulation in regenerative medicine

PhD vacancy:
I'm excited to share a PhD position available in my group on the topic: "Interactive biomaterials for immune modulation in regenerative medicine."
See more: merlninstitute.com/careers/vaca...
#PhDposition #Vacancy #Biomaterials #Immunomodulation #RegenerativeMedicine #ChemistryJobs

Mohammed Elmallah (Inserm UMR1327, Tours)
"Immunomodulatory effects of breast cancer MDA-MB-231- cell-derived extracellular vesicles on monocyte-derived dendritic cells: Implication of P2X4 purinergoc receptor"
#FPC2025 #PurinergicSignaling | #BreastCancer #Immunomodulation

A systematic review on leptin’s role in defining cancer: special emphasis on immunomodulation, inflammation, and therapeutic interventions - Genes & Immunity Genes & Immunity - A systematic review on leptin’s role in defining cancer: special emphasis on immunomodulation, inflammation, and therapeutic interventions

A #systematic #review on #leptin’s role in defining #cancer: special emphasis on #immunomodulation, #inflammation, and #therapeutic #interventions

#Genes & #Immunity @springernature.com
www.nature.com/articles/s41...

Light-Powered Phagobots: Dual-Mode Optical Control of Living Immune Microrobots | Newswise Immunomodulation based on macrophages shows great potential in tackling major diseases such as infections and cancers. However, precision control of these cells in vivo has proven challenging. To solv...

Light-Powered Phagobots: Dual-Mode Optical Control of Living Immune Microrobots
www.newswise.com/articles/lig...
#Immunomodulation #immunecells #Macrophages

LL-37 and citrullinated-LL-37 modulate IL-17A/F-mediated responses and selectively suppress Lipocalin-2 in bronchial epithelial cells - PubMed Overall, our findings showed that LL-37 and citLL-37 can selectively suppress the abundance of IL-17A/F-mediated LCN-2, a protein that is critical for neutrophil migration in HBEC. These results sugge...

Sharing our latest publication on modulation of IL-17 mediated inflammation by #HostDefencePeptide LL-37 and citrullinated-LL-37 in the context of lung inflammation #Asthma #Immunosky #Immunomodulation #AntimicrobialPeptides pubmed.ncbi.nlm.nih.gov/40410820/

Eleva publishes evidence in preclinical dry AMD study – Eleva Biologics

Happy to see that eleva, the company I founded 26 years ago, is progressing so well with #moss-made human factor H.
Eleva publishes evidence of #immunomodulation and #neuroprotection using its Factor H biological therapy in preclinical dry #AMD study
elevabiologics.com/eleva-publis...

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

👉 buff.ly/hXoywDz

#Immunosuppression #CancerMetastasis #Immunomodulation

Dr Bart Everts highlights Julia Esser-von Bieren & colleagues’ Science Immunology article on #helminths targeting #macrophage #epigenetics & #metabolism to evade #immunity. #Immunomodulation #ProstaglandinE2 @tum.de @www.helmholtz-munich.de

authors.elsevier.com/a/1kbrX5Eb1x...

First evidence of #immunomodulation of the renin-angiotensin system through substance P/neurokinin 1 #receptor: a case and control study in #hypertension and cardiac patients | doi.org/10.4081/itjm... | #MedSky #AcademicSky #cardiology

Molecular and biological characterization of transforming growth factor-β homolog derived from Trichinella spiralis - Scientific Reports Scientific Reports - Molecular and biological characterization of transforming growth factor-β homolog derived from Trichinella spiralis

Characterization of the basic properties and functions of #TGF-β homologs in #Trichinella & their interaction with the human TGF-β receptor. A factor involved in the #immunomodulation induced by the parasite?
www.nature.com/articles/s41...

PhD Application 2025 The Graduate Research Training Group 2873 “Tools and Drugs of the Future – Innovative Methods and New Modalities in Medicinal Chemistry”, funded by the German Research Foundation (DFG) offers 12 PhD P...

🎓 PhD Opening 🎓

We are looking for top candidates for a PhD on #immunomodulation of ‘cryptic’ host defense #peptides. Join #GRK2873 @unibonn.bsky.social @UKBonn 🧪 #PhD #Pharmacology #InnateImmunity #DFG

Project starts Oct 2025. Let's connect!

👇

www.grk2873.uni-bonn.de/en/training-...

What to expect if you follow me?
I post a few times a week and repost relevant stuff from others on the following themes:
#SystemsBiology
#HumanMicrobiome
#ImmuneHealth
#SpaceHealth
#HumanImmunology
#Autoimmunity
#Immunomodulation
#SystemsImmunology

#Mentorship
#InclusiveMentorship
#scienceCulture

Implants made of magnesium (Mg) are increasingly employed in patients to achieve osteosynthesis while degrading in situ. Since Mg implants and Mg2+ have been suggested to possess anti-inflammatory properties, the clinically observed soft tissue inflammation around Mg implants is enigmatic. Here, using a rat soft tissue model and a 1–28 d observation period, we determined the temporo-spatial cell distribution and behavior in relation to sequential changes of pure Mg implant surface properties and Mg2+ release. Compared to nondegradable titanium (Ti) implants, Mg degradation exacerbated initial inflammation. Release of Mg degradation products at the tissue-implant interface, culminating at 3 d, actively initiated chemotaxis and upregulated mRNA and protein immunomodulatory markers, particularly inducible nitric oxide synthase and toll-like receptor-4 up to 6 d, yet without a cytotoxic effect.

🔬🦴🧪 Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues" 🔎

doi.org/10.1016/j.bi...

#biomaterials #tissueengineering #regenerativemedicine #biology #implants #inflammation #immunomodulation #fibrosis