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If you are interest on how Drosophila melanogaster integrates internal signals and environmental cues to regulate reproduction take a look at this book chapter!
#fruitfly #drosophila #oogenesis

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Developmentally regulated #actin-#microtubule crosstalk in #Drosophila #oogenesis. New study from Wei-Chien Chou, Brooke M. McCartney and colleagues @cmu.edu: rupress.org/jcb/article/...

#Cytoskeleton #Development

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New study from Chou, McCartney et al. @cmu.edu demonstrates coregulation of #actin filament assembly/bundling and #microtubule nucleation/organization during #Drosophila #oogenesis, highlighting the coordinated regulation of the #cytoskeleton required during #development. rupress.org/jcb/article/...

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In @jcb.org, Chou, McCartney et al. @cmu.edu demonstrate coregulation of #actin filament assembly/bundling and #microtubule nucleation/organization during #Drosophila #oogenesis, highlighting the coordinated regulation of the #cytoskeleton required during #development. rupress.org/jcb/article/...

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Rodrigo Dutra Nunes, a postdoctoral researcher at the Johns Hopkins Bloomberg School of Public Health, uses the #Drosophila model system to study the effects of high sugar diet on #oogenesis and #fertility.

7/19🧵

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Modules propose a new morphogenetic framework for #oogenesis in vertebrates, with important implications to stem cell biology and reproduction.

Ex Ovo Omnia!
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Super proud of Neta Hart for being awarded the travel grant by The Science Bank and for delivering an excellent talk at the Notch Signaling Meeting about her pioneering work on newly identified mode of early #oogenesis in #zebrafish and human, regulated by Notch (more to come!).

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Eugenia Maria del Pino Veintimilla, PhD - STEMMCHEQ Dr. Eugeneia Maria del Pino was born on April 19, 1945 in Quito, Ecuador. She received a Licentiate Degree (1967) from the Pontifical Catholic University of Ecuador (PUCE), a MSc (1969) from Vassar Co...

Dr. Eugenia Maria del Pino Veintimilla is an Eduadorian #DevelopmentalBiologist that made significant contributions in understanding egg development in #frogs, primarily trained undergrads, and big champion of #mentorship.
#oogenesis #HispanicHeritageMonth

www.scheq.org/eugenia-mari...

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Eugenia Maria del Pino Veintimilla, PhD - STEMMCHEQ Dr. Eugeneia Maria del Pino was born on April 19, 1945 in Quito, Ecuador. She received a Licentiate Degree (1967) from the Pontifical Catholic University of Ecuador (PUCE), a MSc (1969) from Vassar Co...

Dr. Eugenia Maria del Pino Veintimilla is an Eduadorian #DevelopmentalBiologist that made significant contributions in understanding egg development in #frogs, primarily trained undergrads, and big champion of #mentorship.
#oogenesis #HispanicHeritageMonth

www.scheq.org/eugenia-mari...

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Diagram captioned "Rules of regeneration". Centre, a polar coordinate system; bottom left, a Drosophila wing imaginal disc; bottom right, a tetrapod limb; upper right, an insect limb.

Diagram captioned "Rules of regeneration". Centre, a polar coordinate system; bottom left, a Drosophila wing imaginal disc; bottom right, a tetrapod limb; upper right, an insect limb.

#DBFeature 🌐

Origins, findings, challenges, and influence of the Polar Coordinate Model, which revolutionized understanding of limb regeneration by framing pattern formation as positional information encoded in coordinate ‘maps’ across tissues.

#SpecialIssue on #Oogenesis in animals and plants

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D reconstruction of the Sunburst Nuclear Envelope Vesicles. (A) Type III cells. Green sheet = nuclear envelope. Dots = nuclear pore complexes. Purple and red buds = Sunburst Nuclear Envelope Vesicles. (B) Type IV cells. Cyan sheet = nuclear envelope. Dots = nuclear pore complexes. Green, Red, Blue, Purple coral shapes = Sunburst Nuclear Envelope Vesicles. (C) Type V cells. Green sheet = nuclear envelope. Dots = nuclear pore complexes. The rest = Sunburst Nuclear Envelope Vesicles. (D–E) The same Sunburst Nuclear Envelope Vesicle sectioned at different positions. N = nucleoplasm. C = cytoplasm. Ribosomes on nuclear envelope (green sheet) were present but not illustrated. (F–G) The same Sunburst Nuclear Envelope Vesicle viewed from different angles. N = nucleoplasm. C = cytoplasm. Dumbbell shapes in F. (H–I) The same Sunburst Nuclear Envelope Vesicle sectioned at different positions. N = nucleoplasm. C = cytoplasm. Dumbbell shapes in H. Double rings in I.

D reconstruction of the Sunburst Nuclear Envelope Vesicles. (A) Type III cells. Green sheet = nuclear envelope. Dots = nuclear pore complexes. Purple and red buds = Sunburst Nuclear Envelope Vesicles. (B) Type IV cells. Cyan sheet = nuclear envelope. Dots = nuclear pore complexes. Green, Red, Blue, Purple coral shapes = Sunburst Nuclear Envelope Vesicles. (C) Type V cells. Green sheet = nuclear envelope. Dots = nuclear pore complexes. The rest = Sunburst Nuclear Envelope Vesicles. (D–E) The same Sunburst Nuclear Envelope Vesicle sectioned at different positions. N = nucleoplasm. C = cytoplasm. Ribosomes on nuclear envelope (green sheet) were present but not illustrated. (F–G) The same Sunburst Nuclear Envelope Vesicle viewed from different angles. N = nucleoplasm. C = cytoplasm. Dumbbell shapes in F. (H–I) The same Sunburst Nuclear Envelope Vesicle sectioned at different positions. N = nucleoplasm. C = cytoplasm. Dumbbell shapes in H. Double rings in I.

#DBFeature 🪱

During oogenesis in planarian S. mediterranea, the nuclear envelope transforms into Sunburst Nuclear Envelope Vescicles that contain nuclear proteins but lack DNA and nuclear pores

By Longhua Guo et al.

tinyurl.com/4n5wwps8

#SpecialIssue on #Oogenesis in animals and plants

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Driven to cannibalism: a hormonal trigger for #phagocytosis. Amanda Powell and Elizabeth Ables @eastcarolinauniv.bsky.social discuss new work from Ghosh et al. (rupress.org/jcb/article/...), in Spotlight: rupress.org/jcb/article/...

#Drosophila #Oogenesis #Development

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Scientists recreate mouse egg cell development without ovarian support cells Researchers from Japan and France have successfully reconstituted the development of mouse egg cells, known as oocytes, from embryonic stem cells entirely in vitro, without the need for ovarian support cells. This new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for future applications in human reproductive biology. The findings are published in the journal Developmental Cell.

✨Scientists grew egg cells 🌱 entirely in a lab!🤯 No ovary needed! Unlocking secrets of life & paving the way for future reproductive breakthroughs!🔬 #oogenesis

Source: phys.org/news/2025-07-scientists-...

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Spotlight in @jcb.org: Powell and Ables @eastcarolinauniv.bsky.social discuss work from Ghosh et al. (rupress.org/jcb/article/...), which reveals that ecdysone signaling reprograms epithelial follicle cells toward a phagocytic fate during #Drosophila late #oogenesis. rupress.org/jcb/article/...

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Powell and Ables @eastcarolinauniv.bsky.social discuss work from Ghosh et al. (rupress.org/jcb/article/...), which reveals that ecdysone signaling reprograms epithelial follicle cells toward a phagocytic fate during #Drosophila late #oogenesis. rupress.org/jcb/article/...

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Ecdysone regulates phagocytic cell fate of epithelial cells in developing #Drosophila eggs. New study from Gaurab Ghosh, Mohit Prasad and colleagues (Indian Institute of Science Education and Research Kolkata): rupress.org/jcb/article/...

#Development #CellDeath #Oogenesis

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Ghosh, Prasad et al. elucidate the role of ecdysone signaling in orchestrating the removal of nurse cells by transforming the epithelial follicle cells to a phagocytic fate during late #Drosophila #oogenesis. rupress.org/jcb/article/...

#Development #CellDeath

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In @jcb.org, Ghosh, Prasad et al. elucidate the role of ecdysone signaling in orchestrating the removal of nurse cells by transforming the epithelial follicle cells to a phagocytic fate during late #Drosophila #oogenesis. rupress.org/jcb/article/...

#Development #CellDeath

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Graphical abstract of: Depletion of Gtsf1L impairs development of eupyrene sperm and ovary in Bombyx mori

Graphical abstract of: Depletion of Gtsf1L impairs development of eupyrene sperm and ovary in Bombyx mori

New research published in #RESInsectMolecBio shows depletion of Gtsf1L impairs development of eupyrene sperm and ovary in #BombyMori🧬

Read the article now🔽
doi.org/10.1111/imb.12988

@sassanasgari.bsky.social @gulianusslab.bsky.social @wiley.com
#oogenesis #SexDetermination #spermatogenesis

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Defining the roles of the Integrator, NEXT, and nuclear exosome complexes in Drosophila oogenesis Nuclear RNA homeostasis depends on the balance of transcription, RNA processing, degradation, and transport between the nucleus and cytoplasm. RNA degradation directed by the Integrator, nuclear exoso...

Interesting! #RNADecay #RNAExosome #RNA #ncRNA

Defining the roles of the #Integrator, #NEXT, and #nuclear #exosome complexes in #Drosophila #oogenesis
Yongjin Lee, Adriano Biasini, Cindy Tipping, Seong Hyeon Hong, Phillip Zamore

www.biorxiv.org/content/10.1...

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Here, we identify three novel regulators of #oogenesis in #zebrafish - mTOR, Stat3, and Stathmin, with unpredicted roles in controlling oocyte polarity and formation of the Balbiani body, a conserved oocyte #condensate.
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Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu

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Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu

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Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Top: Scheme of an ovariole, oriented from the anterior (A) to the posterior (P) end, as in all the subsequent images. The ovariole starts with the germarium from which young follicles bud before undergoing massive growth until the formation of an egg at the posterior end. In each follicle, somatic follicle cells (in purple) surround a germline cyst with the nurse cells (pink) and the oocyte (in blue). Bottom left: Somatic Inx2A mutant clones, marked by the absence of RFP expression, induce a germline growth defect when they cover the whole epithelium (arrow) compared with the wild-type younger follicle (n − 1) (arrowhead). Bottom right: Maximum intensity projection of immunostaining for Inx2 (green) and Inx4 (magenta) in follicles containing Inx4 RNAi-expressing germline clones visualized by Inx4 absence. Note the absence of Inx2 plaques at germline contacts at higher magnification and the growth defect of Inx4 RNAi follicles (arrow) compared with the wild-type younger follicle (arrowhead).

Gap junctions allow transfer of small molecules between cells. @mirouse-lab.bsky.social &co show that #GapJunctions allow the exchange of metabolites between germ cells & somatic cells to promote germline growth during #Drosophila #oogenesis 🧪 @plosbiology.org plos.io/3CYrZwu

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During egg cell development (oogenesis), a germ cell divides into multiple daughter cells. As part of a process that's still something of a mystery, one cell becomes the egg cell, or oocyte, shown here in light micrograph.

During egg cell development (oogenesis), a germ cell divides into multiple daughter cells. As part of a process that's still something of a mystery, one cell becomes the egg cell, or oocyte, shown here in light micrograph.

Dynamic imaging reveals how egg cells emerge. In PNAS Journal Cub: www.pnas.org/post/journal...

#oocyte #oogenesis #DevelopmentalBiology #3DImaging

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Super-talented PhD student, Swastik Kar, will present his work: The Balbiani body is generated by microtubule controlled molecular #condensation in early #oogenesis
Presentation: P1792
Poster Session: Liquid Phase Separation 1
Monday, 11:15 AM - 12:45PM
Board: B97
Exhibit Halls D-G

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The team @LenartLab use them to study the division and maturation processes in living #oocytes. They want to understand the basic processes of #oogenesis and they investigate how the cell division machinery has adapted to produce the fertilizable egg in the process of #meiosis.⬇

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Our research group @LenartLab is #hiring! Are you looking for a #PhD position in the field of imaging #oogenesis live by light sheet #microscopy? Check out the #job ad: 👇
https://www.mpinat.mpg.de/75-22?c=641415
Please RT!

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🔠 #MPINAT_ABC#J like Jellyfish @lenartlab works with our jellyfish 💧 to study #oogenesis and to understand how the cell division machinery, in particular the cytoskeleton, has adapted to the process of #meiosis. https://www.mpinat.mpg.de/lenart

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