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Exposing tumors: Why some cancers are especially hard to treat Some tumors go into

New on the LJI Blog —

Some tumors go into "stealth mode." Here's how scientists are fighting back: bit.ly/4v7lC0d

#Cancer #CancerImmunotherapy #Virology #Health #Medicine

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It was a great pleasure to speak two weeks ago at the Annual Meeting of the Portuguese Society of Immunology in Coimbra!

#SPI #Immunology #CancerImmunotherapy

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Zelig Eshhar: The Pioneer Who Re-Engineered the T-Cells and Brought CAR-T into the World

dl.begellhouse.com/journals/439...

#CARTCellTherapy #CancerImmunotherapy #TcellEngineering #CRO

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Engineered Extracellular Vesicles for Cancer Immunotherapy | MedChemExpress Engineered extracellular vesicles (EVs) surpass their natural counterparts by offering enhanced targeting capabilities and the ability to deliver specific therapeutic agents with high precision.…

🔬Gain new insights into the development and therapeutic potential of engineered EVs. Stay informed with science updates curated for your research interests. ow.ly/T2eb50YxVMl

#CancerImmunotherapy #CancerResearch #Immunotherapy #DrugDelivery #ExtracellularVesicles #BiomedicalResearch

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Scientists “turbocharge” immune cells to attack prostate cancer – BioNews Central A new class of engineered, supercharged T cells is stronger, longer-lasting, and more precise at killing prostate cancer cells by fine-tuning how they physically interact with tumor cells. ...

A new class of engineered, supercharged #TCells is stronger, longer-lasting, and more precise at killing #ProstateCancer cells by fine-tuning how they physically interact with #TumorCells.
#ProstateCancerTreatment #CancerImmunotherapy #EngineeredTCells

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Harnessing Radiation Effects on the Immune System: Balancing Acts

www.dl.begellhouse.com/journals/2c6...

#RadiationOncology #CancerImmunotherapy #SpatiallyFractionatedRadiation #OT

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Watch our on-demand webinar and learn how researchers identified unique #TCR repertoire changes in the peripheral blood of a highly responsive patient following TIL therapy for colorectal cancer.

irepertoire.com/webinars-vid...

#CancerImmunotherapy #CellTherapy

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Register now for On Demand Access to @KeystoneSymposia.bsky.social #CancerImmunotherapy : Mechanisms, Clinical Advances and Combinations to explore emerging research! hubs.la/Q0445qFR0 #KSCancerImmune26

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Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations | Keystone Symposia Join us at the Keystone Symposia on Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations, March 2026, in Québec, with field leaders!

Our editor Lise Roth will be attending #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec with @keystoneSymposia.bsky.social

Reach out to talk about your research!

keysym.us/KSCancerImmune26 #KSCancerImmune26

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Researchers from the Fourth Military Medical University reported in Cancer Biology & Medicine a comprehensive review examining how gut microbial ecosystems regulate responses to PD-1/PD-L1 immunotherapy.
#Gutmicrobiota #cancerimmunotherapy
Details: doi.org/10.20892/j.issn.2095-3941.2025.0347

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We are looking forward to covering this new exciting #CancerImmunotherapy : Mechanisms, Clinical Advances and Combinations meeting, March 15-18 in Québec with @KeystoneSymposia.bsky.social
Take a look at their impressive line-up and register for On Demand: hubs.la/Q0445qFR0
#KSCancerImmune26

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#KSMYELOID26 #Immunology #CellReprogramming #CancerImmunotherapy

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MDM2 inhibitors in cancer immunotherapy: Current status and perspective

MDM2 inhibitors in cancer immunotherapy: Current status and perspective

An overview of MDM2’s role in regulating #CancerImmunotherapy, summarizing preclinical & clinical findings on #MDM2 inhibitors in combination with #Immunotherapy, and highlighting MDM2 inhibition as a therapeutic strategy.

#OpenAccess: doi.org/10.1016/j.ge...

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WTF Wire

WTF Wire

Cancer immunotherapy time of day may affect survival, with morning treatment linked to better outcomes.

#WTFWire, #CancerImmunotherapy, #CancerResearch, #CancerTreatment, #Immunotherapy, #Oncology, #CancerCare, #MedicalResearch, #HealthNews, #CancerAwareness

www.wtfwire.com/health/cance...

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DOR Inhibition & the Tumor Microenvironment
DOR Inhibition & the Tumor Microenvironment YouTube video by Unboxing Biotech

TuHURA Biosciences CEO Dr. James Bianco explains the mechanism of action for the Delta Opioid Receptor which modifies the tumor microenvironment rather than targeting the tumor itself.
$HURA
#ImmunoOncology #CancerResearch #CancerImmunotherapy #ImmuneSuppression #MDSCs
youtu.be/8xSUa9LjsNk

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🩸 More insights on bispecific antibody mechanisms and clinical development in Multiple Myeloma

#MultipleMyeloma #BispecificAntibodies #Immunotherapy #CancerImmunotherapy #GPRC5D #FcRH5 #TrispecificAntibodies #AntigenEscape #HemeOnc #HEMEHUB

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Abstract deadlines are coming up for the @‌keystoneSymposia.bsky.social #CancerImmunotherapy meeting this March in Québec.

Learn more about key dates and submission details:
hubs.la/Q03Xlgbv0

#KSCancerImmune26

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Honoring Dr. Jewett: Processed osteoclasts effectively "supercharge" NK cells for cancer therapy with faster prep and lower costs.

Free until Feb 15: www.dl.begellhouse.com/journals/2ff...

#NKCellTherapy #CancerImmunotherapy

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Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations | Keystone Symposia Join us at the Keystone Symposia on Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations, March 2026, in Québec, with field leaders!

Explore emerging research with field leaders @keystonesymposia.bsky.social #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03TCrxR0

#KSCancerImmune26

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Introducing an albumin-based “Catch-and-Play” platform for rapid assembly of interchangeable T-cell engagers with enhanced in vivo half-life, enabling customizable #TumorTargeting for personalized #CancerImmunotherapy.

#STTT #OpenAccess: doi.org/10.1038/s413...

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Promotional image for a Keystone Symposia event titled "Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations," scheduled for March 15-18, 2026, at Fairmont Le Château Frontenac, Quebec, QC, Canada. The background features a winter view of a cityscape with the Château Frontenac visible.

Promotional image for a Keystone Symposia event titled "Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations," scheduled for March 15-18, 2026, at Fairmont Le Château Frontenac, Quebec, QC, Canada. The background features a winter view of a cityscape with the Château Frontenac visible.

Explore emerging research with field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03Xlgbv0 #KSCancerImmune26

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Two obstacles in #CancerImmunotherapy are tumor-infiltrating T cell exhaustion & mitochondrial dysfunction.

Drs. @yapeng-su.bsky.social & Philip Greenberg at @fredhutch.org & @uwdeptmedicine.bsky.social identified KLHL6 as a dual-negative regulator of both.

Abstract: https://go.nature.com/4qqLAsK

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#Immunology #CancerImmunotherapy #Tcells #CheckpointInhibitors

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This comprehensive review by Dr. Anahid Jewett and UCLA researchers demonstrates how NK cells select and differentiate cancer stem cells, leading to growth inhibition and reduced metastasis.

Free to read until Feb 15th:
dl.begellhouse.com/journals/2ff...

#NKCells #CancerImmunotherapy

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Transforming Cancer Therapeutics: From Molecular Pathways to Patients in the Keystone Symposia 2026 Cancer Series Join Keystone Symposia’s 2026 Cancer Series—4 meetings advancing cancer therapy from molecular pathways to patient-centered care through discovery and innovation.

🚀 Join 4 connected Keystone Symposia on #CancerResearch: #Oncogenesis, #TumorMetabolism, #TumorMicroenvironment & #CancerImmunotherapy. Explore breakthroughs from molecular pathways to patients in prevention, detection, treatment & remission. 🔗 keypoint.keystonesymposia.org/home/transfo...

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🌐 Explore emerging research w/ field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, March 15-18 in Québec 🏰 JEM's Senior Editor @montse-jexpmed.bsky.social is attending!
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26

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🔗 Read more: bit.ly/ONCOnews14J-04

#ONCOnews #OncoAlert #OncEd #CancerImmunotherapy #NSCLC #ClinicalTrials #Oncology #CancerResearch

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We cover:
• TCR-T, CAR-T, TIL & NK-cell approaches
• Lessons from early clinical studies
• Key biological & practical challenges
• Where the field may be heading next

Will cell therapy work in sarcoma❓

#Sarcoma #CellTherapy #CancerImmunotherapy #TranslationalResearch

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Ultrasmall silica nanoparticles supercharge melanoma immunotherapy – BioNews Central A class of ultrasmall fluorescent silica nanoparticles stimulates the immune system against melanoma, significantly enhancing the effectiveness of cancer immunotherapy. ...

A class of ultrasmall #SilicaNanoparticles stimulates the #ImmuneSystem against #melanoma, significantly enhancing the effectiveness of #CancerImmunotherapy.
#MelanomaImmunotherapy

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