New on the LJI Blog —
Some tumors go into "stealth mode." Here's how scientists are fighting back: bit.ly/4v7lC0d
#Cancer #CancerImmunotherapy #Virology #Health #Medicine
It was a great pleasure to speak two weeks ago at the Annual Meeting of the Portuguese Society of Immunology in Coimbra!
#SPI #Immunology #CancerImmunotherapy
Zelig Eshhar: The Pioneer Who Re-Engineered the T-Cells and Brought CAR-T into the World
dl.begellhouse.com/journals/439...
#CARTCellTherapy #CancerImmunotherapy #TcellEngineering #CRO
🔬Gain new insights into the development and therapeutic potential of engineered EVs. Stay informed with science updates curated for your research interests. ow.ly/T2eb50YxVMl
#CancerImmunotherapy #CancerResearch #Immunotherapy #DrugDelivery #ExtracellularVesicles #BiomedicalResearch
A new class of engineered, supercharged #TCells is stronger, longer-lasting, and more precise at killing #ProstateCancer cells by fine-tuning how they physically interact with #TumorCells.
#ProstateCancerTreatment #CancerImmunotherapy #EngineeredTCells
Harnessing Radiation Effects on the Immune System: Balancing Acts
www.dl.begellhouse.com/journals/2c6...
#RadiationOncology #CancerImmunotherapy #SpatiallyFractionatedRadiation #OT
Watch our on-demand webinar and learn how researchers identified unique #TCR repertoire changes in the peripheral blood of a highly responsive patient following TIL therapy for colorectal cancer.
irepertoire.com/webinars-vid...
#CancerImmunotherapy #CellTherapy
Register now for On Demand Access to @KeystoneSymposia.bsky.social #CancerImmunotherapy : Mechanisms, Clinical Advances and Combinations to explore emerging research! hubs.la/Q0445qFR0 #KSCancerImmune26
Our editor Lise Roth will be attending #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec with @keystoneSymposia.bsky.social
Reach out to talk about your research!
keysym.us/KSCancerImmune26 #KSCancerImmune26
Researchers from the Fourth Military Medical University reported in Cancer Biology & Medicine a comprehensive review examining how gut microbial ecosystems regulate responses to PD-1/PD-L1 immunotherapy.
#Gutmicrobiota #cancerimmunotherapy
Details: doi.org/10.20892/j.issn.2095-3941.2025.0347
We are looking forward to covering this new exciting #CancerImmunotherapy : Mechanisms, Clinical Advances and Combinations meeting, March 15-18 in Québec with @KeystoneSymposia.bsky.social
Take a look at their impressive line-up and register for On Demand: hubs.la/Q0445qFR0
#KSCancerImmune26
MDM2 inhibitors in cancer immunotherapy: Current status and perspective
An overview of MDM2’s role in regulating #CancerImmunotherapy, summarizing preclinical & clinical findings on #MDM2 inhibitors in combination with #Immunotherapy, and highlighting MDM2 inhibition as a therapeutic strategy.
#OpenAccess: doi.org/10.1016/j.ge...
WTF Wire
Cancer immunotherapy time of day may affect survival, with morning treatment linked to better outcomes.
#WTFWire, #CancerImmunotherapy, #CancerResearch, #CancerTreatment, #Immunotherapy, #Oncology, #CancerCare, #MedicalResearch, #HealthNews, #CancerAwareness
www.wtfwire.com/health/cance...
TuHURA Biosciences CEO Dr. James Bianco explains the mechanism of action for the Delta Opioid Receptor which modifies the tumor microenvironment rather than targeting the tumor itself.
$HURA
#ImmunoOncology #CancerResearch #CancerImmunotherapy #ImmuneSuppression #MDSCs
youtu.be/8xSUa9LjsNk
🩸 More insights on bispecific antibody mechanisms and clinical development in Multiple Myeloma
#MultipleMyeloma #BispecificAntibodies #Immunotherapy #CancerImmunotherapy #GPRC5D #FcRH5 #TrispecificAntibodies #AntigenEscape #HemeOnc #HEMEHUB
Abstract deadlines are coming up for the @keystoneSymposia.bsky.social #CancerImmunotherapy meeting this March in Québec.
Learn more about key dates and submission details:
hubs.la/Q03Xlgbv0
#KSCancerImmune26
Honoring Dr. Jewett: Processed osteoclasts effectively "supercharge" NK cells for cancer therapy with faster prep and lower costs.
Free until Feb 15: www.dl.begellhouse.com/journals/2ff...
#NKCellTherapy #CancerImmunotherapy
Explore emerging research with field leaders @keystonesymposia.bsky.social #CancerImmunotherapy : Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03TCrxR0
#KSCancerImmune26
Introducing an albumin-based “Catch-and-Play” platform for rapid assembly of interchangeable T-cell engagers with enhanced in vivo half-life, enabling customizable #TumorTargeting for personalized #CancerImmunotherapy.
#STTT #OpenAccess: doi.org/10.1038/s413...
Promotional image for a Keystone Symposia event titled "Cancer Immunotherapy: Basic Mechanisms Informing Clinical Applications & Combinations," scheduled for March 15-18, 2026, at Fairmont Le Château Frontenac, Quebec, QC, Canada. The background features a winter view of a cityscape with the Château Frontenac visible.
Explore emerging research with field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, this March in Québec! hubs.la/Q03Xlgbv0 #KSCancerImmune26
Two obstacles in #CancerImmunotherapy are tumor-infiltrating T cell exhaustion & mitochondrial dysfunction.
Drs. @yapeng-su.bsky.social & Philip Greenberg at @fredhutch.org & @uwdeptmedicine.bsky.social identified KLHL6 as a dual-negative regulator of both.
Abstract: https://go.nature.com/4qqLAsK
This comprehensive review by Dr. Anahid Jewett and UCLA researchers demonstrates how NK cells select and differentiate cancer stem cells, leading to growth inhibition and reduced metastasis.
Free to read until Feb 15th:
dl.begellhouse.com/journals/2ff...
#NKCells #CancerImmunotherapy
🚀 Join 4 connected Keystone Symposia on #CancerResearch: #Oncogenesis, #TumorMetabolism, #TumorMicroenvironment & #CancerImmunotherapy. Explore breakthroughs from molecular pathways to patients in prevention, detection, treatment & remission. 🔗 keypoint.keystonesymposia.org/home/transfo...
🌐 Explore emerging research w/ field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, March 15-18 in Québec 🏰 JEM's Senior Editor @montse-jexpmed.bsky.social is attending!
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26
🔗 Read more: bit.ly/ONCOnews14J-04
#ONCOnews #OncoAlert #OncEd #CancerImmunotherapy #NSCLC #ClinicalTrials #Oncology #CancerResearch
We cover:
• TCR-T, CAR-T, TIL & NK-cell approaches
• Lessons from early clinical studies
• Key biological & practical challenges
• Where the field may be heading next
Will cell therapy work in sarcoma❓
#Sarcoma #CellTherapy #CancerImmunotherapy #TranslationalResearch
A class of ultrasmall #SilicaNanoparticles stimulates the #ImmuneSystem against #melanoma, significantly enhancing the effectiveness of #CancerImmunotherapy.
#MelanomaImmunotherapy