Home - 14TH ANNUAL MEETING ON CILIA, FLAGELLA AND CENTROSOMES 14TH ANNUAL MEETING ON CILIA, FLAGELLA AND CENTROSOMES

Registrations for our 2026 meeting are now open !
Our 14th meeting on #cilia, #flagella, #centrosome and #ciliopathies to be held September 21-23, 2026, Aussois, France. Visit our website below for program, information, and registration...

www.cfc2026.conferences-pasteur.org/home

Hello everyone, we had a great meeting yesterday @institutimagine.bsky.social , thanks again to all the speakers for their very interesting talks on primary and motile #cilia #flagella #ciliopathies! Next one is organized by Caroline Brun, Marine Laporte, Véronique Morel in Aussois in September!

last paper from the team finally out in CJASN.
#ciliopathies #kidney

journals.lww.com/cjasn/abstra...

Missense Variants in the Second Transmembrane Domain of TMEM17 Disrupt Its Stability and Function and Lead to a Wide Phenotypic Spectrum of Ciliopathies Missense variants in TMEM17 disrupt its localization and function at the ciliary transition zone, leading to a wide range of ciliopathy phenotypes, from OFD6 and Joubert syndromes to Meckel syndrome.

Congratulations to Lucile Boutaud, Sophie Thomas and colleagues @institutimagine.bsky.social ! #cilia #ciliopathies

onlinelibrary.wiley.com/doi/10.1111/...

Our next afternoon meeting is organized by @alexbnmrh.bsky.social on Wednesday March 18 @institutimagine.bsky.social ! Happy to see you soon there...
#cilia #ciliopathies #flagella

Great afternoon with Jihane and Nikita meeting with young French high school students to discuss what we are doing in the @hkd-l.bsky.social lab on #cilia and #ciliopathies as part of the @cilia-ai.bsky.social project!
Many thanks to @cerclefser.bsky.social for the organization of #declics

Let us know when the preprint drops @noelledwyerphd.bsky.social and we can boost here to Clarissa awesome talk- as you could tell by questions, this was a very 🌶️ topic!! #Microtubules #CiliaTip #Stability #Ciliopathies #Neurodevelopment

Two good news today... This work was led by Friederike Petzold in the lab, congrats to all the coauthors!
#kidney #ciliopathies #nephronophthisis

journals.lww.com/cjasn/abstra...

Nice work indeed… among all the interesting findings, quite amazed to see that you can induce the formation of ciliary pockets just by the removal of Arp3! #cilia #ciliopathies #kidney

A superbly synchronized talk from Joy Zheng & Yan Li, from Mu He's lab, Hong Kong Univeristy on airway epithelial-mesenchymal organoids from #hIPSCs for modelling syndromic #ciliopathies. More mature lineages in a dish. Fascinating work on TZ components and motile cilia function. #UKCilia2025 /2

New #organoid research models RPGRIP1-inherited retinal disease; connecting cilium, stress response, and #proteostasis abnormalities to inform variant and therapy assessment. #ciliopathies #AAVtherapy #photoreceptors https://ow.ly/xTwl50Xva6s

University of Sydney (USYD) | ISSCR

Hello everyone, just to announce that our next afternoon symposium on #cilia #flagella and #ciliopathies will take place @institutimagine.bsky.social on Wednesday afternoon March 18 2026. Save the date!

👉Do not miss talks by our coordinator Sophie Saunier and by John Sayer at #KidneyWk 2025 in Houston, TX, the meeting of the @asnkidney.bsky.social - 📅Thursday Nov 6th, 2pm, Room310A - 💊Leading Edge of Therapeutic Development in Cystic Kidney Disease session #NPH #ciliopathies @hkd-l.bsky.social

Advances in ciliary proteomics – towards cracking the hidden proteome code of cilia Summary: This Review explores proteomic strategies for investigating cilia, tracing the evolution from early discoveries to recent advancements enabled by proximity labeling techniques.

📣 Here it is — our overview on ciliary proteomics! Great discussions and writing with @mick-lab.bsky.social and Ronald Roepman 🙏🙏
Hope we didn’t miss anything important - apologies if we did!

#cilia #ciliopathies #proteomics
@theracilproject.bsky.social @for5547.bsky.social

tinyurl.com/yc8ztn5v

In brief, our findings uncover a strikingly conserved #ciliary mechanism in the regulation of chromosomal dynamics in #meiosis, and implicate dysfunction of the zygotene cilium as an overlooked etiology of human #infertility, also expanding the spectrum of #ciliopathies.
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Great Science! Great food and great company in Oberbronn! Thank you to the organizers of the CFC meeting 2025! Thank you for all the fantastic talks & posters! + unbeatable morning runs! @club-cfc.bsky.social @bastinlab.bsky.social @alexbnmrh.bsky.social #cilia #flagella #centrosome #ciliopathies

We have a fabulous finish with @konjikusicmia.bsky.social (@reiterlab.bsky.social, UCSF) on #GPCRs, #signaling, and #hypogonadism in #BBS models across the hypothalamus-pituitary-gonad axes and its many ciliated cell types! #Ciliopathies? www.biorxiv.org/content/10.1... #UKCilia2025 /6

Structure-Activity Analysis Reveals Perturbed Cilia-Jun N-Terminal Kinase Signaling in MAPKBP1-Associated Kidney Disease Nephronophthisis (NPH) is a renal ciliopathy characterized by chronic tubulointerstitial fibrosis. Despite discovery of multiple disease genes, mechanisms of NPH-associated kidney degeneration remain ...

New interesting paper on MAPKBP1, which sheds new light on its localization and function at #cilia! Many thanks to Ria and Jan for inviting us to participate in this exciting work! Congratulations to all collaborators!
#ciliopathies #kidney #nephronophthisis

www.kireports.org/article/S246...

IL1β is induced in nephronophthisis but does not mediate kidney damage

Congratulations to Giulia and Amandine, to other members of the lab and collaborators! Their last paper on IL1-beta in Nephronophthisis is now out in Genes & diseases. #ciliopathies #kidney #inflammation

www.sciencedirect.com/science/arti...

Very happy to find our last article in Kidney International Reports online today!
#cilia #ciliopathies #kidney

Recent article from TheRaCil published in Kidney International Reports by Alice Tata, Guillaume Rocha, Sophie Saunier, Alexandre Benmerah and their colleagues from @institutimagine.bsky.social and collaborators. #cilia #ciliopathies #kidney

Prostaglandin Analogs and Eupatilin as Treatments for Nephronophthisis Primary cilia are sensory antennas that are present on the majority of quiescent vertebrate cells where they mediate key signaling during development …

Our last paper is now available on the Kidney International website! Thanks to all collaborators and special congrats to Alice and Guillaume... #cilia #ciliopathies #kidney

www.sciencedirect.com/science/arti...

We move to magnificent #meiosis #ChromosomalBouquet & #zygotene cilia with Avishag Mytlis (@yanivelkouby.bsky.social lab, Hebrew University, IL) on unpublished work for countering mechanical forces allowing telomere rotation & clustering. Role in human infertility- #ciliopathies? #UKCilia2025 3/7

📣 Don’t miss the review by @bolettalab.bsky.social & S. Clerici on metabolic and mitochondrial alterations in #PolycysticKidneyDisease and other renal #ciliopathies ➡️ doi.org/10.1038/s443...

at IRCCS San Raffaele Scientific Institute

Cilia-AI

9 PhD positions to work on #cilia and #ciliopathies including 2 in our lab @hkd-l.bsky.social @institutimagine.bsky.social

www.cilia-ai.eu

Wow ERN-LUNG PCD core team- what a perfect welcome to Napoli for the 2025 meeting! Room views don’t get much better… ready for a great meeting! Perfect place… #RareRespiratoryDiseases #PrimaryCiliaryDyskinesia #PCD #ciliopathies

Complete loss of IFT27 function leads to a phenotypic spectrum of fetal lethal ciliopathy associated with altered ciliogenesis - European Journal of Human Genetics European Journal of Human Genetics - Complete loss of IFT27 function leads to a phenotypic spectrum of fetal lethal ciliopathy associated with altered ciliogenesis

Here is a recent paper by colleagues from @hopitalnecker.bsky.social and @institutimagine.bsky.social showing that loss of IFT27 lead to fetal #ciliopathies with #cilia defects in #kidney

www.nature.com/articles/s41...

Genetic analysis explains rare disease severity, points to possible treatment Researchers at Washington University School of Medicine in St. Louis have uncovered why some patients with a rare genetic disorder called primary ciliary dyskinesia have worse lung problems than other...

Genetic analysis explains rare disease severity, points to possible treatment 👇 #ciliopathies #PCD

@dutcherlab.bsky.social @brodylab.bsky.social @horanilab.bsky.social @mahjoublab.bsky.social @washu.bsky.social

source.washu.edu/2025/03/gene...

It is #RareDiseaseDay — we'd like to take a moment to raise awareness and support research for rare conditions, including #ciliopathies.

Two PhD positions in our lab for two different projects on #ciliopathies and #cilia