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(like Myelin #Oligodendrocyte #Glycoprotein (MOG)due to structural similarities between these #autoantigens & epitopes of a preceding pathogen.
-50–75% of pediatric cases from post viral infection ( #measles, #mumps, #influenza, rubella, varicella-zoster #COVID.

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Structures of #Marburgvirus #glycoprotein and its complex with NPC1 #receptor

Structures of #Marburgvirus #glycoprotein and its complex with NPC1 #receptor, etidiohnew.blogspot.com/2026/03/stru...

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Here you can see a cryoEM structure of the HCoV-HKU1 glycoprotein D1 Domain, showing its heavy glycosylation pattern (PDB code: 9N17)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #HcoV #HKU1 #glycoprotein #virus

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🤝浩鼎與美國 TegMine Therapeutics 簽訂受其委託開發之醣蛋白 ADC 全球專屬授權合約
🌏此次國際授權合作,展現以浩鼎 Obrion™ ADC 技術所開發產品的應用前景🚀
#OBIPharma #Obrion #GlycOBI #Glycoprotein #ADC #ExclusiveLicense #GlobalPartnership

www.obipharma.com/zh-hant/news...

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Researchers highlight #oncolytic #HerpesSimplexVirus (HSV-1) viruses as promising #CancerImmunotherapies, detailing advances in #glycoprotein retargeting, discussing molecular entry mechanisms, clinical successes, and future challenges.

#OpenAccess: doi.org/10.1016/j.ge...

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genomirx.com/shop/kim-1-p...
Invitrogen, KIM-1 Polyclonal Antibody – PA579345 CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein @invitrogen.bsky.social #kim1 #Polyclonal #Antibody #PA579345 #immunoglobulin #glycoprotein

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Rapid glycoprotein evolution enables variant interactions in herpes simplex virus type 1 Abstract. Glycoproteins cover the surface of enveloped viruses such as herpes simplex virus 1 (HSV-1). Whilst essential for cellular attachment and entry,

New paper alert 🚨
Check out our latest article about #social interactions in #herpesvirus populations via #glycoprotein variants, now in @Virus_Evolution. Thanks to everyone involved, also to the very supportive reviewers who definitely improved the manuscript!
academic.oup.com/ve/article/1...

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A Synthesized Protein From Fish Blood That Could Prevent Food and Drugs From Freezing | Newswise University of Utah engineers’ stripped-down version of glycoproteins in polar-region fish is simple enough to be manufactured at scale, but powerful enough to inhibit formation of ice crystals at sub-...

A Synthesized Protein From Fish Blood That Could Prevent Food and Drugs From Freezing
www.newswise.com/articles/a-s...
#glycoprotein #fishblood #biomedicalengineering

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🍬🔬Proteins are so sweet under the microscope .. 🍬🔬

As Möckl RG, for the first time, we image the single-protein glycosylation in native cell state with super-resolution microscopy, map cell-surface glycoproteins, and uncover their spatial organization.

#MöckIRG
#glycotime
#glycoprotein
#dnapaint

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📢Welcome to read: A Clinical Validation of a Diagnostic Test for Esophageal Adenocarcinoma Based on a Novel Serum #Glycoprotein #Biomarker Panel: #PromarkerEso, by Jordana Sheahan et al.
🔗 mdpi.com/2227-7382/13/2/23
@flindersuniversity.bsky.social
#proteomes #proteomics #proteoforms #MRM-MS

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Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF

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Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF

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Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.

#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF

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A replicating recombinant vesicular stomatitis virus #model for dairy #cattle #H5N1 #influenza virus #glycoprotein #evolution

A replicating recombinant vesicular stomatitis virus #model for dairy #cattle #H5N1 #influenza virus #glycoprotein #evolution, etidiohnew.blogspot.com/2025/06/a-re...

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The re-adenylation phenomenon exhibits substrate specificity - consistently observed in synthetic mRNAs encoding proteins targeted to the #endoplasmic #reticulum (ER), including #spike #glycoprotein, #Zika virus antigens, and #malaria parasitic proteins. (12/n)

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Structure-guided design of a prefusion GPC trimer induces neutralizing responses against LASV - npj Vaccines npj Vaccines - Structure-guided design of a prefusion GPC trimer induces neutralizing responses against LASV

Researchers engineered a stable, prefusion Lassa virus GPC trimer, which, when used as an immunogen in animal models, elicited robust neutralizing antibody responses. www.nature.com/articles/s41... #virology #vaccine #LassaVirus #VaccineDevelopment #Immunology #EmergingViruses #Glycoprotein

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16] Facts About: Major Glycoprotein in Urine – Uromodulin/Tamm-Horsfall Protein (THP)

In our latest interesting fact about #glycans we take a look at the most abundant #glycoprotein found in #urine, and how its glycosylation and function varies under different genetic physiological conditions.

Read more at: research.bidmc.org/ncfg/blog/16...

#glycotime #uromodulin

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The Niemann-Pick C1 (#NPC1) protein is a critical receptor for filoviruses, binding the #filovirus #glycoprotein (GP) to enable viral entry. Variations at the GP-NPC1 interface dictate viral #susceptibility and host range. 4/10

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Mi, Jin, Zhang, Chen, Cui, Chen, Zheng (The Affiliated Taian City Central Hospital of Qingdao University) and Jing (Shandong First Medical University) investigate the role of the #glycoprotein chitinase 3-like 1 in #intestinalischaemia–reperfusion injury.
📜https://buff.ly/3OOTWZY

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Transcriptional reactivation of the tRNASer/tRNATyr gene cluster in Arabidopsis thaliana root tip (V2) Plants retain a repetitious tRNA gene content in their nuclear genome. How important are these individuals, how exactly plants orchestrate their usage, and for what purposes, is poorly understood. Ara...

Don't miss our (updated) work on the developmental regulation of plant nuclear tRNA genes on Bluesky! #RNAsky #TransferRNA #Epigenetic #Chromatin #Tandemrepeat #Cluster #PlantTissue #TissularIdentity #Root #ProteinBiogenesis #Proteostasis #Glycoprotein

www.biorxiv.org/content/10.1...

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CD81 fusion alters SARS-CoV-2 Spike trafficking | mBio The severe acute respiratory syndrome coronavirus 2 pandemic caused the biggest public health crises in recent history. To understand the maturation pathway of S, we fused S to the tetraspanin protein...

. In natural infection, the #SARSCoV2 Spike (S) #glycoprotein is co-expressed with all other viral proteins, which modify cellular compartments to maximize virion assembly.

journals.asm.org/doi/10.1128/...

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