(like Myelin #Oligodendrocyte #Glycoprotein (MOG)due to structural similarities between these #autoantigens & epitopes of a preceding pathogen.
-50–75% of pediatric cases from post viral infection ( #measles, #mumps, #influenza, rubella, varicella-zoster #COVID.
Structures of #Marburgvirus #glycoprotein and its complex with NPC1 #receptor, etidiohnew.blogspot.com/2026/03/stru...
Here you can see a cryoEM structure of the HCoV-HKU1 glycoprotein D1 Domain, showing its heavy glycosylation pattern (PDB code: 9N17)
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #HcoV #HKU1 #glycoprotein #virus
🤝浩鼎與美國 TegMine Therapeutics 簽訂受其委託開發之醣蛋白 ADC 全球專屬授權合約
🌏此次國際授權合作,展現以浩鼎 Obrion™ ADC 技術所開發產品的應用前景🚀
#OBIPharma #Obrion #GlycOBI #Glycoprotein #ADC #ExclusiveLicense #GlobalPartnership
www.obipharma.com/zh-hant/news...
Researchers highlight #oncolytic #HerpesSimplexVirus (HSV-1) viruses as promising #CancerImmunotherapies, detailing advances in #glycoprotein retargeting, discussing molecular entry mechanisms, clinical successes, and future challenges.
#OpenAccess: doi.org/10.1016/j.ge...
genomirx.com/shop/kim-1-p...
Invitrogen, KIM-1 Polyclonal Antibody – PA579345 CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein @invitrogen.bsky.social #kim1 #Polyclonal #Antibody #PA579345 #immunoglobulin #glycoprotein
New paper alert 🚨
Check out our latest article about #social interactions in #herpesvirus populations via #glycoprotein variants, now in @Virus_Evolution. Thanks to everyone involved, also to the very supportive reviewers who definitely improved the manuscript!
academic.oup.com/ve/article/1...
A Synthesized Protein From Fish Blood That Could Prevent Food and Drugs From Freezing
www.newswise.com/articles/a-s...
#glycoprotein #fishblood #biomedicalengineering
🍬🔬Proteins are so sweet under the microscope .. 🍬🔬
As Möckl RG, for the first time, we image the single-protein glycosylation in native cell state with super-resolution microscopy, map cell-surface glycoproteins, and uncover their spatial organization.
#MöckIRG
#glycotime
#glycoprotein
#dnapaint
📢Welcome to read: A Clinical Validation of a Diagnostic Test for Esophageal Adenocarcinoma Based on a Novel Serum #Glycoprotein #Biomarker Panel: #PromarkerEso, by Jordana Sheahan et al.
🔗 mdpi.com/2227-7382/13/2/23
@flindersuniversity.bsky.social
#proteomes #proteomics #proteoforms #MRM-MS
Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.
#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF
Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.
#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF
Top: Schematic of GP2 filaments, with labeled residue ranges of ZP domains and four N-glycosylation sites. Middle left: Cryo-EM map of GP2 filaments, color-coded according to the schematic above. The density of one of the flexible branches was indicated by a black arrow. Middle right: Atomic model of GP2 filaments, with five N-glycosylation sites marked by arrows. Bottom: Proposed model of GP2 filaments’ function in the digestive tract. The filament core of UMOD and GP2 is colored in dark blue and green, respectively. The EGF domains and D8C/D10C domains in the branches of both proteins are shown in grey and light blue, respectively. High-mannose N-glycans are colored in red. UPEC cells and their adhesive pilus are colored in pink, while the proteases (such as elastase) are colored in yellow.
#Glycoprotein 2 (GP2) filaments protect against infections by acting as decoys for the bacterial #lectin FimH. The #cryoEM structure of GP2 filaments provides insights into filament assembly and #antibacterial function in the digestive tract @plosbiology.org 🧪 plos.io/3HP2obF
A replicating recombinant vesicular stomatitis virus #model for dairy #cattle #H5N1 #influenza virus #glycoprotein #evolution, etidiohnew.blogspot.com/2025/06/a-re...
The re-adenylation phenomenon exhibits substrate specificity - consistently observed in synthetic mRNAs encoding proteins targeted to the #endoplasmic #reticulum (ER), including #spike #glycoprotein, #Zika virus antigens, and #malaria parasitic proteins. (12/n)
Researchers engineered a stable, prefusion Lassa virus GPC trimer, which, when used as an immunogen in animal models, elicited robust neutralizing antibody responses. www.nature.com/articles/s41... #virology #vaccine #LassaVirus #VaccineDevelopment #Immunology #EmergingViruses #Glycoprotein
In our latest interesting fact about #glycans we take a look at the most abundant #glycoprotein found in #urine, and how its glycosylation and function varies under different genetic physiological conditions.
Read more at: research.bidmc.org/ncfg/blog/16...
#glycotime #uromodulin
The Niemann-Pick C1 (#NPC1) protein is a critical receptor for filoviruses, binding the #filovirus #glycoprotein (GP) to enable viral entry. Variations at the GP-NPC1 interface dictate viral #susceptibility and host range. 4/10
Mi, Jin, Zhang, Chen, Cui, Chen, Zheng (The Affiliated Taian City Central Hospital of Qingdao University) and Jing (Shandong First Medical University) investigate the role of the #glycoprotein chitinase 3-like 1 in #intestinalischaemia–reperfusion injury.
📜https://buff.ly/3OOTWZY
Don't miss our (updated) work on the developmental regulation of plant nuclear tRNA genes on Bluesky! #RNAsky #TransferRNA #Epigenetic #Chromatin #Tandemrepeat #Cluster #PlantTissue #TissularIdentity #Root #ProteinBiogenesis #Proteostasis #Glycoprotein
www.biorxiv.org/content/10.1...
. In natural infection, the #SARSCoV2 Spike (S) #glycoprotein is co-expressed with all other viral proteins, which modify cellular compartments to maximize virion assembly.
journals.asm.org/doi/10.1128/...