📢 Staining #Peroxisomes in live & fixed cells with Peroxi_SPY probes has never been so easy!
There is now a very detailed #JOVE video that explains it all step by step.
Video link: dx.doi.org/10.3791/6940...
Peroxi_SPY link: spirochrome.com/products/?_c...
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#Pexophagy meets #physiology. In this Spotlight, Michael Clague @liverpooluni.bsky.social discusses recent work by Xiong et al. (rupress.org/jcb/article/...), describing a mouse model to monitor pexophagy dynamics in vivo. rupress.org/jcb/article/...
#ProteinHomeostasis #Peroxisomes #Autophagy
Spotlight: Michael J. Clague @liverpooluni.bsky.social highlights recent work by Xiong et al. (rupress.org/jcb/article/...), describing a mouse model to monitor #pexophagy dynamics in vivo. rupress.org/jcb/article/...
#Physiology #ProteinHomeostasis #Peroxisomes #Autophagy
Spotlight: Michael J. Clague @liverpooluni.bsky.social highlights recent @jcb.org study by Xiong et al. (rupress.org/jcb/article/...), describing a mouse model to monitor #pexophagy dynamics in vivo. rupress.org/jcb/article/...
#Physiology #ProteinHomeostasis #Peroxisomes #Autophagy
Xiong, Gao, Wu et al. present new mouse models for visualizing the selective degradation of #peroxisomes (#pexophagy) in living animals. rupress.org/jcb/article/...
Dinner with the group afterward was a great way to continue the conversation.
#Peroxisomes #CellBiology #ASCB2025 #CellBio2025
Reevaluating the roles of PPARs and nuclear receptors in human #peroxisome biology. New Viewpoint from Fred Mast (@fredmast.bsky.social), Richard Rachubinski, and John Aitchison @seattlechildrens.org: rupress.org/jcb/article/...
#Organelles #Development #Metabolism #CellSignaling #Peroxisomes
Core #biochemical interactions among #H2O2, •NO, and H2S in plant #peroxisomes that modulate #CAT activity.
www.sciencedirect.com/science/arti...
#PlantScience @plantredox.bsky.social #Agriculture #ROS #Redox
Viewpoint: @fredmast.bsky.social, Rachubinski, and Aitchison @seattlechildrens.org challenge the PPAR paradigm and show human #peroxisomes expand via hominid-specific pathways that link specialization to immunometabolic functions. rupress.org/jcb/article/...
#Organelles #Development #Metabolism
Viewpoint @jcb.org: @fredmast.bsky.social, Rachubinski, and Aitchison @seattlechildrens.org challenge the PPAR paradigm and show human #peroxisomes expand via hominid-specific pathways that link specialization to immunometabolic functions. rupress.org/jcb/article/...
#Organelles #Development
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce #pexophagy, say Hongli Li, Marc Fransen and colleagues (KU Leuven): rupress.org/jcb/article/...
#Biochemistry #Organelles #Autophagy #Peroxisomes
Hongli Li, Marc Fransen et al. identify PEX14 as a key link between optineurin and the autophagic machinery in #pexophagy, the selective degradation of #peroxisomes. This discovery advances our understanding of #peroxisome clearance and disease. rupress.org/jcb/article/...
#Autophagy #Organelles
In @jcb.org, Hongli Li, Marc Fransen et al. identify PEX14 as a key link between optineurin and the autophagic machinery in #pexophagy, the selective degradation of #peroxisomes. This discovery advances our understanding of #peroxisome clearance and disease. rupress.org/jcb/article/...
#Autophagy
Your first sole-author review is a big milestone for any scientist! 🙌
For Ruth Carmichael of @exeter.ac.uk it was a chance to shine a spotlight on the peroxisome. 🔬👩🔬
Read about her review & her experience of writing solo: ow.ly/r1yK50X5uZH
#soleauthorreview #soleauthor #peroxisomes #organelle
🔥Hot Off the Press | Nature: Peroxisomes fuel heat
Brown fat cells use peroxisomal β-oxidation of branched fatty acids (mmBCFAs) via ACOX2 → UCP1-independent thermogenesis.
Key to cold tolerance & obesity resistance.
🧐Read more: www.nature.com/articles/s41...
#Metabolism #Peroxisomes #Nature
Thrilled to be heading to Spain next week to speak at the EMBO Workshop on Peroxisomes! 🧫🔬👩🔬
Looking forward to sharing our latest research and learning from incredible scientists working on these fascinating organelles.
#peroxisomes #EMBOmeeting #cellbiology
meetings.embo.org/event/25-per...
Researchers have now discovered how many #peroxisomes (an organelle which breaks down toxins and makes vital molecules) a cell needs is regulated by an enzyme called PKC. Explore the research ➡️ https://bpod.org.uk/archive/2025/08/12
Image made with Leica Microsystems microscopy.
Major part of my PhD thesis is finally online! Thanks to everyone involved 🙏 @walterwchen.bsky.social @rjdlab.bsky.social @tmoeckli.bsky.social @hirakdas.bsky.social and the entire @warscheidlab.bsky.social #peroxisomes #Massspec #proteomics
Like a relay racer: The protein PEX39 (purple) carries enzymes (yellow) like a baton to the peroxisomes. There, the cargo is transported through the membrane by another PEX protein. (Image: Daniel Wendscheck / University of Würzburg)
#Biochemistry: #PEX39, a newly discovered #peroxin protein, transports enzymes into #peroxisomes like a relay racer. New paper @natcellbio.nature.com – congratulations to @dwendscheck.bsky.social @warscheidlab.bsky.social et al!
➡️ www.uni-wuerzburg.de/en/news-and-...
Excited to receive an NIH K08 Clinical Investigator Award to support my research on #mitochondria #peroxisomes 😀 The $775K will be critical in helping me transition to independence as I begin looking for a place to start my lab 🙏🏻 @the-asci.bsky.social
What a beautiful biochemical workout on dehydrogenases studies towards FAO & localization.
Imagine ACAD10/11 co- & post-translational modifications gloriously changing. :) Congrats, @edreesrashan.bsky.social.
#metabolomics #cryoem #notredundant #fattyacids #peroxisomes #mitochondria
Honored to receive @bwfund.bsky.social Career Award for my research on #mitochondria #peroxisomes and be 1st neonatologist awardee! The $700K for starting my lab will enable exciting research on #organelles #metabolism to help medicine’s smallest patients. #neonatal www.bwfund.org/news/bwf-ann...
Missed a few talks (had to go to another meeting). Got back in time to see Tom Hobman from @ualberta.bsky.social presenting their work on how #peroxisomes are involved in RNA virus infection
Here we see Peter Kim, as he reminisces about Rick Rachubinski's time at McMaster,the evolution of models of peroxisome biogenesis, as well presenting their current work on #peroxisomes
Francesca DiCara, who worked with Rick Rachubinski while a post-doc in #CellBiology @ualberta.bsky.social is presenting their work on immno-metabolism regulation by #peroxisomes in flies and mammals.
Fred Mast - graduate of the @ualberta.bsky.social #CellBiology undergraduate program and former PhD student with Rick Rachubinski tells up about kinases that regulate human #peroxisomes
Suresh Subramani, longtime collaborator of the Rachubinski lab gets us going with the first talk today. @ualberta.bsky.social #CellBiology #peroxisomes
It's bittersweet as we start a day-long symposium at @ualberta.bsky.social #CellBiology to honor the career and retirement of Rick Rachubinski. #peroxisomes
Check out this interesting study on intercellular transport of damaged mitochondria and peroxisomes via tunneling nanotubes. #TNTs #academicresearch #sciencecomm #mitochondria #cell #transfer #peroxisomes #academicchatter
www.sciencedirect.com/science/arti...
Our lungs rely on alveolar macrophages (AMs) for health. The Koch lab @ethz.ch reports on @cellpress.bsky.social that AMs need #peroxisomes to handle toxic fats, energy, #mitochondrial fitness & lung #immunity. Peroxisomes are vital for lung defense. More: biol.ethz.ch/en/news-and-...
