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A comprehensive overview of signaling pathways in colorectal cancer, spanning pathogenesis to targeted therapy.
A roadmap for translational research.
doi.org/10.1038/s413...
#ColorectalCancer #SignalTransduction #CancerPathogenesis #TargetedTherapy #OncologyReview

Colon cancer research is advancing across clinical trials, tumor biology, metabolism, immunity and single-cell genomics.
Explore the latest discoveries from Signal Transduction and Targeted Therapy:
www.nature.com/sigtrans/
#ColonCancer #ColorectalCancer #SignalTransduction #TargetedTherapy

#Phosphoinositides show dynamic patterns that shape membrane identity and signaling. This review covers their organization in well-studied and understudied organelles — ER and nucleus — and why spatial control matters for #CellBiology, #SignalTransduction and #Disease. 👨‍🔬🔬

doi.org/10.1002/1873...

AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic #bradycardia. New study from Luca M.G. Palloni, Dario DiFrancesco and colleagues (University of Milano): rupress.org/jgp/article/...

#MolecularPhysiology #CellularPhysiology #CardiacMuscle #SignalTransduction

On the occasion of the International Day of Women and Girls in Science, the #STS is celebrating our three female STS Medal Award winners as representatives of women in #SignalTransduction!

Diabetes research highlights from Signal Transduction and Targeted Therapy, spanning disease mechanisms, complications, and emerging therapeutic strategies.
www.nature.com/sigtrans/
#DiabetesResearch #MetabolicDisease #SignalTransduction #TranslationalMedicine

Redirecting

🧬 Just published online in JPS❣️ (📖 Open Access!! 03 February 2026)
“Identification of a Small Molecule that Targets Activator of G-protein Signaling 8”
— Alamgir Hossain et al.
🔗 doi.org/10.1016/j.jp...
#GPCRsignaling #SmallMolecule #SignalTransduction #NowOnline #JPhysiolSci

Lung cancer research highlights from Signal Transduction and Targeted Therapy, featuring advances from molecular pathology to clinical trials and therapeutic resistance.
www.nature.com/sigtrans/
#LungCancer #CancerResearch #SignalTransduction #TranslationalMedicine

Reverse-engineering B-Arrestin Bias in the d-Opioid Receptor
de Fabritiis, G. et al.
Paper
Details
#BArrestinBias #dOPioidReceptor #signaltransduction

Gastrointestinal cancer: molecular pathogenesis and targeted therapy - Molecular Biomedicine Gastrointestinal (GI) cancers pose a significant global health burden, driven by complex molecular alterations and microenvironmental interactions. Advances in molecular pathogenesis have elucidated r...

#Review
Gastrointestinal cancer: molecular pathogenesis and targeted therapy doi.org/10.1186/s435...

#GastrointestinalTumor #Immunotherapy #TargetedTherapy #SignalTransduction

Cell–cell communication shapes development, immunity, and disease. A broad synthesis of signaling modes and clinical implications.
#CellCellCommunication #Immunology #SignalTransduction #DevelopmentalBiology
www.nature.com/articles/s41...

Share your latest discoveries in immunology, molecular signaling, and targeted therapy.
#Immunology #CellBiology #SignalTransduction
Submit to Signal Transduction & Targeted Therapy: mts-sigtrans.nature.com

Exploring new frontiers in molecular and cell biology—from cell-cycle fidelity to redox control, metastasis, and therapeutic innovation.
Thread
Discover the latest research at Signal Transduction & Targeted Therapy:
www.nature.com/sigtrans/
#Immunology #CellBiology #SignalTransduction

Cardiomyocyte Rac1 signaling in hypertrophy, arrhythmia, and cardiac stress adaptation Cardiovascular disease remains the leading cause of mortality globally and is often marked by pathologic cardiac remodeling including hypertrophy and …

🧪 Just out: a new #review of Rac1-driven signalling in cardiomyocytes — covering #hypertrophy, #arrhythmia and #redox stress.

A must-read for anyone in cardiac research! 💙

#Cardiology #HeartResearch #SignalTransduction #CardioSky

www.sciencedirect.com/science/arti...

We’re excited to be attending the Signal Transduction Society (STS) Meeting, taking place November 3–5, 2025, in Weimar

If you’re here, stop by our booth to learn how our antibodies, kits, and recombinant proteins can support your research

#SignalTransduction

www.youtube.com/watch?v=jtUL...
Revvity HTRF Human Total IRAK4 Detection Kit | Advanced Protein Analysis | Available at @GenomiRX.bsky.social
@revvity.bsky.social #HTRF #IRAK4DetectionKit #GenomiRX #ProteinAssay #BiotechResearch #SignalTransduction #KinaseAssay #ImmunologyResearch #MolecularBiology

#SUMOylation and an ATS1 variant converge to disrupt PIP₂-dependent gating of Kir2.1, say Aishwarya Chandrashekar, Leigh Plant and colleagues @nubouve.bsky.social: rupress.org/jgp/article/...

#Pathophysiology #IonChannels #SignalTransduction #CellularPhysiology #MolecularPhysiology

Meeting 2025 | STS

Abstract submission deadline for the #STS meeting on #SignalTransduction extended to 𝟯𝟬𝘁𝗵 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿. Great line-up of speakers with Hao Wu of Boston Children's Hospital delivering the #STS Honorary Medal: sigtrans.de/meeting-2025 | Weimar, 3-5 November

Last week, CSI Singapore hosted Dr. Michel Steinmetz from @psich.bsky.social. He spoke on the topic “Microtubule-mediated Signal Transduction and Interactions with Anticancer Drugs”.

#CancerResearch #Oncology #CancerScience #OncologyResearch #Microtubules #SignalTransduction #CancerBiology

IPI Events Calendar Learn how Google Calendar helps you stay on top of your plans - at home, at work and everywhere in between.

Pengxiang Huang of @bcmhouston.bsky.social‬ joins us for our next #IPISeminar today at 2 p.m. EST to share work on #signaltransduction in the #Hedgehog & #Wnt pathways! Follow the QR Code below or find the Zoom link on our calendar ➡️ rb.gy/xcee9l #neuroskyence #proteinscience

🧬The next talk in our GBM Lunch series will be given by Ingrid Fleming (Frankfurt), who will present her research on "Lipid mediators of vascular signaling"
🗓 Date: June 4, 2025
🕒 Time: 12:30 – 13:30 (CEST)
Chair: Antje Ebert (Göttingen)
#GBMLunch #SignalTransduction
Übersetzung anzeigen

Registration is OPEN for the 28th Signal Transduction Society Meeting—first-ever #CellCommSummit!
🗓️ November 3–5, 2025, Leonardo Hotel, Weimar
Join us for talks, poster sessions, and networking. Travel grants for young researchers available.
🔗 www.sigtrans.de
#SignalTransduction #CellCommSummit

A new study introduces the Gαi bONE-GO biosensor, a powerful tool for visualizing native GPCR signaling and uncovering hidden dynamics like partial agonism of opioid neuropeptides #Pain #GPCRs #Signaltransduction #GαibONE-GO www.science.org/doi/full/10....

🧬 Targeting conserved #TranscriptionFactors to prevent #tumour growth: Baker, Shah, and colleagues provide a high-throughput method for identifying novel ETS inhibitors, and characterise candidate molecules

➡️ doi.org/10.1002/1873-3468.70040

#angiogenesis #signaltransduction #cancerbiolgy

congratulations greeting card with a group of hands ALT: congratulations greeting card with a group of hands

Huge congrats to the 2025 Cole Award winners from @biophysicalsoc.bsky.social to
@Baron Chanda
@Daniel Minor
@Crina Nimigean

#ionchannels #biophysics #electrophysiology #membranes #signaltransduction #science #scientists

Finally here: #CellSignaling by Wendell A. Lim and Bruce J. Mayer - an excellent and comprehensive resource for researchers, lecturers, and students interested in #SignalTransduction. A perfect Christmas present for self?

Registration is open for a #Canadian classic. Signalling in Normal & Cancer Cells. #Science4All #ScienceSaves #ScienceIsFun #SignalTransduction #scRNAseq #ModelSystems #kinases #oncogenes #cytoskeleton #CellCycle #Chromatin #epigenetics
@cdnwomenstem.bsky.social

event.fourwaves.com/banffsncc202...