"IBS is a group of intestinal symptoms that typically occur together. The symptoms vary in severity and duration from person to person."

#IrritableBowelSyndrome #InflammatoryBowelDisease #GastrointestinalDisorders

www.healthline.com/health/irrit...

Site Network for IBD Trials | Docwire News Laurent Peyrin-Biroulet, MD, PhD, describes the results of a study evaluating use of a site network to improve enrollment for IBD trials.

Professor Laurent Peyrin-Biroulet discusses a study evaluating use of the Iterative Health site network to improve enrollment for #InflammatoryBowelDisease trials. #IBDSky #GISky
📹 Watch the full interview at the link!

www.docwirenews.com/post/improvi...

Discovery of a Colon-Targeted Prodrug As an Escherichia coli Biofilm Inhibitor for Treating Inflammatory Bowel Disease We hypothesized that the formation of biofilms contributes to the onset of inflammatory bowel disease and, thus, attempted to develop biofilm inhibitors as potential treatment options. We identified a...

Discovery of a Colon-Targeted Prodrug as an Escherichia coli Biofilm Inhibitor for Treating Inflammatory Bowel Disease

pubs.acs.org/doi/10.1021/... @pubs.acs.org

#MedicinalChemistry #DrugDiscovery #ProdrugDesign #InflammatoryBowelDisease #Pharmacology #Therapeutics #GutHealth #DrugDevelopment

Three selfies of New lying on the floor in My Little Pony pajamas, looking OVER IT (doing nightly colitis meds)

eNeMa (-᷅_-᷄๑)

#spoonie #ulcerativecolitis #inflammatoryboweldisease #colitis #spoonie #disability #mesalamine

Antibiotics can leave a long-term footprint on our gut microbiome: study A study reveals that certain antibiotics can cause long-lasting changes in gut microbiome diversity for up to eight years.

#Antibiotics can leave a long-term footprint on our #GutMicrobiome —changes last for 4 to 8 years after treatment

#LowerDiversity of #GutMicrobiomeSpecies has been associated with a range of #HealthConditions, such as #obesity, #diabetes, & #InflammatoryBowelDisease
www.thehindu.com/sci-tech/hea...

Propel a Cure has announced a new grant opportunity to support impactful Crohn’s disease research! Learn more about this important funding opportunity and how to apply by visiting their website: www.propelacure.org/grants

#crohns #ibd #inflammatoryboweldisease

Maternal mid-pregnancy dietary patterns and inflammatory bowel disease in offspring from a prospective cohort study - Communications Medicine Anneberg et al. investigate associations between data-driven maternal dietary patterns during pregnancy and offspring’s risk of inflammatory bowel disease (IBD). Based on 56,097 mother-child pairs followed over 18 years, they show that a diverse dietary pattern may protect offspring against IBD development compared to a Western dietary pattern.

🚨 NEW RESEARCH! ⚕️ 🩺

Anneberg et al. examined maternal dietary patterns during pregnancy and their associations with pediatric-onset IBD risk in offspring.

http://dlvr.it/TRRqyl #InflammatoryBowelDisease #DietaryPatterns #MaternalHealth

Risankizumab for Heavily Pretreated CD | Docwire News Real-world data showed 60% of patients with heavily pretreated Crohn’s disease who received risankizumab achieved steroid-free clinical remission by week 12.

In a large real-world study, more than 60% of patients with #CrohnsDisease treated with #risankizumab achieved steroid-free clinical remission by week 12, and through 1 year of treatment.
#Gastroenterology #GISky #inflammatoryBowelDisease #IBDSky

Delivery Route of FMT: Colonic vs Nasogastric | Docwire News Colonic delivery of fecal microbiota transplantation was a more effective route than nasogastric administration for patients with ulcerative colitis.

Colonic delivery of #FecalMicrobiotaTransplantation was a more effective route than nasogastric administration for patients with #UlcerativeColitis.
#Gastroenterology #InflammatoryBowelDisease #IBDSky #GISky #FMT

Research Article

Risk of Spondyloarthritis in Patients With Inflammatory Bowel Disease Receiving Treatment With Biologics or Janus Kinase Inhibitors

📖 www.jrheum.org/cgi/content/...

#CrohnDisease #UlcerativeColitis #InflammatoryBowelDisease #Spondyloarthritis

Editorial

Evaluation of Emergent Musculoskeletal Symptoms in Patients With Inflammatory Bowel Disease: How Does Imaging Help?

📖 doi.org/10.3899/jrhe...
@ualberta.bsky.social

#InflammatoryBowelDisease #Spondyloarthritis

Schematic diagram of the ACSS2-H3K9cr axis in delaying senescence and improving the function of Adipose-derived mesenchymal stem cells (ADSCs)

Cell Regen Research | Lysine crotonylation delays adipose-derived mesenchymal stem cell senescence & boosts efficacy in IBD! NaCr restores Kcr, suppresses NF-κB, and enhances anti-inflammatory effects in colitis models. #StemCells #InflammatoryBowelDisease
🔗 Full paper at: doi.org/10.1186/s136...

A graphic promoting the Crohn's & Colitis Foundation IBD Pro Visiting IBD Observership. It includes a testimonial highlighting the learning experience. The deadline to apply is extended to February 27.

#GIfellows: Funded observership. 1 month. High-volume #IBD center.

One more week to apply! https://bit.ly/3tRNGKf

Not a #Gastroenterology fellow? Spread the word! #MedicalEducation #FellowshipOpportunity #crohns #ulcerativecolitis #inflammatoryboweldisease

Tolerability of GLP-1 RAs in IBD | Docwire News For patients with IBD, GLP-1 receptor agonists provided benefits in weight loss and metabolic improvements without exacerbating IBD symptoms.

#GLP1 receptor agonists may be a safe and beneficial option for managing #obesity and metabolic comorbidities for adults with #InflammatoryBowelDisease.
#GISky #IBDSky

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling, offering new therapeutic strategies for inflammatory bowel disease.
doi.org/10.1038/s413...
#InflammatoryBowelDisease #TCells #ExtracellularVesicles #PD1 #Immunotherapy

A simple blood test can predict Crohn’s disease before symptoms appear.
https://ow.ly/kM2Q50YbXqH
#CrohnsDisease #IBDAwareness #InflammatoryBowelDisease #GutHealth

Intermittent fasting cut Crohn’s disease activity by 40 percent and halved inflammation in randomized clinical trial – BioNews Central A new randomized controlled study found that time-restricted feeding—a form of intermittent fasting—significantly reduced symptomatic disease activity and systemic inflammation in overweight or obese adults with Crohn’s disease. ...

A new randomized controlled study found that #TimeRestrictedFeeding — a form of #IntermittentFasting—significantly reduced symptomatic disease activity and systemic #inflammation in #overweight or #obese adults with #CrohnsDisease
#InflammatoryBowelDisease

Abominable Abdominal Adhesions Out of hospital Going into reverse narrative here, as befits the evolution of how I came to have an emergency admission for severe dehydration, consequent to a partial small bowel obstruction; born…

msmartinecom.wordpress.com/2026/02/08/a... My recent #hospitalisation for partial #smallbowelobstruction due to #adhesions #crohns #inflammatoryboweldisease #multiplesclerosis #blog ⁦‪

A novel dark borosilicate oral contrast agent has shown improved visualization of bowel anatomy in CT imaging.

In a pilot study from @uwdeptmedicine.bsky.social, this new agent significantly improves visualization of #InflammatoryBowelDisease and abdominal cancer.

🔗 https://bit.ly/4qe7ONS

TL1A Promotes Fibrogenesis in Colonic Fibroblasts via the TGF-β1/Smad3 Signaling Pathway

TL1A promotes #IntestinalFibrosis by inducing TGF-β1-mediated intestinal fibroblast activation, proliferation, and collagen deposition via TGF-β1/Smad3 pathway, highlighting a critical #TherapeuticTarget for #InflammatoryBowelDisease
Read: doi.org/10.1007/s115...

Investigadoras do i3S inovam no estudo das doenças inflamatórias do intestino Sofia Barros e Inês Alves vão receber duas ECCO Grant de 80 mil euros para desenvolverem projetos focados na Doença de Crohn e outras doenças

PROJECTS & INNOVATION 💡
The #i3S researchers Sofia Barros and Inês Alves have been awarded two ECCO Grants, each worth 80,000€, to develop innovative projects in the fields of #Crohn’s disease and #InflammatoryBowelDisease.

Well done, Sofia and Inês! 👏

Help us make the invisible visible! 📢 #IBDSuperHeroes is on a mission to raise awareness and stamp out the stigma of #InflammatoryBowelDisease.

Check out our #IBDawareness resources for images and info you can share: tinyurl.com/IBDSHAwareness 💜

#Crohns #Colitis #IBD

GLP-1RAs for IBD | Docwire News Use of GLP1 receptor agonists was associated with improved inflammatory bowel disease-related outcomes.

Real-world data presented at #CCCongress26 suggest GLP-1 receptor agonists may improve #InflammatoryBowelDisease outcomes. In IBD, #GLP1 RA use was linked to lower steroid use, hospitalizations, surgery, and mortality, supporting further study. #GISky #IBDSky

Targeting IL-23 in IBD Management | Docwire News IL-23 drives chronic inflammation across IMIDs. Targeted IL-23 inhibitors are reshaping IBD care with durable efficacy, mucosal healing, and favorable safety.

IL-23 is a key driver of chronic inflammation across the gut-skin-joint axis, transforming #InflammatoryBowelDisease care. IL-23 targeted therapy show durable efficacy, mucosal healing, and favorable safety, supporting earlier use in IBD treatment. #IBDSky #GISky

Scientists identify #EpothiloneB as a repurposed therapy for #InflammatoryBowelDisease, showing it promotes epithelial repair, reduces #inflammation, rebalances #GutMicrobiota, and induces #neutrophil #apoptosis using #zebrafish screening.

#OpenAccess: doi.org/10.1016/j.ge...

A new diet option for mild-to-moderate Crohn’s disease – BioNews Central A national, randomized controlled clinical trial found that a short-term, calorie-restrictive diet significantly improved both physical symptoms and biological indicators of mild-to-moderate Crohn’s disease. ...

A national, #RandomizedControlledTrial found that a short-term, #CalorieRestrictiveDiet significantly improved both physical symptoms and biological indicators of mild-to-moderate #CrohnsDisease.
#InflammatoryBowelDisease #Fasting #FastingMimickingDiet

Have you been using #AI to support your #InflammatoryBowelDisease management, another condition, or your overall health?

How do you use it, and what has and has not been useful?

#PatientAdvocate #IBDSuperHeroes #Crohns #Colitis #IBD #CrohnsDisease #UlcerativeColitis #IBDawareness #IBDVisible

What Changes in the Gut Microbiome Occur at the Onset of Inflammatory Bowel Disease? At the onset of inflammatory bowel disease, the gut microbiome shows a clear loss of beneficial, obligate anaerobic bacteria that help digest complex carbohydrates, and a rise in oxygen-tolerant bacteria, including species that normally live in the mouth. These shifts were detected in newly diagnosed people with Crohn’s disease and ulcerative colitis before any treatment, across a combined dataset of more than 1,700 participants from 11 countries.

At IBD onset, helpful anaerobes fade while oxygen-tolerant microbes surge—reshaping the gut ecosystem. Could early interventions target this shift? #CrohnsDisease #InflammatoryBowelDisease #Microbiome #OxygenHypothesis #UlcerativeColitis

New white paper from the PROMISE Consortium outlines a research roadmap for predicting and preventing inflammatory bowel disease (IBD), drawing on insights across genomics, the microbiome, immune biology, and environmental factors.
www.sciencedirect.com/science/arti... #InflammatoryBowelDisease

Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease

A #bioengineered #ExtracellularVesicle therapy with #PDL1 and #miR27a3p reprograms T‑cell immunity in #InflammatoryBowelDisease by suppressing Th17 #bioenergetics, expanding #Tregs, reducing inflammation, and preserving gut epithelial integrity.

#STTT: doi.org/10.1038/s413...