New study from Linköping University in #Sweden shows how to disrupt the interaction between “undruggable” N-MYC and Aurora A in #neuroblastoma. #drugdiscovery #innovation www.linkedin.com/posts/drmelv...

New study in Nature Metabolism shows #fructose isn’t just calories - it’s a metabolic signal that drives #fat production, lowers cellular energy, and may contribute to #obesity & #metabolicdisease.
www.linkedin.com/posts/drmelv...

🔬NEW study (RIKEN Center for Integrative Medical Sciences) links: #BRCA1 → #thyroidcancer and #BRCA2 → #bladdercancer, #skincancer, head & neck #cancer
A step toward extending #precisionmedicine beyond common cancers. #BRCA #Oncology #CancerResearch
www.linkedin.com/posts/drmelv...

New research suggests #mpox #outbreaks can shift over time from sexual transmission among adults to household/community spread that increasingly affects children. Surveillance + #vaccination strategies need to adapt as transmission patterns change. www.linkedin.com/posts/drmelv...

A study in Nature #Microbiology links covert mortality nodavirus (CMNV) - found in #shrimp / #fish - to rising #eye #infections in China. Risk factors: handling raw #seafood + eating it uncooked. #OneHealth
www.linkedin.com/posts/drmelv...

#Measles is NOT harmless - it can be dangerous and even deadly, especially for young children. A reminder of why #vaccination matters. #VaccinesSaveLives #VaccinesWork www.linkedin.com/posts/drmelv...

New research from #McGill @mcgilluniversity.bsky.social identifies HSPE1 as a key vulnerability in #pancreaticcancer. Blocking two survival pathways simultaneously significantly slows #tumor growth offering a promising new combination therapy strategy. www.linkedin.com/posts/drmelv...

#Oralhealth is not separate from systemic health. New research from University of Cincinnati College highlights a bidirectional link between periodontal disease and #chronickidneydisease, driven by #inflammation, immune dysfunction & microbial #dysbiosis. www.linkedin.com/posts/drmelv...

Promising new approach from @mskcancercenter.bsky.social : uPAR-targeted #CARTcells tackle both #tumor cells and their microenvironment, showing strong preclinical activity in solid #tumors and #metastases. www.linkedin.com/posts/drmelv...

Your #gut may play a bigger role in #brainhealth than we thought. New research shows #diet, #probiotics & even #FMT can improve cognition especially early on. The gut-brain axis might be key to slowing #AlzheimersDisease #AD and #dementia. #GutHealth www.linkedin.com/posts/drmelv...

Stronger evidence now links #vaping to #cancer risk before long-term data arrives. We shouldn’t repeat the delays seen with #smoking. www.linkedin.com/posts/drmelv...

New @yorkuniversity.bsky.social study: how to contain #H5N1 #birdflu if human-to-human transmission begins
1) Early action > reactive response
2) Pre-emptive > reactive #vaccination
3) Isolation critical, but asymptomatic spread is a risk. #PandemicPreparedness
www.linkedin.com/posts/drmelv...

New #COVID #variant “#Cicada” (BA.3.2) is spreading, but not more severe so far. The real concern? Its ability to evade #immunity.vNot panic, but a good reminder that #SARSCoV2 is still evolving and worth paying attention to. www.linkedin.com/posts/drmelv...

New research from @umcutrecht.bsky.social & @amsterdamumc.bsky.social shows #longCOVID may be driven by #autoantibodies. Patient IgG triggered persistent pain symptoms in mice (even years later) highlighting a lasting, immune-driven mechanism. #COVID #immunology www.linkedin.com/posts/drmelv...

#HIV overactivates the #immunesystem, causing long-term dysfunction. New research from Linköping University @liu.se shows the #lupus drug #anifrolumab may restore immune cell function, opening the door to immune repair strategies alongside antivirals. #Immunology www.linkedin.com/posts/drmelv...

This study from Duke-NUS and @bristoluni.bsky.social highlights how tissue-specific #immunity in the #skin can shape #denguefever disease outcomes and points to a new generation of #dengue #vaccines designed to target immune responses at the site of #infection. www.linkedin.com/posts/drmelv...

#Ticks are active from 4°C and can carry several diseases. As #tickborne risks grow more complex, prevention matters more than ever: protective clothing, repellent, #tick checks, prompt removal, and #vaccination where available. #TickBitePreventionWeek www.linkedin.com/posts/drmelv...

Promising early results for MK-7602, a dual-action #antimalarial from @wehi-research.bsky.social & #MSD (Merck & Co., Inc.) show strong tolerability and potential to tackle #drugresistance. A major step forward in global #malaria #drugdiscovery + #innovation. www.linkedin.com/posts/drmelv...

Exciting new research from @jacksonlab.bsky.social: PD-L1 can play opposite roles depending on context - suppressing anti-tumor #immunity while enhancing #antiviral defense. Big implications for both #cancer therapy and #infectiousdisease www.linkedin.com/posts/drmelv...

If #vaccines like #Shingrix are associated with reduced risks of #dementia and cardiovascular events, it challenges the way we traditionally assess their impact. www.linkedin.com/posts/drmelv...

A #publichealth alert has been issued after a deadly #meningitis #outbreak in #Kent, with health workers across England urged to watch for signs of infection. I’m resharing this important TED-Ed 2018 video to help spread awareness. Please watch and share. www.ted.com/talks/melvin...

The #meningitis #outbreak at the University of Kent is a reminder that #infectiousdiseases don’t wait - rapid response and prevention systems matter more than ever. Universities remain high-risk environments without strong #vaccination coverage. #VaccinesWork www.linkedin.com/posts/drmelv...

A smart shift toward metabolic vulnerabilities in #tuberculosis #TB - exactly the kind of #innovation needed to tackle #antimicrobialresistance #AMR #drugresistance. Promising research for next-gen antibiotics from @imperialcollegeldn.bsky.social + @lshtm.bsky.social www.linkedin.com/posts/drmelv...

Exciting engineered bacterial #drugdelivery research from @baylor.bsky.social. Turning #bacteria into drug couriers is a bold and promising leap for #cancer therapy. Targeted intracellular delivery like this could redefine how we treat hard-to-reach #tumors. www.linkedin.com/posts/drmelv...

Smart pivot: using #immunecell behavior instead of chasing #tumor cells. Leukocyte adhesion as a signal for relapse + #chemotherapy treatment response is a big step toward real-time #cancer monitoring. www.linkedin.com/posts/drmelv...

Circular RNAs were often considered unimportant byproducts. But this new @yaleschoolofmed.bsky.social study shows that #HIV actually produces a circular RNA called #circHIV, which helps the #virus activate its genes and replicate more efficiently. www.linkedin.com/posts/drmelv...

Sweating while pumping #gas
Nauseous when the total #GasFees shows.
Diagnosis: #Carownervirus 🚗⛽️

Targeting KRAS-driven precancerous pancreatic lesions before #tumors form could redefine early intervention strategies for pancreatic ductal adenocarcinoma PDAC - one of the deadliest #cancers. Important work from @pennmedicine.bsky.social Abramson Cancer Center www.linkedin.com/posts/drmelv...

I am starting a serious journey into #AI. Just completed #ArtificialIntelligence: Implications for #BusinessStrategy from #MITSloan. This is only the beginning. There’s a lot more to learn. Excited to explore how AI can transform #healthcare and #globalhealth. www.linkedin.com/posts/drmelv...

New study showing how Enterococcus faecalis suppresses immune signaling in wounds using lactic acid. Chronic #infections may persist not just because of #antibiotic resistance, but because the #immune response is muted. www.linkedin.com/posts/drmelv...