#MPB
Macleaya cordata's medicinal alkaloids boost livestock growth & gut health. Genomics & synthetic biology now enable sustainable, scalable production.
Details: maxapress.com/article/doi/10.48130/mpb...
#MacleayaCordata #Alkaloids

#MPB
Review explores strategies to boost medicinal benzylisoquinoline alkaloid (BIA) production in plants & microbes, key for developing new plant-based drugs.
Details: maxapress.com/article/doi/10.48130/mpb...
#Alkaloids #MedicinalPlants

New Polyketides and a Ferroptosis Inhibitor from the Marine-Derived Fungus Diaporthe searlei CS-HF-1

#Fungus
#Diaporthe
#alkaloids
#polyketides
#ferroptosis

www.mdpi.com/1660-3397/23...

New Metal‑Organic Framework Enables Precise Alkaloid Structure Study

Tokyo researchers unveiled APF‑80, a metal‑organic framework that solved crystal structures of twelve nucleophilic compounds—including caffeine, nicotine and abacavir—using the sponge method. getnews.me/new-metal-organic-framew... #apf80 #alkaloids

Satya Swathi Nadakuduti follows in the #SOLRUB2025 meeting presenting about a #Rubicaceae species, Mitragyna speciosa, capable of produce #alkaloids with potential pharmaceutical applications.

Bypassing the abnormal Chichibabin reaction dead-end provides a biomimetic access to pre-haouamine Haouamines are highly constrained marine alkaloids possessing a unique in nature skeleton. The high degree of complexity of such alkaloids raises questions about their chemical assembly. This is addre...

Bypassing the abnormal Chichibabin reaction dead-end provides a biomimetic access to pre-haouamine by Mehdi A. Beniddir et al. 🔹 Biomimetic strategy avoids Chichibabin dead-end, enabling concise synthesis of pre-haouamine. 🌊
doi.org/10.1039/D5QO...
#OrganicSynthesis #BiomimeticChemistry #Alkaloids

✨ From Graphical Reviews Collection
#Chemical transformations of indole #alkaloids provide rapid access to novel scaffolds for #DrugDiscovery. Ring distortion strategies re-engineer natural products into diverse bioactive compounds.

🔍 Read now: www.thieme-connect.com/products/ejo...
#ChemSky

This review highlights the mechanisms of action of several key alkaloids in heart failure, arrhythmia, hypertension, myocardial infarction, and fibrosis.
#IJDDP #alkaloids #Cardiovascular #arrhythmia #hypertension
www.sciltp.com/journals/ijd...

🍃 Enter #Phytocompounds! We dove into PubMed, EMBASE & Cochrane, screening 13 clinical trials per #PRISMA 📚⚖️From #Flavonoids like #Quercetin & #Luteolin to #Alkaloids (#Caffeine, #Huperzine A) & #Terpenoids (#Ginkgolides)🌿🔬 @mdpiopenaccess.bsky.social #Neuroscience
👉 www.mdpi.com/2218-1989/15...

Exploration of plant alkaloids as potential inhibitors of HIV–CD4 binding: Insight into comprehensive in silico approaches This study investigates the potential of alkaloids – nitidine, harmine, harmaline, berberine, and magnoflurine – as inhibitors of HIV –CD4 binding, focusing on their molecular interactions, binding…

In silico docking and simulations reveal #alkaloids (nitidine, berberine, magnoflurine) show strong #CD4 binding, stability and good #pharmacokinetics, highlighting their potential as novel anti-HIV inhibitors. #HIV

#OpenAccess in Open Chemistry:

Unlocking complex spirocyclic oroidin #alkaloids like palau’amine🔬 Carl Lovely & co-workers report a novel Diels–Alder sequence with tandem #TBAF desilylation, oxidation & rearrangement to create a versatile intermediate for #TotalSynthesis.
#cycloaddition

👉 buff.ly/mi6k9Sl

Flower bud of Datura, creamy yellow

Open trumpet flower in white

Angels trumpet, Datura inoxia, yellow before white, for this one-night #flower... A native to the southwestern USA, this toxic plant has tropane #alkaloids, famous in the #nightshade family

In the journal Horticulture Research, by integrating Illumina, PacBio HiFi, and Hi-C technologies, the scientists assembled 88 pseudochromosomes representing the 90 actual chromosomes of this medicinal plant.
#Whole-genome duplication #Alkaloids
Details: doi.org/10.1093/hr/u...

👁️ Some plant foods fight back — with alkaloids that may harm your eyes, nerves, and gut.

Found in: 🍅 tomatoes, 🍆 eggplant, ☕ coffee, 🍫 chocolate, 🫘 soy, 🍊 citrus, 🌿 spices.

🎥 The truth you haven’t been told:
👉 youtu.be/VTRRJnM10D4

#Alkaloids #PlantToxins #EyeHealth #Carnivore #LowCarb

Sharma et al. covered recent advances in the design of #yeast cell factories for the synthesis of #terpenoids, #alkaloids, #phenylpropanoids, and other #natural chemicals, primarily focusing on #Pichia species
sciencedirect.com/science/arti...

🧠🍇Can #Plants fight #BrainAging? New #Review shows #Polyphenols, #Alkaloids & #Terpenoids vs #Neurodegeneration 👊🛡️Nature’s real brain-hacking kit—backed by #Neuroscience🧪✨ @mdpiopenaccess.bsky.social #Longevity #BrainHealth www.mdpi.com/2218-1989/15...

Original post on mastodon.social

3-Jun-2025
Two plant species invent the same chemically complex and medically interesting substance
The elucidation of the biosynthetic pathway of #ipecacuanha #alkaloids shows how two distantly related plant species could develop the same substance independently […]

🧠🍇Can #Plants fight #BrainAging? New #Review shows #Polyphenols, #Alkaloids & #Terpenoids vs #Neurodegeneration 👊🛡️Nature’s real brain-hacking kit—backed by #Neuroscience🧪✨ @mdpiopenaccess.bsky.social Metabolites #Longevity #BrainHealth www.mdpi.com/2218-1989/15...

🧠🍇Can #Plants fight #BrainAging? New #Review shows #Polyphenols, #Alkaloids & #Terpenoids vs #Neurodegeneration 👊🛡️Nature’s real brain-hacking kit—backed by #Neuroscience🧪✨ @mdpiopenaccess.bsky.social Metabolites #Longevity #BrainHealth www.mdpi.com/2218-1989/15...

Deep purple colored five petaled flower of blue cohosh, with yellow, anthers and a green stigma

Blue cohosh, Caulophyllum thalictroides in the Beberidaceae, starts devilishly purple, turns green ... Now flowering in Ithaca... Full of medicinal and poisonous #alkaloids and #saponins. Bluish fruits are not dispersed by ants

#WildflowerHour
#bloomscrolling
#botany
#NativePlants

#Batzelladine: A treasure trove of biological activity 🌊 These #alkaloids exhibit anticancer, antiviral, & antibacterial properties. Jamie Breunig and Joshua Pierce highlight key disconnections used to build these marine natural products

👉 buff.ly/9oNHywN

🧠🍇Can #Plants help us outsmart #Neurodegeneration? A new #Review dives into how #Polyphenols, #Alkaloids & #Terpenoids fight #Brain #Aging 👊✨ Think of it as nature’s biohacking toolkit—backed by #Neuroscience🧪🛡️@mdpiopenaccess.bsky.social Metabolites
🔬 Read for free: www.mdpi.com/2218-1989/15...

Total synthesis of anti-addictive alkaloid in just seven steps A streamlined synthesis of the psychoactive compound ibogaine could open up new opportunities in the treatment of drug addiction and depression

Total synthesis of anti-addictive alkaloid in just seven steps #Science #Chemistry #OrganicChemistry #TotalSynthesis #Alkaloids

Leaf-dwelling fungi enhance black poplar chemical defenses and mediate multi-trophic insect interactions In a new study published in Ecology Letters, researchers from the Max Planck Institute for Chemical Ecology and the University of Kiel, Germany, report on the influence of an endophytic fungus of the ...

#Leaf-dwelling #fungi enhance black #poplar chemical defenses and mediate multi-trophic #insect interactions.

#Cladosporium #predation #herbivore #alkaloids #stachydrine #metabolomics #microbiome

phys.org/news/2025-02...

PhD on LSD? Vivian Kathambi is making good progress on the extraction of #ergot #alkaloids from #seeds of East African #Ipomoea, at Kew's Phytochemistry Lab - mentored by Dr Moses Langat.

A collaboration between Ghent University, Kew & EA Herbarium.
@ugent-botany.bsky.social
@rbgkew.bsky.social

Development of Quantitative Structure–Anti-Inflammatory Relationships of Alkaloids Alkaloids are naturally occurring metabolites with a wide variety of pharmacological activities and applications in science, particularly in medicinal chemistry as anti-inflammatory drugs. Because the...

Alvascience tools have been used in "Development of Quantitative Structure–Anti-Inflammatory Relationships of Alkaloids" doi.org/10.3390/ecso...

Check Alvascience tools at: www.alvascience.com/alvadesc/

#moleculardescriptors #qsar #machinelearning #cheminformatics #alkaloids

It’s called 7 hydroxy , In #kratom there are many #alkaloids that contribute to the opioid and stimulant like effects. Mostly Mitragynine and 7hydroxy-mitragynine but in the plant form you ingest very little of it. Mit concentrations see 2% while 7 hydroxy is .002%. 7 is suspected to behind

New Insights into Chemical Profiles and Health-Promoting Effects of Edible Mushroom Dictyophora indusiate (Vent ex. Pers.) Fischer: A Review Mushrooms are valued for their culinary and medicinal benefits, containing bioactive compounds like polysaccharides, terpenoids, phenolics, lectins, and ergosterols. This review aims to encourage rese...

New Insights into Chemical Profiles and Health-Promoting Effects of Edible Mushroom Dictyophora indusiata (Vent ex. Pers.) Fischer: A Review

#mycosky
#fungifriends
#Dictyophoraindusiata
#Phallusndusiatus
#mushrooms
#monoterpene
#alkaloids
#sesquiterpenes

www.mdpi.com/2309-608X/11...