#Albumin or #Keratin Casts Obstruct Renal Tubular and Vascular Lumens Following Kidney #Ischemia

#VisualAbtract by Akshaya Jayachandran

www.kireports.org/article/S2468-0249(26)02...

Understanding the physiology behind symptoms matters.

Myth: Chest pain without blockages = non-cardiac.
Fact: CMD can cause real ischemic symptoms, affecting quality of life and risk.

#CMD #Ischemia #HeartHealth #PatientCenteredCare #Cardiology

Lactate increases oxygen unloading of preconditioned blood from male elite breath‐hold divers Physical performance can be improved in aerobic athletes and breath-hold divers (BHD) by limb exposure to repetitive ischemia: remote ischemic conditioning (RIC). RIC protects against cardiac ischemi...

Evidence that #erythrocyte and #cardiac lactate dehydrogenase a is higher in breath-holding #divers (BHD) compared to matched controls, and that #lactate facilitates #oxygen-unloading in blood from BHD after remote #ischemia conditioning, similar to diving mammals.
doi.org/10.14814/phy...

AI-QCTISCHEMIA uses #AI + #CCTA to predict #ischemia —✅ outperforming conventional non-invasive tests & validated across sex & age groups. A step forward for non-invasive #CAD assessment.

▶️www.jscai.org/article/S2772-9303(25)01...

#CardioSky

Impact of peroxisomal biogenesis protein PEX11a deficiency on cardiomyocyte structure and cardiac function in a mouse model. #cardiomyocyte #peroxisome #ischemia #oxidativestress #lipidmetabolism #MALDIMSI
www.mdpi.com/2073-4409/15...

Mitochondrial protection role of oxidoreductase-like domain containing 1 in myocardial cells under hypoxia
#OpenAccess in #MedicalGasResearch: doi.org/10.4103/mgr....
#mitochondria #cardiology #hypoxia #OXLDI #cardiovascular #ischemia #metabolism #cellbiology

‘The monthly curse’: menstrual-associated coronary artery vasospasm in a premenopausal woman—a case report AbstractBackground. Catamenial coronary vasospasm has recently been recognized as a refractory form of vasospastic angina, characterized by recurrent episo

‘The monthly curse’:
‘De maandelijkse vloek’:

menstrual-associated coronary artery vasospasm in a #premenopausal woman— a case report

#catamenial #coronary #vasospasm🫀
#perimenopause #HRT #estrogen
#refractory #angina #ischemia

#ANOCA #INOCA #MINOCA 🫀
#NOCAD

academic.oup.com/ehjcr/articl...

Epithelial membrane protein 1 drives hepatic stellate cell activation via the TLN1/FAK cascade in MASLD donor liver transplantation - Molecular Biomedicine The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has significantly increased, prompting the increased use of steatotic donor livers in transplantation, contributing t...

#Research
Epithelial membrane protein 1 drives hepatic stellate cell activation via the TLN1/FAK cascade in #MASLD donor liver transplantation doi.org/10.1186/s435...

#Ischemia #reperfusion #injury #LiverTransplantation #HepaticStellateCell #EpithelialMembraneProtein1

#CarbonMonoxide has #antiischemic and #antiinflammatory effects. This study explores the potential of #CORMA1, a molecule that effects controlled CO release, to protect #kidneys from warm #ischemia and #reperfusion injury in rat and swine models.
doi.org/10.14814/phy...

#Nicotinamide #N-methyltransferase inhibition is shown to improve limb function in experimental #peripheral #artery disease in male mice.
doi.org/10.14814/phy...
#Ischemia #SkeletalMuscle

This review highlights how #ferroptosis defence relies on #NADPH-driven redox recycling, explores its links to metabolic dysregulation in #neurodegeneration and #ischemia, and highlights emerging anti-ferroptosis therapies. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

Honored that @ShockSociety approved my reappointment as the Editor-in-Chief for @ShockJournal and excited to lead the journal for the next five years. We publish high quality papers in #sepsis #trauma #ischemia #inflammation

"Pernio-like lesions ( #COVID19 toes) and associated #limb #ischemia are also diagnosed in COVID-19." #amputation

@PVaughanShaw @JJEarnshaw @juliomayol @ksoreide #vascularsurgery #vascular #Ischemia @vascularsurgery @VascularSVS @FutureVascSurgn @SVM_tweets @bjsacademy.bsky.social @martyn-evans.bsky.social @drjuliomayol.bsky.social @bjsopen.bsky.social @gio-marchegiani.bsky.social @malinasund.bsky.social

Dr. Igor Samatoshenkov from Universitätsklinikum Brandenburg an der Havel (Brandenburg, Germany) explains how to break the wall of incurable limb #ischemia with #gene #therapy by creating new collateral circulation and regenerating tissues.
#FallingWallsLab #FallingWalls

Using a novel remote occlusion real-time method to image acute #ischemia, this comparison of #Manganese-enhanced & late #gadolinium enhancement #MRI assesses #myocardium damage in a murine ischemia–reperfusion model & reports that LGE MRI may overestimate infarct size

Critical Limb Ischemia Outcomes Worse Among Those With MPNs | ASH Clinical News | American Society of Hematology

Among patients hospitalized for critical limb #ischemia, individuals with #MyeloproliferativeNeoplasms #MPNsm had an increased risk of major adverse #cardiovascular and limb events, especially those with #EssentialThrombocythemia and #myelofibrosis: ow.ly/gvec50WjPan
#HemeSky #HemeOnc

Research on effects of electric pedestal #fan use during daylong exposure of older adults to simulated indoor #overheating reports lack of definite effects on systemic markers of #enterocyte damage, #inflammation or #renal #ischemia.
doi.org/10.14814/phy...
#HeatStress

🚨 #April #2025 edition of #Genes & #Immunity is now online: www.nature.com/gene/volumes... @springernature.com

🧐 Read all about: #humoral #immunity #lipidomics #metabolism #allergy #ischemia #stroke #pancreatitis #multiomics #cancer #immunology #immunotherapy #vaccines #diabetes

Check out our latest issue in @theinnovation.bsky.social!!!
Volume 6, Issue 4 is now online!
www.cell.com/the-innovati...
#research #Robot #climate #3DPrinting #artificalintelligence #Medicine #Health #Neuroscience #Chemistry #ischemia #aging #oculardisease #Cancer #Physics #astrology

Guideline-Directed Medical Therapy #GDMT & Outcomes in #ISCHEMIA Trial

#CardioSky #JACC

www.jacc.org/doi/10.1016/...
@michaeldshapiro.bsky.social @jaccjournals.bsky.social @vietheartpa.bsky.social @erinmichos.bsky.social @load-dependent.bsky.social @drmonalidesai.bsky.social @rblument1.bsky.social

La Méridienne - Transplantation et médecine narrative - Radio Campus Tours - 99.5 FM Image by Silke from Pixabay Émission en partenariat avec l’INSERM Grand-Ouest Nous commettons aujourd’hui une nouvelle émission en partenariat avec l’ Inserm Grand Ouest !Au programme, cinq invités po...

Nouvelle émission en partenariat avec Radio Campus Tours !
Au programme : transplantation rénale et médecine narrative.
Avec le laboratoire Inserm / Université de Tours #Ischemia et le CHU de Tours #FHUSuport
www.radiocampustours.com/emissions/la...

#SoMe4Surgery #MedTwitter #SurgEd #Surgery #MedicalTechniques @bjsacademy.bsky.social @bjsopen.bsky.social #vascularsurgery #vascular #Ischemia

Case 173: Microvascular Dysfunction in Hypertrophic Cardiomyopathy

63-yrs old with ASH with chest pain

Video discussion of the case and the use of adenosine stress perfusion CMR to diagnose
www.mricardiac.com/case173/

#cmrsimplified #cmr #cardiacmri #whyCMR #stressCMR #HCM #ischemia

Severe ischemia-reperfusion injury induces epigenetic inactivation of LHX1 in kidney progenitor cells after kidney transplantation Severe ischemia-reperfusion injury (IRI) causes acute and chronic kidney allograft damage. As therapeutic interventions to reduce damage are limited yet, research on how to promote kidney repair has g...

Severe ischemia-reperfusion injury induces epigenetic inactivation of LHX1 in kidney progenitor cells after kidney transplantation.👩‍🔬🥼👨‍🔬🧪 #KidneyDisease #Transplant #NephSeq #Epigenetics #Ischemia

👇👇

www.amjtransplant.org/article/S160...

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair Researchers have discovered that DNA methylation is crucial for reprogramming astrocytes into stem cells in the adult mouse brain, especially after ischemic injury, with potential implications for reg...

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair 🧠🧬🔬 www.news-medical.net/news/2024090... #DNAmethylation #Astrocytes #StemCells #Neurogenesis #Epigenetics #Neuroscience #Ischemia

A role for astrocytic Insulin-like Growth Factor I receptors in the response to ischemic insult
doi.org/10.1177/0271...
#astrocytes #ischemia #neuroglia