#mostdownloaded
Understanding the health impacts of the climate crisis 🌍
This article by Prof Mark Maslin and colleagues from March 2025 is proving popular - find out why ⏬
www.sciencedirect.co...
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#MostDownloaded
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Our #mostdownloaded article over the past 90 days is this 2024 review by Chew & Kamangar 👏🏼
Approach to pancytopenia: From blood tests to the bedside
Read on to update your knowledge ⤵️
www.sciencedirect.com/science/article/pii/S147...
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#mostdownloaded
Approach to pancytopenia: From blood tests to the bedside
This review from 2024 is proving popular with readers! Want to find out more to improve your practice? 👀⏬
www.sciencedirect.com/science/article/pii/S147...
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Scientists identify GDF10, a BMPs/BMPRs family #biomarker, as a potential diagnostic marker for #LungSquamousCellCarcinoma (LUSC) and a regulator of the tumor immune microenvironment, offering insights for effective LUSC treatment. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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#Electroacupuncture-induced activation of #serotonergic neurons in the dorsal raphe nucleus alleviates #CognitiveDysfunction in APP/PS1 mice, by activating #glutamatergic neurons and enhancing #SynapticPlasticity. #AlzheimersDisease #medsky
#MostDownloaded: link.springer.com/article/10.1...
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Porphyromonas gingivalis Induces Chronic Kidney Disease through Crosstalk between the NF-κB/NLRP3 Pathway and Ferroptosis in GMCs
This study demonstrates that P. gingivalis induces #ChronicKidneyDisease (CKD) in mice by triggering crosstalk between the NF κB/NLRP3 pathway and #ferroptosis in GMCs, establishing the importance of periodontitis therapy in CKD management. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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TOPK is overexpressed in moderately to poorly differentiated #ColorectalCancer, while its inhibition enhances the sensitivity of CRC cells to #Radiotherapy by suppressing the downstream pathways of #DNADamageResponse. #medsky
Read our #MostDownloaded article: link.springer.com/article/10.1...
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TOPK is overexpressed in moderately to poorly differentiated #ColorectalCancer, while its inhibition enhances the sensitivity of CRC cells to #Radiotherapy by suppressing the downstream pathways of #DNADamageResponse. #medsky
Read our #MostDownloaded article: link.springer.com/article/10.1...
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Research Progress on the Pathogenesis and Treatment of Neoatherosclerosis
This review summarizes the influencing factors, pathological characteristics and pathogenesis of #Neoatherosclerosis, highlighting current challenges, and provides a theoretical basis for the development of new #stents in the future. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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High Hydrostatic Pressure Exacerbates Bladder Fibrosis through Activating Piezo1
This study reveals that #Highhydrostaticpressure may exacerbate #BladderFibrosis through the activation of #Piezo1, which may serve as a potential therapeutic target for mitigating bladder fibrosis associated with #BladderOutletObstruction. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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TRPC6 knockdown alleviates #RenalFibrosis by reducing the expression of #fibrotic markers and mitigating #apoptosis and #inflammation of primary tubular epithelial cells (PTECs) via downregulating the PI3K/AKT/GSK3β pathway. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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This study reveals that elevated #serumferritin levels are associated with a higher prevalence of #MAFLD and advanced #liverfibrosis and their combination with #diabetes significantly increases the risk of liver fibrosis. #NHANES #MostDownloaded #medsky
Read: link.springer.com/article/10.1...
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#ArtificialIntelligence-powered #WearableEEG neurofeedback improves language, social interaction, and problem behaviours, highlighting its potential to target core brain mechanisms underlying #AutismSpectrumDisorder (ASD) symptoms. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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A review on how #ArtificialIntelligence helps in #MedicalMetaverse construction and its applications in diagnosis, education, and consulting, with inputs on the current challenges & future prospects. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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This study reveals that #SLC9A2 acts as a #TumorSuppressor through the #MAPKpathway and may be a potential target for #ColorectalCancer (CRC) diagnosis, prognosis and #therapy. #bioinformaticanalysis #biomarkers #MostDownloaded #medsky
Read: link.springer.com/article/10.1...
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This study used #MendelianRandomization analysis to demonstrate a bidirectional causal relationship between the #GutMicrobiota and #Infertility, and identify different genera associated with male/female #Infertility and related diseases. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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This review explores the biology of #exosomes, the role of adipose tissue-derived exosomes (AT Exos) in various #MetabolicDisorders, and their potential clinical application as #biomarkers and #TherapeuticTargets. @2024HUST
#MostDownloaded: link.springer.com/article/10.1...
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This case study describes a successful #orthodontic treatment of a #juvenilepatient with #bimaxillaryprotrusion and #mandibularRetrusion, using a bracket-free invisible orthodontic technique. #ClearAligners #medsky
#MostDownloaded: link.springer.com/article/10.1...
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An overview of the pathophysiology of #CysticFibrosis (CF), application of #StemCellTherapy and #GeneTherapy in CF, their types & mechanisms of action, along with the challenges & future directions in the field. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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TREM2-mediated Macrophage Glycolysis Promotes Skin Wound Angiogenesis via the Akt/mTOR/HIF-1α Signaling Axis
TREM2 promotes #angiogenesis during #WoundHealing by enhancing #glycolysis and #lactylation in #macrophages in wounded tissues via activating the Akt/mTOR/HIF-1α signaling pathway. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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This study shows that LATS1-regulated YAP1 phosphorylation and subcellular localization drives B-ALL #tumorigenesis, highlighting the #oncogenic role of YAP1 and its potential as a novel diagnostic and #TherapeuticTarget. #medsky
#MostDownloaded: link.springer.com/article/10.1...
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Understanding the health impacts of the climate crisis 🌍
This discussion by Maslin et al is the #mostdownloaded paper from our March issue! 👏🏼
www.sciencedirect.co...
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This review evaluates the applications, strengths, & limitations of #NutritionalAssessment tools for #cancer patients, helping clinicians select the most appropriate tool for effective nutritional management. #PGSGA #GLIM. #medsky
#MostDownloaded link.springer.com/article/10.1...
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A review of the mechanisms underlying copper homeostasis and #Cuproptosis in the nervous system and #NeurodegenerativeDiseases, with fresh insights into cuproptosis-based #TargetedTreatment of neurodegenerative diseases. #medsky
#MostDownloaded #OpenAccess: link.springer.com/article/10.1...
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»#Temu is the #mostdownloaded app on the US App Store in 2024: The shopping app moved into the No. 1 slot last year, stealing the position from #TikTok, which held the title in in 2022.« https://techcrunch.c
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