Congrats @juliaplank.bsky.social on this fascinating research.
A presentation from Dr. Plank at the RASopathies Symposium last summer describes this work. #neurosky #medsky #neuroscience #myelin #mri
youtu.be/9MQ7FN1e-b0?...

Quantitative Multicomponent T2 Myelin-Water Fraction Mapping Package • Center for Advanced Imaging Innovation and Research Quantitative mapping of myelin content using multi-T2-component fitting of multi-echo spin-echo MRI data.

🚨 New resource alert! Software for turning standard multi-echo spin-echo #MRI data into quantitative maps of #myelin content in white matter.

Particularly suitable for studies involving MRI data acquired across multiple imaging sessions or scanners.

📦 cai2r.net/resources/qu...

🧪

UK Glia 2026 UK Glia 2026 meeting will highlight the pivotal role of glia in brain physiology, offering invaluable insights for those investigating glia function in both health and disease. Find out more about the...

Late breaking abstracts- posters only!

Don't miss the opportunity to see the mighty Bal Khakh FRS
He is entertaining, British and returning to the UK to bring his brilliance to the @ukdri.ac.uk

#neuroscience #glia #astroctyes #microglia #oligodendrocytes #myelin

www.physoc.org/events/uk-gl...

Two mechanisms, two regional outcomes. Every BCI degrades because the biology fails. Industry can't fund the basic science to understand why. That's what NIH and NSF are for. Industry builds airplanes. Federally funded research builds the runway. #NeuralEngineering #BCI #Myelin

#AIGS26 | Day 1 (Sept 16) 🧠

Session 2: "New Insights on Glial Cells in Neurodegeneration: A Focus on Metabolism".

Speakers:
🔬 Alberto Pascual @ibis-investigacion.bsky.social #microglia #metabolism
🔬 Maite Solas @unav.edu #astrocytes #alzheimers
🔬 Vanja @tepavcevicvanja.bsky.social #myelin #MS

Psychedelics Remodel Myelin to Heal PTSD - Neuroscience News New research reveals that psilocybin and MDMA promote long-term PTSD recovery by physically remodeling myelin insulation in the brain, synchronizing disrupted neural circuits.

#Psychedelics Remodel #Myelin to Heal #PTSD
#Neuroscience #Psychology

Oligodendrocyte-specific Fus depletion preserves CA1 single-unit fidelity and stabilizes network dynamics during chronic recording Oligodendrocyte-specific Fus depletion preserves CA1 single-unit fidelity and stabilizes network dynamics during chronic recording, Wellman, Steven M, Guzman, Kelly, Suematsu, Naofumi, Thai, Teresa, T...

📄 Wellman, Guzman, Suematsu et al. (2026). Oligodendrocyte-Specific Fus Depletion Preserves CA1 Single-Unit Fidelity and Stabilizes Network Dynamics During Chronic Recording. Journal of Neural Engineering. doi.org/10.1088/1741...

#NeuralEngineering #BCI #Neuroscience #UPitt #Myelin

A big thank you to Fondazione Telethon for their continued commitment to research and for supporting projects aimed at making a real difference for people living with rare genetic diseases.

#raredisease #research #Telethon
#oligodendrocyte #myelin

CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity CDC42-effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin-dependent scaffolding of myelin. Myelin o...

If you're interested in the factors that enable the regular structure of CNS #myelin sheaths by #oligodendrocytes, check this out. Featuring a #CDC42 - effector proteins - #septin axis. Congrats to 1st author Sophie, and a big thank you to all who contributed

onlinelibrary.wiley.com/doi/10.1002/...

We found that enhancing neuronal activity via #tDCS coupled with low-intensity physical activity accelerates #remyelination and increases #oligodendroglia survival and maturation in a model of #myelin damage in the mouse motor cortex

More Hope for Re-myelination Therapy An effective re-myelination drug is one of the holy grails of treatment for MS. That would mean less damage, and potential reversibility of some of the ongoing damage, before neurons have become be…

msmartinecom.wordpress.com/2025/12/18/m...

#MultipleSclerosis #Remyelination #myelin #blog #disability #neurology

Study implicates enzyme in neurodegenerative conditions OHSU research finds a specific enzyme is involved in myelin breakdown that causes conditions such as MS, stroke, Alzheimer's.

Dr. Larry Sherman, professor at OHSU’s Oregon National Primate Research Center, led research identifying the enzyme CEMIP as a key player in #myelin breakdown linked to conditions like #AlzheimersDisease. news.ohsu.edu/2025/12/11/study-implica...

Losing Myelin Scrambles the Brain’s Sensory Signals - Neuroscience News New research reveals that even a small loss of myelin—the protective coating around neurons—can severely disrupt how the brain sends and interprets sensory information.

Losing #Myelin Scrambles the Brain’s Sensory Signals
#Neuroscience

Aerobic exercise may promote myelin repair Aerobic exercise may promote myelin repair Published: Aerobic exercise may help the brain repair myelin in some areas for people with multiple sclerosis, according to early pilot data presented at the 41st ECTRIMS Congress in Barcelona. The single-blind...

Aerobic #exercise may help the #brain repair #myelin in some areas for people with #MultipleSclerosis: ms-uk.org/news/aerobic-exercise-ma...

Newborn Risks: Do you really need the hepatitis B vaccine? The Truth Behind the Policy. In today's episode we're examining the forgotten controversy surrounding the hepatitis B vaccine. Given to every newborn despite less than one in a million children benefiting, the universal policy is set for re-evaluation. We delve into the history of safety concerns, including links to autoimmune disorders and demyelinating events, which evidence shows indeed occur. We discuss Congressional hearings that highlighted serious side effects, including infant death, seizures, and autism, noting that risks vastly outweighed benefits for newborns. Finally, we explore the potential non-medical justifications for universal vaccination, such as increasing sales or capturing a "captive audience".  Learn what is at stake as the policy is finally assessed, as detailed in the source material titled Why is Every Newborn Forced to Get A Hepatitis B Vaccine? → https://www.midwesterndoctor.com/p/why-is-every-newborn-forced-to-get-369

📣 New Podcast! "Newborn Risks: Do you really need the hepatitis B vaccine? The Truth Behind the Policy." on @Spreaker #acip #autism #autoimmunity #b #chronic #controversy #demyelinating #efficacy #healthcare #hepatitis #infants #myelin #neurological #newborns #policy #risks #safety #seizures

Brilliant PhD defense today by Carla Peiró on myelin as an energy supplier! 🔬⚡️@upv/ehu uncovering how #myelin fuels #oligodendroglia. Outstanding work and its contribution to understanding #brain #energy #metabolism @matutelab.bsky.social @iisbiobizkaia @labdomercq @achucarro.bsky.social @ciberned

It's Friday and we have a new PhD!!
Congratulations Dr. Peiro-Moreno, Zorionak Carla!! 👏
"Biological effects of #myelin internalization on the #oligodendroglial lineage"

Aging and diet alter the protein ubiquitylation landscape in the mouse brain - Nature Communications Post-translational modifications (PTMs) regulate protein homeostasis and function. Here, the authors applied mass spectrometry to uncover extensive changes in protein ubiquitylation in the aging mouse...

www.nature.com/articles/s41... Very interesting study by Antonio Marino and colleagues examining how protein post translational modifications change during #aging and diet modification. Intriguing to see #myelin proteins showing up prominently.

This review explores #antigen-specific #immunotherapy as a targeted strategy to restore #myelin tolerance in #MultipleSclerosis, outlining disease mechanisms, current treatments, and challenges in transformative therapies. @uab.cat

#OpenAccess #STTT: doi.org/10.1038/s413...

Serum proteomics in people with pre-symptomatic #MultipleSclerosis reveals #myelin damage up to 7 years before symptoms—preceding axonal injury by ~1yr. #Astrocyte involvement emerges only at clinical onset. #MS
www.nature.com/articles/s41...

#neurology #publichealth #SDGs #pediatrics #ecology #health #myelin

Exposure to higher levels of
fine particulate air pollution
during pregnancy
is linked to slower myelination,
an indicator of brain maturation,
in newborns within their first month of life.
.
www.sciencedirect.com/science/arti...

Vollum Seminar Series continues Thursday (10/16) with Dr Cody Call presenting "Unraveling how #oligodendrocytes
generate and pattern #myelin" at noon in M1441 of the Vollum. Login & stream from link on site: bit.ly/4dXx9pc #OHSUResearch #OHSU #neuroscience

Thank you for posting this! @gregory-ms.com didn't catch It in the MS search queries, but I just added it to the correct subject. It will be included in next week's newsletter. 🙇

#MSchat #MultipleSclerosis #Myelin

If you’re interested in #neurodevelopmental disorders, or the transcriptional network regulating #myelin, or both, check this out. Congratulations Gilad and @barakboaz.bsky.social. I’m happy that we were able to contribute a tiny bit!

Search Gregory's Database

Just found out about #Baicalein. There is a lot of research coming from traditional Chinese medicine with hope for people with #MultipleSclerosis

gregory-ms.com/search/?type...

#mschat #neurosky #neurology #myelin

Many thanks to Gilad Levy who led the entire study and the amazing team who made this possible: Asaf Marco, Inna Slutsky, Elior Peles, @myelincentric.bsky.social Hauke Werner, Yaniv Assaf, Noam Shomron

#myelin, #oligodendrocytes, #whitematter, #multiplesclerosis, #gtf2i

Marathon Running Triggers Temporary Myelin Changes, Study Finds

A study of ten experienced runners (ages 45‑73) found marathon completion cut myelin water fraction by up to 28% in pontine crossing tracts, with levels returning to baseline by two months. getnews.me/marathon-running-trigger... #marathon #myelin

Magnetically controlled drug-loaded coaxial electrospun suspension fibers for promoting Schwann cell myelination - PubMed Myelination of Schwann cells is essential for peripheral nerve regeneration, yet existing in vitro models struggle to accurately recapitulate the in vivo myelination process. In this study, a novel th...

This is so cool. Magnets!!

pubmed.ncbi.nlm.nih.gov/40934538/

#MSchat #neurology #multiplesclerosis #myelin

Human myelinated brain organoids with integrated microglia as a model for myelin repair and remyelinating therapies Human myelinated brain organoids with integrated microglia can be used to investigate demyelination, remyelination, and remyelinating therapies.

Human myelinated brain organoids with integrated #microglia as a model for #myelin repair and remyelinating therapies | Science Translational Medicine
www.science.org/doi/10.1126/...

Unfortunately, things go downhill from there. Myelin starts to degenerate towards later adulthood. That works on the last-in, first-out principle, with the prefrontal cortex being the first zone to go. 3/3

#neuroskyence #myelin