#Renal focal global #glomerulosclerosis relates to #aging and #hypertension and begins with tuft contraction of #glomeruli. This report shows associated #biomarkers of #podocyte depletion, cell #senescence, and activation of #parietal #epithelia #cells.
doi.org/10.14814/phy...
#Kidney #Physiology
"Calcium Shock Enables Efficient and Programmable Particle Delivery for Genome Editing Applications," presented by Nicole Vo, PhD
@uwmedicine.bsky.social #organoids #genome #renal #podocyte #cells #nephsky #research
Watch: youtu.be/YeAmH_kN2o8
Safranal Ameliorates Renal Damage, Inflammation, and Podocyte Injury in Membranous Nep
#Safranal protects against membranous #glomerulonephritis in rats by reducing #proteinuria, #inflammation, and #podocyte injury; restoring #nephrin/podocin levels; and suppressing NF-κB-driven renal inflammation via Sirt1 pathway activation.
#OpenAccess: doi.org/10.1007/s115...
#Podocytopathies are kidney diseases characterized by protein loss in the urine owing to #podocyte injury or dysfunction - more in our PrimeView. https://www.nature.c
Urinary #Podocyte Loss is Associated With #Treatment Response in Patients With Primary #NephroticSyndrome
#VisualAbstract by Dr Pallavi Prasad, MD, DNB ( Nephrology)
www.kireports.org/article/S2468-0249(25)00...
A Figure showing the causes of aetiology-defined podocytopathy types.
Distinct mechanisms of #podocyte damage underlie the six major aetiological categories of #podocytopathies, comprising autoimmune, genetic, adaptive, toxic, infectious or monoclonal causes.
https://www.nature.c
A Figure showing the main histological glomerular lesion patterns and how they relate to aetiology-defined podocytopathy types.
#Podocyte injury can result in five distinct glomerular lesion patterns, of which each can have different causes, varying severity and capacity to be repaired.
https://www.nature.c
📰New & Featured | #Cell: Kidney podocytes shed autoantibody-triggered EVs (#AIT-EVs) to remove immune complexes whilst this also drives #podocyte injury.
Urinary AIT-EVs serve as a non-invasive #biomarker of active membranous #nephropathy
#MembranousNephropathy #KidneyDisease
Thanks to #BioScience_Forum speaker Harold Bernstein Pres of R&D & CMO of #MazeTx for sharing about #MZE829 and #MZE782 therapies for #ChronicKidneyDisease & #PKU & for inspiring me to build case studies about APOL1-mediated #CKD & PKU for my next #Genetics class!! Btw- I want a #podocyte plushie…
#TRPC6 channels are implicated in pathogenesis of severe #nephrotic syndromes. This study of TRPC6 in normal physiological #podocyte functions reports roles in #MMP7-shedding of #nephrin ectodomains and #apoptosis.
doi.org/10.14814/phy...
#Renal #IonChannels
The Two Levels of Podocyte Dysfunctions Induced by Apolipoprotein L1 Risk Variants
#OpenAccess
Full text 👉 buff.ly/eNYwDuQ
#APOL1
#nephropathy
#podocyte
#dysfunction
#apoptosis
#Nephrology
#KidneyCare
#nephsky
#medsky
#RenalPath
The Two Levels of Podocyte Dysfunctions Induced by Apolipoprotein L1 Risk Variants
#OpenAccess
Full text 👉 buff.ly/eNYwDuQ
#APOL1
#nephropathy
#podocyte
#dysfunction
#apoptosis
#Nephrology
#KidneyCare
#nephsky
#medsky
#RenalPath
Wooden Podocyte Magnet on a grey set of metal drawers
Of course, magnets are not just for fridges! They also look great on office drawers -
This one is the #Podocyte Magnet and if you back my campaign in the next 8 hrs, you'll be able to bag one of these absolutely free!
#sciart #artsky #art #medsky #scicomm #nephsky #kidney #nephrology
Wooden podocyte kidney cell magnet - might also look like an octopus
If you back the project in the first 48 hrs, you will receive a super special wooden #podocyte magnet. Now, these are absolutely limited to 20, and when they're gone, they're gone!
#sciart #scicomm #painting #art #bioart #artsky #nephsky #medsky
Commentary
The podocyte gets a pedicure: tiny nail clippers for podocyte foot processes
L. Al-Rabadi and L. Beck
doi.org/10.1016/j.kint.2025.05.009
Original article: doi.org/10.1016/j.kint.2025.04.010
#NephSky #MedSky #podocyte
Cells expressing Yap (stained green). Left side without condensate induction, right side two minutes after condensate induction, now filled with green dots.
Please share …. 🙏
📣 Very soon, we’ll have an open PhD position starting in fall 2025 — this time not on cilia, but on YAP & TAZ in podocytes and their regulation via LLPS. Interested candidates are welcome to contact us directly.
Supervision by Inês Cabrita […]
[Original post on social.cologne]
Alternative splicing and polyadenylation matter for Glomerular Disease! Great work by @shipraagarwal.bsky.social
#FSGS #rFSGS #podocyte
@asnkidney.bsky.social
@asnpublications.bsky.social
pubmed.ncbi.nlm.nih.gov/40397520/
More from the #podocyte2025 with @kidneyomicsamps.bsky.social and Laura Mariani
#podocyte #hamburg #FSGS #rFSGS #genetics #Nephsky #Medsky #Skyneph
@isgd.bsky.social
The enzyme SMPDL3b in podocytes decouples proteinuria from #chronickidneydisease progression in experimental #Alport Syndrome
doi.org/10.1016/j.kint.2025.04.024
#MedSky #NephSky #OpenAccess #CKD #glomerulardisease #sphingolipids #podocyte
Professor Ashley Jefferson, MD, shares information regarding the many advances in Minimal Change Disease in this Grand Rounds presentation on Diffuse Podocytopathy. #FSGS #MinimalChangeDisease #Podocyte #NephSky
@uwmedicine.bsky.social
Watch - youtu.be/lhy-p1212TI
C3 Glomerulopathy #podocyte puzzles @kdjhaveri @ERAkidney @CKJsocial www.era-online.org/publications/c3-glomerul...
Podocytologists of the Bluesky world, unite! @rachellennon.bsky.social @rheaultm.bsky.social Anymore out there (yet)? #podocyte #AlportSyndrome
Check out the next #podocyte puzzles @CKJsocial academic.oup.com/ckj/article/17/1/sfad278... ANCA vasculitis @KateIsabelle24
Hi! Cristina Popa, Romanian nephrologist, and proud captain of pod 1 #PodOcyte hosting tonight #Nephjc
@NSMCInternship
Here is a memory from the first times I understood what’s up with hyponatremia 😍
Urinary levels of podocyte-derived microparticles are associated with the progression of chronic kidney disease http://atm.amegroups.com/article/view/29415 #podocyte
#POCUS training , #Onconephrology #cardiorenal service inpatient #obnephrology amazing icu experience , #GN center in Long Island #podocyte research #pathology diverse , great research opportunities
Faculty Spotlight: Pravin Singhal, world known #podocyte researcher, well funded lab for over 25 years, HIV Nephropathy, APOL1 related renal disease, and in addition a superb clinician and educator. Former chief of this division, almost 300...
