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A breakthrough therapy for stroke survivors to help improve upper‑limb function through vagus nerve stimulation (VNS) paired with rehabilitation is now available at Sanford Health Bismarck.

buff.ly/TTkimnV

#MED #SanfordBismarck #VNS #Vivistim #IschemicStroke

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Researchers map the interplay of #ProgrammedCellDeath after #IschemicStroke, showing early #ferroptosis and #necroptosis followed by #apoptosis, with iron driving both—highlighting the potential of concurrently targeting multiple death mechanisms.

Read: doi.org/10.1016/j.ge...

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Crosstalk among Oxidative Stress, Autophagy, and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells: A Mixed Computational and Experimental Study

Crosstalk among Oxidative Stress, Autophagy, and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells: A Mixed Computational and Experimental Study

#Ginsenoside Rb1 protects BMECs from #Ischemia-reperfusion injury by regulating #Autophagy, #Apoptosis, and #OxidativeStress via SQSTM1/p62, ATG5, and HIF-1α, highlighting these as potential #TherapeuticTargets for #IschemicStroke.
Read: doi.org/10.1007/s115...

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In a new study published in Translational Dental Research, a team of researchers from China introduced a "theragnostic" agent that combines therapy and diagnosis. Learn more: https://ow.ly/tiIB50XZWIB
#teeth #stemcells #QuantumDots #IschemicStroke

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The Neuroprotective Mechanisms of Kaempferol in Experimental Ischemic Stroke: A Preclinical Systematic Review Can plants protect stroke victims? Study finds kaempferol’s antioxidant properties reduce brain injury. #IschemicStroke #Kaempferol

Can plants protect stroke victims? Study finds kaempferol’s antioxidant properties reduce brain injury. #IschemicStroke #Kaempferol
www.rimpacts.com/rd/p?c=10092... 📄DOI: doi.org/10.1007/s120...

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Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9): The Multifaceted Biology, Diseases, and Pharmaceutical Interventions Summary of PCSK9 inhibitor mechanisms. PCSK9 inhibitors (PCSK9-i) primarily lower LDL-cholesterol (LDL-C) by blocking PCSK9-mediated degradation of hepatic LDL receptors (LDLR), enhancing LDL clearan....

#Review in #MedComm
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9): The Multifaceted Biology, Diseases, and Pharmaceutical Interventions doi.org/10.1002/mco2...

#PCSK9 #LDL_C #IschemicStroke #Intervention #Strategies #PrecisionTherapy #therapeutics

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Donate to Help Carmen's Children Lay Her to Rest in the Philippines, organized by Carmen's Children A Final Goodbye: Bringing Our Mother Home to the Philippines … Carmen's Children needs your support for Help Carmen's Children Lay Her to Rest in the Philippines

My mom died after being comatose for 6 days. I'm heartbroken 💔

#ischemicstroke #grieving

gofund.me/d69122ac0

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New research from @uhn.ca's @kbi-uhn.bsky.social reveals that inhibiting an enzyme called SKI-1 may protect the brain after #IschemicStroke by preserving blood vessel integrity. 🧠 This discovery could lead to new targeted therapies that improve recovery.

🔗: www.uhnresearch.ca/news/brain-b...

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Telestroke and Timely Treatment and Outcomes for Acute Ischemic Stroke This cohort study evaluates the association of telestroke use with time to treatment and outcomes among patients with acute ischemic stroke in Michigan.

Pacientes con ictus isquémico agudo elegibles para trombolisis evaluados c/conexión a especialistas en ictus tienen probabilidad 61% mayor de recibir trombolisis pero 44% menos de cumplir c/tiempos hasta adm TTO según las guías de 60 min #telestroke #ischemicstroke jamanetwork.com/journals/jam...

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Ischemic Stroke Market Size, Growth Analysis, Report 2035 Ischemic Stroke Market Industry is expected to grow from Billion USD 5.27 Billion USD in 2025 to 9.80 Billion USD till 2035, at a CAGR (growth rate) is expected to be around 7.13% during the forecast ...

🧠 New interventions fuel growth in the #IschemicStroke treatment market! Full analysis: 🔗 www.marketresearchfuture.com/reports/isch...

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Update/Herstory for those new to me:
We’ve now been in a motel for 63 days (should be drama-free now), waiting on accessible housing for my mom (79, full-time #wheelchair user), my sister (50, semi-paralyzed on left side from a May #ischemicstroke, still w/o rehab),

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Vitamin D Activates Nrf2 to Prevent Nerve Injury and Reduce Brain Damage in Acute Cerebral Infarction - Current Medical Science Objective This study aimed to investigate the neuroprotective effects of cholecalciferol cholesterol emulsion (CCE), a vitamin D (VD) precursor, in a murine model of acute cerebral infarction (ACI)…

This study elucidates the therapeutic potential of a Vitamin D precursor, CCE, in the treatment of #IschemicStroke and the importance of Nrf2 in mediating its neuroprotective effects. #medsky

Click:

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Temporal and Spatial Dynamics of Ischemic Stroke Lesions after Acute Therapy: A Comprehensive Edema Assessment Using Combined <sup>1</sup>H- and <sup>23</sup>Na-MRI <p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" dir="auto" id="d7323527e227"> <b> <i>Introduction:</i> </b>...

📄 'Temporal and Spatial Dynamics of Ischemic Stroke Lesions after Acute Therapy: A Comprehensive Edema Assessment Using Combined 1H- and #23NaMRI' - an article in the @kargerpublishers.bsky.social research collection on #ScienceOpen:

🖇️ #IschemicStroke #SodiumMRI #StrokeImaging #VascularNeurology

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Crosstalk among Oxidative Stress, Autophagy, and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells: A Mixed Computational and Experimental Study

Crosstalk among Oxidative Stress, Autophagy, and Apoptosis in the Protective Effects of Ginsenoside Rb1 on Brain Microvascular Endothelial Cells: A Mixed Computational and Experimental Study

#GinsenosideRb1 protects brain microvascular endothelial cells against oxygen-glucose deprivation/reperfusion injury by influencing oxidative stress, apoptosis, and autophagy, thereby establishing its potential as a #TherapeuticAgent for #IschemicStroke. #medsky

Read: doi.org/10.1007/s115...

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Scientists reveal that Casr-related #neuroprotection induced by ischemic preconditioning (IP) is associated with the transformation of M2 microglia, providing new insights into IP-mediated neuroprotection against #ischemicstroke. #medsky

Read more: link.springer.com/article/10.1...

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Italy Ischemic Stroke Surgery Market Size, Growth Report 2035 Italy Ischemic Stroke Surgery Market Industry is expected to grow from 102(USD Million) in 2025 to 204 (USD Million) by 2035. The Italy Ischemic Stroke Surgery Market CAGR (growth rate) is expected to...

🧠 Minutes matter! #StrokeSurgery in Italy adopts neurovascular innovations for faster recovery & brain preservation.
#NeuroSurgery #StrokeAwareness #Thrombectomy #ItalyHealthTech #IschemicStroke

www.marketresearchfuture.com/reports/ital...

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Another of my friend who had fallen in the #Covid trap a month ago & till in 🏥 with ME . Now paralyzed from the neck down in this 2ndly reinfection .1st reinfection caused #ischemicstroke related #Neurocovid . Be careful out there people …

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#Medsky🧪#IDsky #cardiosky #Atherosclerosis is the focal accumulation of lipids, fibrous tissue & cells in the intimal layer of arteries. The disease develops over decades and may suddenly manifest as #myocardialinfarction or #ischemicstroke, which are leading causes of death in the world…

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This study provides mechanistic insights on how Casr inhibition-mediated M2 microglial transformation during #IschemicPreconditioning exerts #neuroprotective effects against #IschemicStroke. #Stroke #medsky

Read: link.springer.com/article/10.1...

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#Medsky🧪#Neurosky #pharmasky #drugdelivery #Ischemicstroke affects millions of people annually with limited treatment options targeting #excitotoxicity, a major cause of cognitive impairment. The PSD-95 inhibitor NA-1 has demonstrated neuroprotective potential,

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Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale | Stroke BACKGROUND: The incidence of young-onset ischemic stroke is rising, driven by cryptogenic ischemic stroke (CIS) and patients without vascular risk factors. This study examines the burden and associati...

Factores de riesgo tradicionales contribuyen al ictus isquémico criptogénico sin foramen oval permeable, los no tradicionales parecen más críticos en los que lo tienen permeable, migraña con aura c/papel prominente en las mujeres #ischemicstroke #foramenovale www.ahajournals.org/doi/10.1161/...

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Poststroke Lingual Function and Swallowing Physiology Purpose: Poststroke dysphagia is characterized by deficits in lingual function. However, correlations between lingual function and oral and phary...

#JSLHR researchers explored if tongue pressure generative capacity in patients after ischemic stroke is associated with oropharyngeal #swallowing impairments. on.asha.org/4lLXjjL @sigperspectives.bsky.social @csdisseminate.bsky.social #SLPeeps #IschemicStroke

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Iron promotes both ferroptosis and necroptosis in the early stage of reperfusion in ischemic stroke

Iron promotes both ferroptosis and necroptosis in the early stage of reperfusion in ischemic stroke

Mechanistic insights on how iron-mediated #RedoxImbalance potentiates #Necroptosis via the RIPK1-RIPK3-MLKL pathway & increases susceptibility to #Ferroptosis in the early stages of #IschemicStroke (IS). #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

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#LoneStarstroke #Texas #Stroke #IschemicStroke #Afib #DaiWaiOlson Congratulation Dr. Steven J. Warach and Lone Star Stroke Research Team for their recent publication on Jama! Click to the link read jamanetwork.com/journals/jam...

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#SpatialTranscriptomics #Proteomics acute stage of #IschemicStroke (🐭tMCAO 24h)

Molecular drivers of mural cell hyperconstriction & BBB disintegration in post-stroke futile reperfusion?
A dual non-neuronal role of Calcineurin?

@chrstaehr.bsky.social #Stroke 2025
www.ahajournals.org/doi/10.1161/...

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Key point: Following an incident ischemic stroke admission, 78% were initiated on non-enzyme-inducing ASMs, and levetiracetam (42%) was the most dispensed initial ASM.
onlinelibrary.wiley.com/doi/full/10....

#epilepsy #ilae #antiseizuremedication #ischemicstroke #poststrokeseizure

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Stroke and myocardial infarction with contemporary hormonal contraception: real-world, nationwide, prospective cohort study Objective To evaluate the association between contemporary hormonal contraceptive use and the risk of incident ischaemic stroke and myocardial infarction. Design Real-world, nationwide, prospective c...

#Medsky🧪 #obgynsky #womenhealth #publichealth Certain hormonal contraceptives are associated with a greater risk of #ischemicstroke & #myocardialinfarction, or #heartattack
@bmj.com
www.bmj.com/content/388/...
The study found that the combined estrogen-progestin pill

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#EPI
Epigenetics is key in ischemic stroke research. Our study maps global trends and highlights emerging areas. 🧠🔍
@GenomeFi

#ischemicstroke #globaltrends
Details: maxapress.com/article/doi/...

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Key point: SAI and ES partially mediated the relationship between stroke severity and PSE.
doi.org/10.1111/epi....

#epilepsy #ilae #earlyseizure #infection #ischemicstroke #mediationanalysis #poststrokeepilepsy

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Iron Overload: Accelerator of Deadly Cell Responses in Stroke | Newswise A pivotal study has uncovered that iron orchestrates the activation of two damaging cell death pathways—ferroptosis and necroptosis—early in ischemic stroke recovery, exacerbating brain injury. This d...

Iron Overload: Accelerator of Deadly Cell Responses in Stroke

www.newswise.com/articles/iro...

#DrugAddiction #DrugTherapy #ischemicstroke #stroke

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