Dr. Kizil and his team at Columbia University Medical Center in New York City will develop a first-in-class precision therapy that targets accumulation of the protein fibronectin and subsequent neuroinflammation at its source before irreversible damage and cognitive decline occur. This therapy could offer safer, genetically informed, and personalized treatment options for patients carrying the APOE-ε4 allele, which is the strongest genetic risk factor for Alzheimer’s disease.

Caghan Kizil, PhD was awarded a #CureOneCureMany Catalyst Award in #Neuroinflammation.

Institution: @columbiauniversity.bsky.social

This $500K award is funded with the National MS Society, Gates Ventures, NFL Players Association, Genentech, and WoodNext Foundation.

buff.ly/DbqbFwN

Dr. Bennett and her team at Children’s Hospital of Philadelphia in Pennsylvania will coordinate three different laboratories to study the neuroimmune mechanism of how microglia—the brain’s immune cells, which trigger neuroinflammation—transition into an early form called ISGMs (interferon-stimulated gene-expressing microglia). This could lead to new therapies that replace and engineer microglia to treat potentially hundreds of brain diseases.

Mariko Bennett, MD, PhD was awarded a #CureOneCureMany Catalyst Award in #Neuroinflammation.

Institution: @childrensphila.bsky.social

This $500K award is funded with the National MS Society, Gates Ventures, NFL Players Association, Genentech, and WoodNext Foundation.

buff.ly/UdGenVL

Dr. Rowitch and his team will study neuroinflammation and its role in multiple sclerosis, particularly regarding neurons that express the genetic marker CUX2. They will identify pathways for clinical intervention and develop approaches to enhance DNA repair after damage from neuroinflammation.

David Rowitch, MD, PhD was awarded a #CureOneCureMany Breakthrough Award in #Neuroinflammation.

Institution: Cedars-Sinai Medical Center

This $2 million award is funded with the National MS Society, Gates Ventures, NFL Players Association, Genentech, and WoodNext Foundation.

buff.ly/IilNUxn

Dr. Dhindsa and his team, based at Baylor College of Medicine in Houston, Texas, will leverage AI to analyze millions of gigabytes of data and identify human genetic variations that increase the risk of virally triggered Alzheimer’s disease and neuroinflammation. These studies could enable new antiviral and vaccination strategies to treat Alzheimer’s.

Ryan Dhindsa, MD, PhD was awarded a Breakthrough Award in #Neuroinflammation.

Institution: @bcmhouston.bsky.social, @bcmfromthelabs.bsky.social

This award is funded with the National MS Society, Gates Ventures, NFL Players Association, Genentech, and WoodNext Foundation.

buff.ly/d9mczdm

One week left to submit your proposal for #GLIA2027, Bologna, 7–10 July 2027.

Deadline: 8 April 2026, 12:00 p.m. CEST
Submit: https://www.glia-meeting.eu/2027/call-for-symposia/

#GlialCells #Astrocytes #Microglia #Oligodendrocytes #SchwannCells #NG2Cells #Neuroinflammation #Myelination

Introducing Recipients of the American Brain Foundation Cure One, Cure Many Awards - American Brain Foundation Meet the recipients of 2026 Cure One, Cure Many Awards and discover how their work is finding connections that could lead to cures.

Read about the recipients of the latest American Brain Foundation Cure One, Cure Many Awards in our latest blog! In the largest distribution of funding in ABF history, six researchers and their teams will study #neuroinflammation and #LewyBodyDementia. ⬇️ buff.ly/J98m8gY

The Role of Phospholipases, Cyclooxygenases, and Lipoxygenases in Cerebral Ischemic/Traumatic Injuries

www.dl.begellhouse.com/journals/7b0...

#Neuroinflammation #BrainInjuryResearch #PhospholipasePathways #CRN

neurovascular disruption contribute to gray matter loss.
- #COVID related #neuroinflammation & #hypoxia target vulnerable regions
- #COVID ➡️ 🧠 changes driven by neuroinflammation, hypoxia,microvascular injury with the hippocampus,thalamus, insula & frontal cortex repeatedly identified as susceptible

#Hypoxia-inducible protein 2 mediates metabolic adaptation of Ly6ChighLy6Glow #monocytes after #stroke. New study from Weijie Chen, Xin Wang, Tingting Huang, Weifeng Yu, Florent Ginhoux, Peiying Li (Shanghai Jiao Tong University) and colleagues:
rupress.org/jem/article/...

#Neuroinflammation

Awesome discussion for those of us who love resident #macrophages in all their forms, and wonder what allows some to be be self renewing
#neuroskyence #immunosky #glia #neuroinflammation

It's a brain map that represent a pinky brain with highlighted areas. Neurological Map of Cognitive and Emotional Independence. A professional medical illustration of the human brain in both lateral (side) and sagittal (cross-section) views, specifically color-coded to show the "Resistance Circuit" involved in maintaining autonomy against manipulation and psychopathic influence. Key Anatomical Regions and Labels: Red (Prefrontal Cortex / PFC): Located at the front of the brain. Labeled as the "Command Center" for executive function and logical reasoning. Blue (Dorsomedial Prefrontal Cortex / dmPFC): Located in the upper-middle PFC. Labeled for tracking social discrepancies and maintaining independent opinion. Yellow (Anterior Insula): Deep within the lateral sulcus. Labeled as the "Gut Instinct" and social boundary detector (the "Cringe" response). Green (Amygdala): A small almond-shaped structure in the temporal lobe. Labeled for emotional response and social signal processing. Purple (Anterior Cingulate Cortex / ACC): Located on the inner surface. Labeled for conflict resolution between logic and emotion. Functional Visuals: The Link: Large green double-headed arrows indicate "Strong Functional Connectivity" between the PFC (Logic) and the Amygdala (Emotion), illustrating a regulated emotional state. The Guide: A sidebar table summarizes the "Functional Map Guide," matching the colors to their cognitive roles. Practical Application: A bottom-right panel titled "How to Use the Map" provides cognitive prompts for each region, such as "Red: Ask 'Is it factually true?'" and "Yellow: Pay attention to boundaries (chest tightness)." Academic Context: The image serves as a pedagogical tool for understanding how neuroplasticity and connectivity in the frontal and temporal lobes contribute to psychological resilience.

Curious insights to some general queries for comparisons when thinking about toxic human relationships and brain circuits to be trained and protected. #Resolving
#NeuroCovid-19 #Neuroinflammation #Neuroplasticity
@academicabuse.com, @mindasmulheres.bsky.social.
doi.org/10.1016/j.jp...

🎨Science Visuals | 🧠#Meningitis is an inflammation of the #brain and spinal cord membranes that can progress rapidly
Timely recognition+medical intervention are critical to prevent severe complications
#PublicHealth #InfectiousDiseases #Neuroinflammation #MeningitisOutbreak #Kent #MedicinalChemistry

🧨TNF‑α
Repeatedly elevated in studies linking #longCOVID to:
- Depression and anxiety
- Cognitive problems (direct neural effects shown in human neuron models)
* #Brainfog & #neuroinflammation
- Long-term cognitive impairment

Coronavirus disease 2019 and its impact on the cognition of older adults: Unraveling the role of inflammation The Coronavirus Disease 2019 (COVID-19) pandemic significantly impacted the older adult population globally. This study aimed to investigate cognitive…

This allows peripheral immune signals or inflammatory mediators to enter the CNS, further fueling #neuroinflammation
www.sciencedirect.com/science/arti...

IL‑6,IL‑1β ,TNF‑α disrupt neurotransmission, glucocorticoid regulation & memory processes, mechanisms shared with major psychiatric disorders

These studies does not always evaluate “infectious biomarkers” as a formal category, but cytokines function in this role because they reflect persistent immune activation, #neuroinflammation & pathogen‑triggered signaling.

Research Associate in Inflammation Research:Oxford Road This full-time post is for up to 36 months, with an anticipated start date of the 1st of April 2026

🚨New job alert! Come join our growing ECR community and #neuroinflammation theme at the Jeff 🎉

We have an exciting post-doc opportunity to work on an MRC funded project studying inflammasomes in the lab of Prof David Brough.

More info & how to apply here: www.jobs.manchester.ac.uk/Job/JobDetai...

⏳ Final call! Submit your scholarship or short talk abstract for Neuroinflammation in Health & Disease by March 18 (11:59 PM MST).

Hear why from @malutansey.bsky.social

🎥 youtu.be/rGvSAqvbNzA
🔗 keysym.us/KSNeuroInfla...

#KSNeuroInflam26 #neuroinflammation #neurobiology @kleinlabuwo.bsky.social

Although no study directly implicates LCN2 as a causal factor in #longCOVID #neuroinflammation, multiple reviews identify mechanistic pathways in LC that LCN2 is known to drive:
LCis characterized by BBB disruption, microglial activation, NET formation, NLRP3 activation, cytokine imbalance &

Online now: Comparisons in microglial responses to ischemic–hypoxic #braininjury in neonatal and adult mice analyzed by transcriptome integration and deconvolution #technologies. doi.org/10.4103/ATN.... #Microglia #Neuroinflammation #Transcriptomics #SingleCell #StrokeResearch #MedSky #neuroskyence

TDP-43 pathology triggers #neuroinflammation and #CognitiveImpairment by inducing microglial necroptosis, by S. Guo, C. Fu, Y. Yin, W. Cheng & colleagues at Xinhua Hospital, Shanghai

🗞️ doi.org/10.1038/s44321-026-00394-9

Covid, herpès, VIH: ces virus qui peuvent aussi troubler la mémoire | RTS Une méta-analyse menée à Genève, basée sur 931 études, montre que certaines infections virales peuvent s’accompagner de troubles de la mémoire, de l’attention ou de la concentration. En cause, pas for...

" Covid, herpès, VIH: ces virus qui peuvent aussi troubler la mémoire "

#NeuroInflammation

www.rts.ch/info/sante/2...

#Inflammation rewires the enteric nervous system through neurogenic #monocyte recruitment, say Sravya Kurapati, Changsik Shin, Krisztina Szabo, Milena Bogunovic @umasschan.bsky.social and colleagues: rupress.org/jem/article/...

#MucosalImmunology #Neuroinflammation #IBD

Neuroinflammation in Health and Disease | Keystone Symposia Join us at the Keystone Symposia on Neuroinflammation in Health and Disease, June 2026, in Whistler, with field leaders!

Explore emerging research with field leaders @keystoneSymposia.bsky.social #Neuroinflammation in Health & Disease, this June in Whistler! keysym.us/KSNeuroInflam26 #KSNeuroInflam26 www.keystonesymposia.org/conferences/...

Microglia Research Summary February 2026 - Summarized Science Summary of key Microglia publications highlighting major findings, clinical relevance, and emerging research trends.

🧫 Microglia - Feb 2026

• BTK inhibition reduces neuroinflammation in ALS models
• Microglia-T cell interactions drive neurodegeneration in Huntington's
• TGF-β inhibition in microglia stimulates adult neurogenesis

pir.sh/JoZa0Nr1Gy

#Microglia #Neuroinflammation

NIK-driven IL-23 production by #myeloid cells is a key factor in the development of autoimmune #inflammation. New study from Nishada S. Ramphal, Ari Waisman (@ariwaisman.bsky.social) and colleagues @mainzuniversity.bsky.social: rupress.org/jem/article/...

#Neuroinflammation #Autoimmunity

Central neurons encode interleukin-1β signals and mediate stress-induced #inflammation. New study from Okito Hashimoto, Tyler D. Hepler, Kevin J. Tracey, Sangeeta S. Chavan and colleagues @northwellhealth.bsky.social: rupress.org/jem/article/...

#Neuroinflammation #Cytokines

Microglial reactivity and neuroinflammation-driven changes in motivational behaviors are regulated by Orai1 calcium channels The Ca2+ channel Orai1 in microglia links systemic inflammation to depressive-like behaviors in mice.

How does #neuroinflammation trigger depressive-like behaviors?

Researchers in #ScienceSignaling show that #Orai1 sustains production of proinflammatory cytokines from microglia and that Orai1-deficient mice display less pronounced depressive-like behaviors. https://scim.ag/4rmJSZQ

Soluble c-Met correlates with NfL and GFAP levels in the CSF of patients with multiple sclerosis The hepatocyte growth factor (HGF)/c-Met pathway plays an important role in several inflammatory conditions, regulating phenotypic plasticity within b…

Soluble c-Met ↑ in CSF & plasma, CSF c-Met links to NfL/GFAP, plasma ADAM10 ↓. Suggests compartment-specific c-Met shedding in early MS. #MultipleSclerosis #Biomarkers #Neuroinflammation

Check the paper👇:

www.sciencedirect.com/science/arti...

Ramphal, Waisman et al. @mainzuniversity.bsky.social reveal that NIK drives neuroantigen-specific T cell priming by regulating antigen presentation and IL-23 production, identifying NIK as a key orchestrator of #myeloid-driven CNS #autoimmunity. rupress.org/jem/article/...

#Neuroinflammation

Antibiotic-induced gut microbiome remodeling reduces neuroinflammation in traumatic brain injury - Communications Biology Short-term oral antibiotics reshape the gut microbiome after single or repeated TBI in male mice, yet reduce lesion volume, apoptosis, gliosis, cytokines, and immune infiltration, revealing SCFA-indep...

Researchers, led by Dr. Sonia Villapol at Houston Methodist, found short-term antibiotic treatment significantly reduced #Neuroinflammation & #Neurodegeneration following #TraumaticBrainInjury by altering #Gut #Microbiome in animal models. @commsbio.nature.com 👉 www.nature.com/articles/s42...