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VIRULENCE (Estats Units) presenta nou single: "Epidemic Unleashed" #Virulence #DeathMetal #Abril2026 #EstatsUnits #NouSingle #Metall #Metal #MúsicaMetal #MetalMusic

DNA-binding protein blocks virulence cascade in a diarrhea pathogen outside hosts, study finds Some pathogens use temperature as a trigger and activate virulence only after entering the warmer environment of a host. A research team from Ruhr University Bochum, Germany, and the University of…

#DNA-binding #protein blocks #virulence cascade in a #diarrhea #pathogen outside hosts ...

| #bacteria | #microbiology | #Yersinia | #plague | #immunesystem | Via @sciencex.bsky.social

phys.org/news/2026-04...

Our latest manuscript explores capsule exchangeability & phenotypic portability

We didn’t directly address its role in #virulence
⏩️ that was already elegantly shown here—worth a look 👀👇🏻

doi.org/10.1371/jour...

🎯 Their results supports our plug-and-play model!

Bonus: we kept 🐭 alive

#microsky

Characteristics and capsule production of capsule-swapped strains. Genetic (lower triangle) and biochemical (upper triangle) relatedness between the different capsule types analyzed in this study. Biochemical similarity was calculated as the percentage of residues shared between two K types (# of shared unique oligosaccharides/# of different nonredundant oligosaccharides). Oligosaccharidic compositions and models were taken from K-PAM. Genetic relatedness was calculated taking into account all homologous genes between two K types. Monosaccharides composing the different capsules are depicted according to the Symbol Nomenclature for Glycans convention.

How do multi-gene systems evolve across genetic backgrounds without disruptive epistasis? @julielebris.bsky.social @olayarendueles.bsky.social &co show the #Klebsiella capsule locus is a plug&play module that swaps with low fitness cost while preserving #virulence @plosbiology.org 🧪 plos.io/4s64Ko0

Characteristics and capsule production of capsule-swapped strains. Genetic (lower triangle) and biochemical (upper triangle) relatedness between the different capsule types analyzed in this study. Biochemical similarity was calculated as the percentage of residues shared between two K types (# of shared unique oligosaccharides/# of different nonredundant oligosaccharides). Oligosaccharidic compositions and models were taken from K-PAM. Genetic relatedness was calculated taking into account all homologous genes between two K types. Monosaccharides composing the different capsules are depicted according to the Symbol Nomenclature for Glycans convention.

How do multi-gene systems evolve across genetic backgrounds without disruptive epistasis? @julielebris.bsky.social @olayarendueles.bsky.social &co show the #Klebsiella capsule locus is a plug&play module that swaps with low fitness cost while preserving #virulence @plosbiology.org 🧪 plos.io/4s64Ko0

Characteristics and capsule production of capsule-swapped strains. Genetic (lower triangle) and biochemical (upper triangle) relatedness between the different capsule types analyzed in this study. Biochemical similarity was calculated as the percentage of residues shared between two K types (# of shared unique oligosaccharides/# of different nonredundant oligosaccharides). Oligosaccharidic compositions and models were taken from K-PAM. Genetic relatedness was calculated taking into account all homologous genes between two K types. Monosaccharides composing the different capsules are depicted according to the Symbol Nomenclature for Glycans convention.

How do multi-gene systems evolve across genetic backgrounds without disruptive epistasis? @julielebris.bsky.social @olayarendueles.bsky.social &co show the #Klebsiella capsule locus is a plug&play module that swaps with low fitness cost while preserving #virulence @plosbiology.org 🧪 plos.io/4s64Ko0

Great to hear the full story of this exciting project that is done in collaboration with, among others, @mads-chem.bsky.social of our @led3hub.bsky.social. (2/2)

#ChemBio #ChemSky #Synthesis #SAR #Tuberculosis #Virulence #ABPP #PAL

#P4-ATPase Drs2 regulates #virulence, #stress adaptation, and #autophagy in #Candida glabrata
doi.org/10.1080/2150...
@tandfresearch.bsky.social

The #ORF6 accessory #protein contributes to #SARS-CoV-2 #virulence and pathogenicity in the naturally susceptible #feline model of infection

The #ORF6 accessory #protein contributes to #SARS-CoV-2 #virulence and pathogenicity in the naturally susceptible #feline model of infection, etidiohnew.blogspot.com/2026/02/the-...

Evolutionary #lineage and #host origin influence #virulence and #mammalian adaptation of #H7N9 avian #influenza viruses

Evolutionary #lineage and #host origin influence #virulence and #mammalian adaptation of #H7N9 avian #influenza viruses, etidiohnew.blogspot.com/2026/02/evol...

Today’s workflow: performing a uronic acid assay to quantify #capsular polysaccharide production in our #AMR bacterial isolates. Comprehensive phenotypic characterization beyond resistance profiling remains essential to understand key #virulence determinants.

We are editing a Special Issue on "Genomic Perspectives on the #Ecology and #Evolution of Bacterial #Plant #Pathogens and #Symbionts".
#Genomics #Pathogenicity #Virulence
#Acidovorax #Clavibacter #Curtobacterium #Erwinia #Pantoea #Pseudomonas #Ralstonia #Xanthomonas
www.mdpi.com/journal/micr...

How light suppresses virulence in an antibiotic-resistant pathogen Light is a universal stimulus that influences all living things. Cycles of light and dark help set the biological clocks for organisms ranging from single-celled bacteria to human beings. Some…

How #light suppresses #virulence in an #antibiotic-resistant #pathogen ...

| #antibioticresistance | #bacteria | #photosynthesis | #biofilms | #Pseudomonas | Via @sciencex.bsky.social

#JJC2026 François Delmotte (@inrae-save.bsky.social) on parallel #adaptation and admixture driving the #evolution of #virulence in the #grapevine downy #mildew #pathogen

How cholera virulence is activated: A long-sought structural explanation Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year. Caused by the bacterium Vibrio cholerae, ...

New structural insights show that cholera virulence genes are activated by stabilizing, rather than reshaping, the transcription machinery, offering potential targets for future therapies. doi.org/hbj5d4

phys.org/news/2026-01...
#biology #molecularbiology #cells #microbiology #cholera #virulence

#JJC2026 Kadiatou Schiffer-Forsyth (@umr-iam.bsky.social) on interactions between #virulence factors inferred from long-term monitoring of #poplar #rust

#JJC2026 Laurence Godiard (@lipme-toulouse.bsky.social) shows that a MADS-box transcription factor gene expressed in multicellular #appressoria impairs #Sclerotinia sclerotiorum #virulence on #Arabidopsis thaliana

#JJC2026 @jmaidment.bsky.social (@phimresearch.bsky.social) on structural characterisation of the interactions between #Magnaporthe oryzae MAX #effectors and their #virulence targets in #rice

Decoding the host-pathogen-environment interaction: Integrated insights into Helicobacter pylori virulence and epidemiological transmission

This review explores the mechanisms of #Hpylori #Pathogenesis, the host and environmental factors influencing its #Virulence, and its primary transmission routes to provide insights into its #Diagnosis and prevention. #MedSky

#OpenAccess: doi.org/10.1016/j.dc...

#Haemagglutinin 162-164 #deletions enhance #influenza B/Victoria virus #fitness and #virulence in vivo

#Haemagglutinin 162-164 #deletions enhance #influenza B/Victoria virus #fitness and #virulence in vivo, etidiohnew.blogspot.com/2026/01/haem...

Candida auris spreads globally as drug resistance and virulence increase, review finds The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new review by a Hackensack Meridian Center for Discovery and Innovation (CDI) scientist and…

#Candida auris spreads globally as drug resistance and #virulence increase ...

| #fungi | #DrugResistance | #pathogen | #publichealth | By @hackensackmeridianhealth.org via @sciencex.bsky.social

Rebecca Spanner is interested in developing and utilizing genomics resources of phytopathogenic fungi and their small-grain hosts. Her work focuses on understanding the evolution of #virulence and other traits that are important for the development and management of crop disease.

16/19🧵

New paper from the lab on how #virulence of human #pathogenic enterotoxigenic E. coli and V. cholerae can be attenuated using #binding #proteins: www.tandfonline.com/doi/full/10....
Thanks to great co-authors and funders!

The #α-glucosidase II #MaGls2 governs #virulence and #stress tolerance in #Metarhizium acridum by maintaining #cell wall architecture
doi.org/10.1080/2150...
@tandfresearch.bsky.social

(PDF) Impact of temperature on vegetative and pathogenic development of the fungal multi-host pathogen Lasiodiplodia theobromae (Pat.) Griffon & Maubl. PDF | Lasiodiplodia theobromae is an economically important multi-host plant pathogen infecting nearly 500 hosts, including perennial crops. In Peru, L.... | Find, read and cite all the research you n...

Impact of temperature on vegetative and pathogenic development of the fungal multi-host pathogen Lasiodiplodia theobromae (Pat.) Griffon & Maubl.

#Lasiodiplodia
#dieback
#sporulation
#temperature
#virulence

www.researchgate.net/publication/...

Bordetella hinzii Genomic Characteristics and Vaccine Target Discovery Analysis of the pathogenic traits of Bordetella hinzii, its antibiotic resistance mechanisms, virulence gene distribution, and vaccine development potential

This @ZoonosesJ study shows that Bordetella hinzii carries broad efflux-mediated #AntibioticResistance genes, conserved #virulence determinants, cross-host transmission potential, and highlights outer-membrane proteins LptD and BamD as promising #vaccine targets.

#OpenAccess: tinyurl.com/28gup4np

🔎 Spotted in #Virulence by @tandfresearch.bsky.social!
Researchers from #WSU Floyd College of Medicine used DSHB's anti-α-tubulin [AA4.3] mAb in a study on how the GCN-2 pathway triggers stress responses in C. elegans during infection.

📄 tinyurl.com/3anhfuhm

🧫 dshb.biology.uiowa.edu/AA4-3

Strain-Specific Virulence of Beauveria bassiana Vuill. (Hypocreales: Cordycipitaceae) on Tettigonia viridissima L. (Orthoptera: Tettigoniidae) | Radev | Agriculturae Conspectus Scientificus Strain-Specific Virulence of Beauveria bassiana Vuill. (Hypocreales: Cordycipitaceae) on Tettigonia viridissima L. (Orthoptera: Tettigoniidae)

Strain-Specific Virulence of Beauveria bassiana Vuill. (Hypocreales: Cordycipitaceae) on Tettigonia viridissima L. (Orthoptera: Tettigoniidae)

#Beauveria
#Hypocreales
#Cordycipitaceae
#entomopathogenicfungi
#biologicalcontrol
#hydrolyticenzymes
#virulence

acs.agr.hr/acs/index.ph...

Herpes virus-based vaccine shows promise in targeting tumors without side effects The Herpes simplex virus is a widespread virus that often causes cold sores, and most people carry it. By removing a virulence gene, i.e. a gene that makes the virus harmful to humans, the herpes…

#Herpes #virus-based #vaccine shows promise in targeting #tumors without side effects ...

| #virulence | #cancer | #proteoglycan | #angiogenesis | Via @sciencex.bsky.social