#Myeloid diversity in tumors: shaped by genes, location, and time. New review from Maria Nogales-Pons, Mariola Munárriz-Paños, Teresa Aceña-Gonzalo, & María Casanova-Acebes @casanova-acebes.bsky.social @cniostopcancer.bsky.social: rupress.org/jem/article/...
#CancerFocus #InnateImmunity
#Myeloid cells infiltrate tumors from early transformation to advanced disease; however, their plasticity complicates therapeutic targeting. In @jem.org, @casanova-acebes.bsky.social group reviews emerging technologies that uncover unexpected cellular states & functions rupress.org/jem/article/...
#Myeloid cells infiltrate tumors from early transformation to advanced disease; however, their plasticity complicates therapeutic targeting. Nogales-Pons et al. @casanova-acebes.bsky.social review emerging technologies that uncover unexpected cellular states & functions rupress.org/jem/article/...
NIK-driven IL-23 production by #myeloid cells is a key factor in the development of autoimmune #inflammation. New study from Nishada S. Ramphal, Ari Waisman (@ariwaisman.bsky.social) and colleagues @mainzuniversity.bsky.social: rupress.org/jem/article/...
#Neuroinflammation #Autoimmunity
Delve into recent JEM studies in the fields of #hematopoiesis and #myeloid lineages, incl. the role of neutrophils in myocardial & vascular injury, the characterization of intrarenal myeloid cells, a deeper understanding of the origin & function of #DendriticCells & more: rupress.org/jem/collecti...
Comprehensive Physiology | Review Spotlight 🔦 Discover the latest insights from Bhattacharyya et al. on the role of #myeloid cells in #PulmonaryFibrosis. 🫁 Explore how these cells impact disease progression and potential therapies. Read the full review: doi.org/10.1002/cph4...
To my friends who are @keystonesymposia.bsky.social #hematopoiesis and #myeloid meetings— please check out two talks from my group TOMORROW: Ruoqiong Cao on central #trainedimmunity Thursday morning and Arushana Maknojia unravels #microbiome dependent hematopoiesis in the pm! 🔥🔥🔥
Molecular and phenotypic blueprint of human #hematopoiesis links proliferation stress to #StemCell #aging. From Emanuele Lettera et al. @dimiccolab.bsky.social: rupress.org/jem/article/...
📘 In Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Tet2 deficiency–induced expansion of monocyte-derived #macrophages promotes liver #fibrosis. From Jiuxing Feng, Baitong Wu, Yujiang Geno Shi and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
pDCs amplify tissue-resident memory CD8⁺ T cell responses during viral reinfection. From Elena Hernández-García, Salvador Iborra and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Thymic myeloid cells are heterogenous and include a novel population of transitional #DendriticCells. From Matouš Vobořil, Kristin Hogquist and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
#Radiotherapy induces YTHDF2 in #DendriticCells impairing cross-presentation and T cell function, from Dapeng Chen, Chuan He, Hua Laura Liang, Ralph Weichselbaum et al: rupress.org/jem/article/...
📘 In #Hematopoiesis & #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Mechanometabolism instructs hematopoietic stem cell specification, from Paulina Horton, Pamela Wenzel and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
A #circadian checkpoint relocates #neutrophils to minimize injury, from Aroca-Crevillén, Hidalgo @drusqui.bsky.social and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Heart of the matter: #Neutrophils, #cancer, and #CardiovascularDisease. Review from Ambreen, McCarthy, Hidalgo, and @adrover.bsky.social: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated #macrophages in #lupus #nephritis. From Hoover, Hacohen, Davidson & colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis & #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
XPR1 regulates fetal liver #macrophage development, identity and pyrenocyte clearance. From Sebastian Stifter, Melanie Greter and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
See our collection of recent findings in the fields of #hematopoiesis and #myeloid lineages, including the role of #neutrophils in myocardial and vascular injury, the characterization of intrarenal myeloid cells, and more: rupress.org/jem/collecti...
Explore recent findings in the fields of #hematopoiesis and #myeloid lineages, including the role of #neutrophils in myocardial and vascular injury, the characterization of intrarenal myeloid cells, & more, to accompany @keystonesymposia.bsky.social meeting on the topic: rupress.org/jem/collecti...
Explore new #Immunology papers incl. antitumor T cell responses, intestinal #MucosalImmunology, metabolic adaptation in Th2 responses, #myeloid cells ontogeny & the impacts of #circadian checkpoints on their function, and local B cell alterations in #neuroinflammation. 👉 rupress.org/jem/collecti...
#ACUTE #MYELOID #LEUKEMIA
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#MANIA
allgraph.ro/advanced-sea...
MultiSearch Tag Explorer
aepiot.ro
#Myeloid cells 🤝 #Lymphoid cells!
Michelle von Locquenghien, Drs. Pascale Zwicky, Ken Xie, and Dr. Ido Amit's lab developed myeloid-targeted immunocytokines and NK/T cell enhancers that could potentially treat solid cancers.
📃@cp-cell.bsky.social - https://bit.ly/3Mkw3eM
🎧 - https://bit.ly/4pJvw4u
See what's to come in the December issue of ASH Clinical News! Highlights of next month's issue include articles on the past, present, and future of #hematology, rethinking the classification of #myeloid #neoplasms, early treatment in #MCL, and more: https://ow.ly/ngmg50XxL5o
#HemeSky
Join us for an all-star line up for the 2026 #KeystoneSymposia on #InnateImmunity, co-organised by @jkagan1.bsky.social & @brozlab.bsky.social A joint meeting with joint meeting with the Keystone Aging Symposium in beautiful Banff, Canada. Register now! #inflammasomes, #TLRs, #myeloid, #epithelia
PARPi and #myeloid #neoplasms; the Italian MITO-MaNGO experience based on a multicentric survey www.sciencedirect.com/science/arti... #hvhebron #onco [Text complet]
Scientists identify LILRB2/5 as receptors for #oligomeric #cystatinC, showing that this #amyloidprotein drives #myeloid immunosuppression, T-cell suppression, and #tumor progression, revealing a broader amyloid–LILRB interaction. #medsky
#OpenAccess #STTT: doi.org/10.1038/s413...
Vobořil, Hogquist @cfi-umn.bsky.social and colleagues reveal the #thymus as a niche for diverse, developmentally distinct #myeloid cells and elucidate their specific requirements for development and maturation. rupress.org/jem/article/...
#Hematopoiesis #Tolerance #LymphocyteBiology
#CCTG Trial Highlight for #LeukemiaAwarenessMonth : ALC8 is testing four innovative treatment combinations for newly diagnosed high-risk acute #myeloid #leukemia to find better first-line options for patients.
#myeloMATCH #SolvingCancerTogether
Trial info -> buff.ly/NLWIgT7
#Tasigna 200 mg Capsule (#3Nilotinib) is a targeted #cancer medicine used to treat chronic #myeloid #leukemia (#CML) in adults and children. It works by blocking abnormal proteins that drive cancer cell growth.
> www.drugsgeneral.com/tasigna-200-...
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➡️ older age, massive splenomegaly, high platelets, high LDH levels, biopsy exploration, bone marrow exploration --> #myeloid malignancies
➡️ thrombocytopenia, abnormal y-GT levels, presence of a monoclonal peak, liver biopsy exploration --> portal hypertension
