ECDO 2026 | Favignana – ECDO 2026 | Favignana

Join us at the 32nd ECDO Conference
“Death on the Beach: Cell Death & Disease” 🌊
📍 Favignana, Italy
📅 Sept 16–19, 2026

3 Nobel Laurates, 4 days of science, networking & Mediterranean vibes 🇮🇹

Don’t miss it!

#ECDO2026 #CellDeath #ScienceSA

ecdo2026.com

8/
Thanks to all the authors!
Happy to discuss and collaborate.

#Entosis #CellDeath #CancerBiology #Cytoskeleton #ROCK1 #PLS3

🎆 Happy new year and our first 2026 issue is out!
Cover: #epiblast development

👉Perspective: biological clocks
👉Review: #mitosis #CellDeath #inflammation
🔬 #chromatin #cancer #Bcells #Tcells #autophagy #organoids #mechanobiology #TranscriptionFactors #Xist & more!

www.nature.com/ncb/volumes/...

Client Challenge

This week #JournalClub @labsoap.bsky.social @nature.com #celldeath #plasmamembrane #rupture #MLKL #necroptosis www.nature.com/articles/s41...

We have an interesting observation (one data figure with several experiments) regarding one of the commonly used tools, which we believe might be important for the #CellDeath community. Which of cell death/immunology journals still publish article types such as "Correspondence", "Brief reports" etc?

Steady and escort cyst cells regulate #Drosophila germline stem cell differentiation and death, say Aya Ben-Hamo-Arad, Hila Toledano and colleagues (University of Haifa): rupress.org/jcb/article/...

#CellDeath #StemCells

bims-cediti 2025-12-21 papers

A weekly issue of Biomed news on everything related to #CellDeath, with some additional papers on other aspects of innate immunity and host-pathogen interactions:
biomed.news/bims-cediti/...

Primary cilia do more than sense signals. This review shows how they regulate cell death pathways in response to diverse stimuli, shaping development, tissue homeostasis, and disease.
🔗 www.sciopen.com/article/10.2...
#PrimaryCilia #CellDeath #SciOpen #TUP @tsinghuauniversity.bsky.social 🧪🌏 🌐

Great news for the #FERROPath consortium! The Federal Ministry of Research, Technology, and Space (BMFTR) is extending funding for two more years.

👉 t1p.de/taddg

@onderyildirimcpc.bsky.social @uniregensburg.bsky.social @tudresden.bsky.social @unidue.bsky.social

#CellDeath

Fig. 1 Iron-catalyzed radical formation and scavenging during lipid peroxidation.

At the (tz) border: glycoprotein trimming in the #Golgi apparatus prevents ferroptotic #CellDeath in #root tips

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...

👆 #Commentary by von Schaewen & Koiwa on Li et al. 👇

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...

#LatestIssue #PlantScience

One other recent RIP work is www.nature.com/articles/s41..., a paper that describes how viruses like #HSV1 and #InfluenzaA disrupt transcription, resulting in the expression of #ZRNA (a unique form of RNA), and that leads to #CellDeath, which is believed to be an #antiviral mechanism of the host.

🧪 the landscape of cell death is online! Spent half a year in Seattle, WA in @drewoberst.bsky.social `s lab, where we came up with a new way to conceptualize cell death commitment, similar to Waddington's famous landscape of lineage commitment! Thanks TJ and Andrew! #celldeath (free access👇)

bims-cediti 2025-11-30 papers

A traditional weekly issue of BioMedNews on everything #CellDeath -related:
biomed.news/bims-cediti/...

Necrosis Inhibitors To Pause The Diseases Of Aging -
Dr. #CarinaKern Ph.D. - CEO, #LinkGevity joins me on Progress, Potential, And Possibilities #BlueprintTheoryOfAging #BiologicalResilience #AntiNecrotic #CellDeath #PathoPathways www.youtube.com/watch?v=z4rf...

🧬 How cell death shapes craniofacial development
This review explores apoptosis, necroptosis, autophagy, and ferroptosis, showing how they interact with BMP, FGF, and WNT to guide organ morphogenesis. www.sciopen.com/article/10.2...

@tsinghuauniversity.bsky.social #TUP #CellDeath #Science

Towards a molecular and structural definition of cell death Nature Structural & Molecular Biology - Cell death contributes to tissue homeostasis and plays critical roles in inflammation and host defense. Our increasing understanding of the physiological...

Cracking the #CellDeath code! What has the field recently discovered, and what is on the horizon? Delighted to contribute to this article in #NatureStructuralMolecularBiology!
#Immunology #NatureSMB #Inflammasomes
rdcu.be/eG1Nm

RIOK2 kinase regulates the translocation of the FADD–RIPK1–Caspase-8 complex to the ER and the cleavage of Gasdermin D to drive pyroptosis - Nature Communications Macrophage infection by Yersinia or specific stimulations trigger caspase-8-mediated GSDMD cleavage. RIOK2 kinase is essential for this process by interacting with FADD and driving the lysosome-to-ER ...

This week´s issue of BiomedNews on everything related to #CellDeath and its consequences: biomed.news/bims-cediti/...
Some highlights:
RIOK2 as potentially new regulator of caspase-8 dependent pyroptosis following Yersinia infection:

SIGLEC12 mediates plasma membrane rupture during necroptotic cell death - Nature CRISPR–Cas9-based genome-wide screening shows that SIGLEC12 mediates plasma membrane rupture in cells undergoing necroptosis, possibly through a human-specific mechanism, indicating its potential as a...

This week is particularly remarkable in terms of #CellDeath and infection biology-related discoveries: biomed.news/bims-cediti/...
Highlight 1: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death:

#ApoptosisvsNecrosis31
#CellDeath #Pathology #MedicalEducation #Caspases #ProgrammedCellDeath #Bcl2 #MitochondrialPathway #ExtrinsicPathway #IntrinsicPathway #CoagulativeNecrosis #LiquefactiveNecrosis #GangrenousNecrosis #CaseousNecrosis #FatNecrosis #FibrinoidNecrosis #Histopathology #MedicalNotes

Single-cell analysis reveals cell death as driver of NLRP3-mediated secretion of IL-1β in human monocytes - Nature Immunology Lamkanfi, Shirasaki, Izawa and colleagues show that IL-1β release in human monocytes stimulated with lipopolysaccharide or carrying NLRP3 activatory mutations is mostly restricted to cells undergoing ...

Even rare #CellDeath events matter: a new study from Lamkanfi lab shows that small fraction of pyroptotic monocytes accounts for the most of IL-1β production following LPS stimulation, challenging the previously proposed models of IL-1β secretion from the living cells:

It's always a pleasure to spend the day out with the lab. Today was all about sharing our research and hearing about the other work going on in the department.

I was able to share and get valuable feedback on our latest insights on NINJ1 in #celldeath and #inflammation.

Structural insights into the atypical filament assembly of pyrin domain-containing IFI16 | The EMBO Journal imageimageThe pyrin domain (PYD)-containing interferon-inducible protein 16 (IFI16) has various inflammasome-independent functions, while it has also been suggested as a DNA sensor for inflammasome fo...

This week´s issue of Biomednews on everything related to #CellDeath: biomed.news/bims-cediti/...
Highlight of this week: Structural insights into the atypical filament assembly of pyrin domain-containing IFI16, and its difference from inflammasome-forming PYDs:

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple...

🧬 Just published in Advanced Science: New work from @linkermannlab.bsky.social showing that secondary necrosis can occur without Gasdermin E. A clear step forward in decoding regulated necrosis. #CellDeath #SecondaryNecrosis #GSDME #CaspaseInhibition #AdvancedScience #EditorPick shorturl.at/ITJe6

🔗To the original publication: t1p.de/jqhuo

#CellDeath #CancerResearch #Alzheimer #Parkinson #Neurodegeneration #PrecisionMedicine #HeartDisease #BNMRZ

New Switch for Natural Cell Death Identified

New Switch for Natural Cell Death🧬

Programmed cell death (#apoptosis) protects us, but cancer cells can evade it. Researchers at #HelmholtzMunich & TUM discovered a new molecular switch controlling this process.

👉 t1p.de/3fxvc

@tum.de @natureportfolio.nature.com

#CellDeath #BNMRZ

bims-cediti 2025-10-19 papers

Over the past few months, I started to curate a weekly issue of the weekly issue of the BioMed News @biomednews.bsky.social on #CellDeath.
Highlight of this week: further mechanistic clarification of how viral infections can drive endogenous Z-NA production: www.nature.com/articles/s41...

REVIEW🚨
The authors discuss the regulation and interplay of the metabolic #CellDeath pathways #ferroptosis, #disulfidptosis and #cuproptosis and explore how these mechanisms can be harnessed for cancer therapies.
@mdanderson.bsky.social
📖 ⬇️
https://bit.ly/3L3vN

6/9 But this trigger has a dark side.

Randal #Halfmann, who oversaw the work, observed that these #proteins don't always wait for a virus.

Given enough time—over a lifespan—they will spontaneously crystallize on their own. This misfire leads to #CellDeath and #inflammation.

#Science

what do u know about #celldeath or #cancer
upcoming episode in the future

Was such a nice mix day with PhDs in different domains Marya Savyuk and Deba_ 💫🙌🏻

'Death fold' proteins can make cells self-destruct. Scientists want to control them Scientists are hoping to treat diseases including cancer and Alzheimer's by influencing how cells make life-or-death decisions. (Image credit: faithiecannoise/iStockphoto)

'Death fold' proteins can make cells self-destruct. Scientists want to control them #Science #Biology #CellBiology #CellDeath #ProteinEngineering #Biotechnology