Review Links Adverse Cardiovascular Effects with Exposure to Pyrethroid Pesticides - Beyond Pesticides Daily News Blog Synthetic pyrethroids, as shown in a literature review of scientific research, can cause adverse cardiovascular effects.

A new literature review links #pyrethroid #insecticide #exposure to #cardiac #dysfunction, as the authors find emerging evidence indicating that #pyrethroids induce adverse #cardiovascular effects through pathways of #inflammation, #oxidativestress, and #myocardial injury. ➡️ Blog: ow.ly/PQCm50YE0Ux

why are you here?

#originalcharacter #oc #ocartist #myocardial #characterdesign #art #myart #digitalart

Revisiting the burden and patterns of myocardial infarction in type 1 diabetes Type 1 diabetes confers a cardiovascular burden that is often obscured by the young age of affected individuals and by the longstanding focus on microvascular rather than macrovascular complications. ...

Angelo Avogaro & Gian Paolo Fadini comment on:
Revisiting the burden and patterns of #myocardial #infarction in type 1 #diabetes www.thelancet.com/journals/lan... #T1D #MI #CVD

#MedSky #EndoSky #CardioSky

Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation myocardial infarction in type 1 diabetes in Finland: a nationwide cohort study We report that STEMI and NSTEMI exhibit different incidence patterns depending on age and year of myocardial infarction. STEMI and NSTEMI also differed regarding risk profiles, demonstrating that myoc...

New—Comparison of incidence patterns and risk profiles of ST-elevation and non-ST-elevation #myocardial #infarction in type 1 #diabetes in Finland: a nationwide cohort study www.thelancet.com/journals/lan... #T1D #MI #CVD

#MedSky #EndoSky #CardioSky

Mast Cells Contribute to Pressure Overload-Induced Myocardial Hypertrophy by Upregulating TRPV4 via Histamine: Role of Ca2+/ CnA/NFATc3 Signaling Pathway

This study shows that #Histamine-driven #TRPV4 upregulation in #Cardiac #MastCells enhances #CalciumInflux, activating #Ca²⁺/CnA/#NFATc3 signaling and contributing to #Myocardial #Hypertrophy and #CardiacRemodelling. #medsky

To read: doi.org/10.1007/s115...

#Exercise promotes #myocardial #angiogenesis, yet knowledge of molecular responses with different exercise modalities is limited. This new Scoping Review examines biomolecular regulators of myocardial/#coronary angiogenesis across exercise types in healthy animal models.

Single intramuscular injection of self-amplifying RNA of Nppa to treat myocardial infarction Self-amplifying RNA (saRNA) enables sustained protein expression from a single administration. In this study, we developed an intramuscular saRNA-lipid nanoparticle (saNppa-LNP) therapy encoding natri...

#Myocardial #infarction: self amplifying RNA for heart protective hormone delivered by intramuscular injection of lipid nanoparticles. Encouraging results in animal trials. www.science.org/doi/abs/10.1...

Timo Mohr and colleagues from @unibonn.bsky.social employed efficient in vivo targeting of the #myocardial scar using Moloney murine leukaemia virus complexed with #nanoparticles 🫀 🧲

📜 Read their #Research here: physoc.onlinelibrary.wiley.com/doi/10.1113/...

#Medsky🧪 #IDsky #immunosky #publichealth @jama.com In this self-controlled case series study of 11 887 patients, the risk of #cardiorespiratory events post RSV related hospitalization (especially during the first 2 weeks), including #myocardial #infarction, #stroke,

#Research
Uridine-Cytidine Kinase 2 (#UCK2)/Uridine-Cytidine Kinase Like 1 (#UCKL1) complex exacerbates the differentiation of myocardial fibroblasts via #TRIM21/#Smurf2/#Smad3 pathway after myocardial infarction doi.org/10.1186/s435...

#Myocardial #Infarction #fibroblast

Jianpi Qinghua Formula Alleviates Diabetic Myocardial Injury Through Inhibiting JunB/c-Fos Expression

The Jianpi Qinghua formula alleviates #DiabeticCardiomyopathy by reducing #myocardial #apoptosis and inflammation while improving #cardiac structure and function, underscoring its therapeutic potential in #diabetes‑related #HeartInjury. @ShanghaiUni_TCM
Read: doi.org/10.1007/s115...

Fibroblast Has2 limits acute heart failure following myocardial infarction in male mice Changes to the extracellular matrix support acute wound healing following myocardial infarction. Fibroblasts regulate the composition of the extracellular matrix, in part, by secreting hyaluronan.…

#Heart Failure and #Sexdifferences: in a mouse model of non-reperfused #myocardial #infarction, male mice with #fibroblast-specific knockout of #hyaluronan synthase 2 (#Has2), had exacerbated heart failure vs. wildtype mice; a difference not apparent in female mice.

Sertraline exposure during development may impact post‐myocardial infarction survival in adult mice The impact of developmental sertraline exposure on post-myocardial infarction (MI) outcomes.

Developmental exposure to the #antidepressant #sertraline is shown to
induce sex-specific #cardiac structural and functional changes in a mouse model of #myocardial #infarction.
doi.org/10.14814/phy...
#Cardiovascular

Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction | NEJM The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction (LVEF) is unclear. We conducted a meta-analysis at the individual-patient le...

Beta-Blockers after #Myocardial #Infarction with Normal Ejection Fraction www.nejm.org/doi/10.1056/... #hvhebron #cardio @nejm.org

#Research by Hiago B. Nunes et al. investigated optimizing embedding spaces for recurrence-based analysis of multivariate #cardiac signals, focusing on #myocardial infarction detection from 12-lead ECG data 🫀 💻

📜 Read the study here: www.jprecisionmedicine.org/article/S305...

Cardiovascular Benefit Seen With Tirzepatide in Head-to-Head Trial SURPASS-CVOT evaluated the efficacy and safety of tirzepatide compared with dulaglutide in adults with T2D and a confirmed ASCVD.

#Tirzepatide was noninferior to dulaglutide for the primary endpoint of time to first occurrence of death from #cardiovascular causes, #myocardial infarction, or #stroke.

Read More: https://bit.ly/4gZpXvP

ZBP1 drives #Cardiomyocyte #PANoptosis via the ZBP1/RIPK3/CASP6/CASP8 complex, with cardiomyocyte-specific Zbp1 deficiency reducing #Myocardial I/R injury, while the small molecule MSB targets ZBP1 to mitigate damage. @fudan-university.bsky.social

#STTT: doi.org/10.1038/s413...

Study finds #NF1 is associated with a 2.5% 10‐year risk for #myocardial #infarction at age 50, suggesting that NF1 is a major risk factor for myocardial infarction. bit.ly/42J9jdI #coronaryarterydisease

This study uncovers that #AtrialNatriureticPeptide (ANP) regulates Zn2⁺ #homeostasis during #Reperfusion injury by inhibiting ZnT8 through the phosphoinositide 3-kinase (#PI3K) signaling pathway, thereby reducing #Myocardial I/R injury. #medsky
Read:
link.springer.com/article/10.1...

Myocardial infarction may be an infectious disease A pioneering study by researchers from Finland and the UK has demonstrated for the first time that myocardial infarction may be an infectious disease. This discovery challenges the conventional…

#Myocardial #infarction may be an infectious #disease ...

| #infection | #pathogenesis | #vaccine | #plaques | #biofilm | #virus | #bacteria | Via eurekalert .org

Mast Cells Contribute to Pressure Overload-Induced Myocardial Hypertrophy by Upregulating TRPV4 via Histamine: Role of Ca2+/ CnA/NFATc3 Signaling Pathway

This study identifies that the upregulation of #TRPV4, driven by #Histamine from #Cardiac #MastCells, is crucial in pressure overload-induced #myocardial #hypertrophy through the Ca2+-induced activation of the CnA/NFATc3 signaling pathway. #medsky

Read: link.springer.com/article/10.1...

Possible lore doodle

Medley has been [REDACTED]
#ARR1V3L #SouthpawStylist #sketch #digitalart #oc #myocardial #ocsky

Panel 1 Friend: Are you all secretly furries? Panel 2 Me: I mean, the fursonas look cool, but- Panel 3 Friend: Okay. Get one. Panel 4 ... Panel 5 Me: Quite the persuasive argument!

Inspired by a real convo with a friend...

(Clearer dialogue in the alt text)

#makeaterriblecomicday2025 #art #oc #myocardial #othersoc #comic

New in JMCC Plus: This study presents a multidimensional analysis to investigate culture-induced alterations in living #myocardial slices, demonstrating structural integrity despite changes to slices’ functional and #molecular profiles

Read more here! www.sciencedirect.com/science/arti...

Involvement of connexin 43 in myocardial ischemia–reperfusion injury - Cell and Tissue Research Connexin 43 (Cx43) is the principal connexin isoform expressed in the ventricular myocardium, where it is critically involved in the pathophysiology of cardiac ischemia–reperfusion injury. Its functio...

Involvement of connexin 43 in #myocardial #ischemia-reperfusion injury link.springer.com/article/10.1... #hvhebron #cardio

New data that #pericyte contraction due to increased compression (pressure), such as occurs during acute #myocardial #infarction, depends on TRPM channels, #TRPM4 and #TRPM7. TRPM4 inhibition reduced infarct size in a mouse MI model.
doi.org/10.14814/phy...

Happy pride month everyone! With love from my ocs Quill & Ophelia ♡
#happypride2025 #prideflags #myocardial #procreate

This study demonstrated that #AtrialNatriureticPeptide (ANP) mitigates #myocardial #IschemiaReperfusion (I/R) injury by downregulating Zn2⁺ transporter 8 (ZnT8) through the #PI3K signalling pathway and modulating Zn2⁺ homeostasis.

Read more: link.springer.com/article/10.1...

Sketching more of my main OCs gives me so much joy now their stories finally got finalized.

#myocardial #writerlife #artist #dailylife

By the way, her story is not just for me to tell but to my Father who gives every reason to create out of love.

#writerlife #worldbuilding #myocardial #christianfantasy