The p97 ATPase and its adaptor UBXD8 maintain #peroxisome pools by preventing #pexophagy. From Iris Montes, Malavika Raman @maliramanlab.bsky.social and colleagues: rupress.org/jcb/article/...
📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#GRC
We are excited that our paper on peroxisomal control of viral injury and long COVID @science is selected for the #STATMadness @statnews.com Small Organelle #Peroxisome Big Roles! Help us to go to round 2!🙏 statnews.com/feature/stat-madness/bracket-voting-now-open
The p97 ATPase and its adaptor UBXD8 maintain #peroxisome pools by preventing #pexophagy. From Iris Montes, Malavika Raman @maliramanlab.bsky.social and colleagues: rupress.org/jcb/article/...
📕 Part of #Autophagy 2026 👉 rupress.org/jcb/collecti...
#KSAutophagy26
In vivo mapping of #peroxisome dynamics and #pexophagy using PO-TRG and CA-PO-TRG reporter mice. New study from Yue Xiong, Weihua Gao, Zelai Wu, Xiukui Gao, Qiming Sun (Zhejiang University) and colleagues: rupress.org/jcb/article/...
#Organelles #Technology
Impact of peroxisomal biogenesis protein PEX11a deficiency on cardiomyocyte structure and cardiac function in a mouse model. #cardiomyocyte #peroxisome #ischemia #oxidativestress #lipidmetabolism #MALDIMSI
www.mdpi.com/2073-4409/15...
Reevaluating the roles of PPARs and nuclear receptors in human #peroxisome biology. New Viewpoint from Fred Mast (@fredmast.bsky.social), Richard Rachubinski, and John Aitchison @seattlechildrens.org: rupress.org/jcb/article/...
#Organelles #Development #Metabolism #CellSignaling #Peroxisomes
Hongli Li, Marc Fransen et al. identify PEX14 as a key link between optineurin and the autophagic machinery in #pexophagy, the selective degradation of #peroxisomes. This discovery advances our understanding of #peroxisome clearance and disease. rupress.org/jcb/article/...
#Autophagy #Organelles
In @jcb.org, Hongli Li, Marc Fransen et al. identify PEX14 as a key link between optineurin and the autophagic machinery in #pexophagy, the selective degradation of #peroxisomes. This discovery advances our understanding of #peroxisome clearance and disease. rupress.org/jcb/article/...
#Autophagy
"That's one small step for [a] man, one giant leap for #peroxisome research" Yesterday I finally submitted my PhD thesis @uni-wuerzburg.de ! Thanks to everyone involved from the @warscheidlab.bsky.social and others and very much looking forward to the defense 🛡⚔️ #proteomics #TeamMassSpec #PhDlife
Our latest bioRxiv preprint on the molecular mechanisms underlying #Pex8's essential role in Peroxisomal Protein Import
A huge thanks to all authors and collaborators for their crucial support! 🙏
doi.org/10.1101/2025...
#Peroxisome #ProteinImport #CryoEM #XLMS #SAXS #Crystallography #AlphaFold3
The p97 ATPase and its adaptor UBXD8 maintain #peroxisome pools by preventing #pexophagy, say Iris Montes, Malavika Raman @maliramanlab.bsky.social @tufts.edu and colleagues: rupress.org/jcb/article/...
@joshilaboratory.bsky.social
#Biochemistry #Organelles
Borisyuk, Kaganovich, Amen et al. (EPFL, @unisouthampton.bsky.social) show that PKC promotes peroxisome-ER interactions and #peroxisome formation. rupress.org/jcb/article/...
▶️ See video summary of the study by Howman: youtu.be/HAYOi4GU31E
In @jcb.org, Montes et al. @maliramanlab.bsky.social @tufts.edu find the p97 ATPase and its adaptor UBXD8 maintain #peroxisome abundance by suppressing #pexophagy. p97-UBXD8 degrade ubiquitylated peroxisomal proteins to bypass recognition by #autophagy receptors. rupress.org/jcb/article/...
Montes et al. @maliramanlab.bsky.social @tufts.edu find the p97 ATPase and its adaptor UBXD8 maintain #peroxisome abundance by suppressing #pexophagy. p97-UBXD8 degrade ubiquitylated peroxisomal proteins to bypass recognition by #autophagy receptors. rupress.org/jcb/article/...
#Biochemistry
Protein Kinase C promotes #peroxisome biogenesis & peroxisome–endoplasmic reticulum interaction, say Anya Borisyuk, Daniel Kaganovich, Triana Amen (EPFL, @unisouthampton.bsky.social) et al: rupress.org/jcb/article/...
▶️ Charlotte Howman provides a video summary: youtu.be/HAYOi4GU31E
#ER_literature
Borisyuk, Kaganovich, Amen et al. (EPFL, @unisouthampton.bsky.social) show that PKC promotes peroxisome-ER interactions and #peroxisome formation. rupress.org/jcb/article/...
▶️ See video summary of the study by Howman: youtu.be/HAYOi4GU31E
#ER_literature
In @jcb.org, Borisyuk, Kaganovich, Amen et al. (EPFL, @unisouthampton.bsky.social) show that PKC promotes peroxisome-ER interactions and #peroxisome formation. rupress.org/jcb/article/...
▶️ See video summary of the study by Howman: youtu.be/HAYOi4GU31E
#ER_literature
👋Our June issue's out!
Cover: #Ferroptosis hotspots
👉🏼Editorial on #microscopy reporting
👉🏼Review on #mitochondria membrane
🔬 #cholesterol transport #neutrophils #exosomes #CellDeath #RNA #DNArepair #BreastCancer #ExtracellularVesicles #peroxisome proteins & more!
www.nature.com/ncb/volumes/...
Learn all things #peroxisome #research at the EMBO Workshop "Celebrating 70 years of peroxisome research" in Sant Feliu de Guíxols, Spain, 2–6 September 2025.
Registration deadline: 22 June 2025
meetings.embo.org/event/25-per...
#EMBOperoxisomes #EMBOevents 🧪
A new study from our CoE finds that stem cells can control whether they self-renew or differentiate by localizing certain metabolic reactions differently www.helsinki.fi/en/faculty-b... @helsinki.fi @helsinki-biotech.bsky.social #stemcell #metabolism #peroxisome
ZBTB17/MIZ1 promotes #peroxisome biogenesis by transcriptional regulation of PEX13, say Hongqin Liu, Xi Chen, Min Zhuang (ShanghaiTech University) and colleagues: rupress.org/jcb/article/...
#Biochemistry #Organelles
Visualize global & tissue-specific #Pexophagy in #Drosophila 🤠
Pexo-QC
Pexo-Keima
SKL signal for translocation to #Peroxisome matrix
@drbaronefg.bsky.social l #OpenBiology 2025
royalsocietypublishing.org/doi/10.1098/...
Read the excellent🧵from 1st auth Dr. Barone 👇
bsky.app/profile/drba...
#Dietary Restriction and AMPK Increase #Lifespan via Mitochondrial Network and #Peroxisome Remodeling www.cell.com/cell-metabolism/fulltext...
