Boston-based #biotech #AvalynPharma is the latest to hop on the #IPO train, filing to list on the #Nasdaq and raise funds for late-stage clinical development of its inhaled therapies for #pulmonaryfibrosis (PF).
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#pulmonaryFibrosis
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#LKB1 loss in alveolar epithelial cells reduces #autophagy, induces #EMT, and drives #PulmonaryFibrosis via epithelial–fibroblast crosstalk, highlighting CAB39L‑LKB1 signaling as a potential therapeutic target in IPF. @unisouthampton.bsky.social
#OpenAccess: doi.org/10.1016/j.ge...
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What is IPF? Part 2 of 2
Shortness of breath and a dry cough aren’t always just aging. Learn the signs of Idiopathic Pulmonary Fibrosis and why early diagnosis matters.
#IPF #PulmonaryFibrosis #LungHealth #Pulmonology #RespiratoryHealth #MedicalEducation #BreathingMatters
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What is IPF? Part 1 of 2.
Shortness of breath isn’t always just aging. Learn the signs of Idiopathic Pulmonary Fibrosis. Early diagnosis matters.
#IPF #PulmonaryFibrosis #LungHealth #Pulmonology #RespiratoryHealth #MedicalEducation
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Shortness of breath that keeps getting worse isn’t always just aging.
A persistent dry cough, unexplained weight loss, or fingertip changes called clubbing can be signs of lung scarring.
Talk to a pulmonologist if this sounds familiar.
#IPF #PulmonaryFibrosis #LungHealth
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Suppression of miR-17 Alleviates Acute Respiratory Distress-associated Lung Fibrosis by Regulating Mfn2
This study shows that #miR-17 inhibition alleviates ARDS-associated #PulmonaryFibrosis in mice by reducing #LungInjury, #Collagen deposition, and #Inflammation, while promoting #Mitochondrial #Autophagy through Mfn2 regulation. #medsky
To read: doi.org/10.1007/s115...
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The #highschool #sciencefair was awesome, all of these kids are 17-18 years old, one is repurposing #pulmonaryfibrosis drugs to help treat #Alzheimers among other amazing research
And #Obama had come when he was POTUS. Can you imagine Trump at a science fair? 🤣 there was a lot of calculus
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Senator Elissa Slotkin has acknowledged my message supporting the SOAR Act! This legislation is critical for PF & ILD patients who need supplemental oxygen.
Add your voice today 👇
https://www.pulmonaryfibrosis.org/soar-act
#SOARAct #PatientAdvocacy #PulmonaryFibrosis
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I’ve sent my message supporting the SOAR Act to improve access to supplemental oxygen for PF & ILD patients. This is so important—add your voice today!
👉 https://www.pulmonaryfibrosis.org/soar-act
#SOARAct #PatientAdvocacy #PulmonaryFibrosis
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#RareDiseaseDay advocacy for #PulmonaryFibrosis: Wed these lovely people and I go to Capitol Hill!!
Big thanks to the offices of House Representatives Greg Murphy, Pat Harrigan, Alma Adams, and David Rouzer. Our goals:
✅️COSPONSOR the SOAR Act
✅️KEEP report language for Pulmonary Fibrosis research
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Rare Disease Day is February 28.
#PH is often associated with other rare diseases such as #scleroderma, #HHT, idiopathic #pulmonaryfibrosis, #sicklecell disease and #lupus.
Raising awareness, improving diagnosis and ensuring access to care can save lives. Learn more: buff.ly/8TU8sC5
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Link to donate: teamtelomere.networkforgood.com/projects/294...
#TeamTelomere #26for26 #ResearchSeason #RareDiseaseMonth #RareDisease #DyskeratosisCongenita #TelomereBiologyDisorders #PulmonaryFibrosis #LungTransplant #HopeThroughResearch #AdvocacyInAction #ResearchMatters
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Revising the model for #SurfactantProteinC maturation: doi.org/10.1016/j.jb... #PulmonaryFibrosis #CellBiology #ProteinTrafficking #AT2Cells #LungDisease #TranslationalScience
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🫁🌿 Can immune regulation slow pulmonary fibrosis?
A CJNM review shows how natural products modulate immune cells and cytokines to intervene in fibrosis progression.
📘Read on ScienceDirect :
www.sciencedirect.com/science/arti...
#CJNM #PulmonaryFibrosis #NaturalProducts
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🩸Today's question! See the answer and explanation on the next slide.
#TERC #TelomereDisorders #IBMFS #BoneMarrowFailure #PulmonaryFibrosis #Hematology #RareDiseases #HEMEHUB
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🩸More insights on long-term complications and surveillance in Inherited Bone Marrow Failure Syndromes
#IBMFS #DyskeratosisCongenita #HCT #StemCellTransplant #PulmonaryFibrosis #PostHCT #IronOverload #Vasculopathy #Hematology #RareDiseases #HEMEHUB
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#S1pr3 drives #PulmonaryFibrosis by promoting #macrophage M2 polarization via the PI3K/Akt‑Stat3 pathway, while S1pr3 inhibitors showed protective effects in mouse models, highlighting S1pr3 as a promising therapeutic target.
#OpenAccess: doi.org/10.1016/j.ge...
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🫁 Can Tracheloside (TCL) slow pulmonary fibrosis?
A #CJNM study shows TCL activates AMPK, suppresses fibroblast differentiation, and reduces oxidative stress—a potential lead for IPF treatment. 🔬
🔗 Read it on ScienceDirect
#PulmonaryFibrosis #AMPK #NaturalProducts #CJNM
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Brainomix's AI imaging tech will serve as a co-primary endpoint in Boehringer Ingelheim's Phase 3 DROP-FPF trial for pulmonary fibrosis—a first for ILD studies. #AI #News #ClinicalTrials #PulmonaryFibrosis #MedicalImaging #Brainomix
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Brainomix's AI imaging tech will serve as a co-primary endpoint in Boehringer Ingelheim's Phase 3 DROP-FPF trial for pulmonary fibrosis—a first for ILD studies. #AI #News #ClinicalTrials #PulmonaryFibrosis #MedicalImaging #Brainomix
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Are you prescribing Nerandomilast for your pulmonary fibrosis patients yet? Should you be?!
Listen to today's episode on the FIBRONEER-IPF trial to learn more: www.pulmpeeps.com/2026/01/13/1...
Infographic 👇
#pulmonology
#pulmonarymedicine
#medicaleducation
#FOAMed
#pulmonaryfibrosis
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#PRDX4 disrupts #PTEN homodimerization to activate AKT/NF‑κB signaling, driving #alveolar #macrophage activation and fibrosis, and emerges as a novel upstream regulator of PTEN and promising target for #PulmonaryFibrosis and #silicosis.
#OpenAccess in #STTT: doi.org/10.1038/s413...
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The project “Modification of the #vimentin filament network regulating #cellmechanics and #matrixremodeling in #3Dpulmonaryfibrosismodels” has been funded in OPUS 29 NCN. Congratulations to Joanna Zemla, who will lead this project. #IFJPAN. #NCN #OPUS29 #PulmonaryFibrosis
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PPF is a recently adopted term that encompasses interstitial lung diseases with a progressive fibrotic phenotype, other than idiopathic PF.
Understand its epidemiology, prognosis, and the current status of antifibrotic treatments.
👉 buff.ly/y7e4bn1
#PulmonaryFibrosis
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Blocking S1PR3 reduces bleomycin-induced pulmonary fibrosis by inhibiting macrophage M2 polarization—a major inflammatory driver in tissue scarring.
#PulmonaryFibrosis #Macrophages #S1PR3 #InflammationBiology
www.sciencedirect.com/science/arti...
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#research call! ILFA has received funding for a VPR pilot for #lungfibrosis patients in 2026. We need a #study partner-please share with anyone you think would be interested. Deadline for expressions of interest is 9th of January. More info: ilfa.ie/blog/urgent-... #ipf #ppf #ild #pulmonaryfibrosis
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#NEWS: The @fda.gov has approved our new treatment for progressive pulmonary fibrosis (PPF) in adults. The approval provides hope to people living with this life-threatening condition.
Learn more here: go.boehringer.com/SYRTX
#LifeForward #PulmonaryFibrosis
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PULMONARY FIBROSIS (França) presenta nou recopilatori: "Nasal Nauseous Vomit Liquid Goregrind History Volume 4" #PulmonaryFibrosis #Goregrind #Noisegrind #BrutalDeathMetal #Grindcore #Desembre2025 #França #NouRecopilatori #Metall #Metal #MúsicaMetal
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#NEWS: China’s National Medical Products Administration (NMPA) has approved our new treatment for progressive #PulmonaryFibrosis (PPF). 🧪
In a field where milestones are scarce, today signals meaningful momentum for the PPF community.
Learn more: go.boehringer.com/ao0kp
#LifeForward
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