The functional role of #glial cells in the pathologic brain as reviewed by Alois #Alzheimer in 1910
Helmut Kettenmann, Hans Lassmann, Bilge Ugursu, Xianyuan Xiang #microglia #neuroinflammation
link.springer.com/article/10.1...
4-Dec-2025
researchers identify the #brain #enzyme that drives #nicotine #addiction and #smoking dependence
Researchers uncover how overlooked #glial cells regulate nicotine-dependent behavior, pointing toward future smoking cessation-related research
^^ #preclinical research on #rats still but […]
Drosophila juvenile brain labeled for astrocyte-like glia and ensheathing glia. Spatial organization of astrocyte-like glia (right) and ensheathing glia (left) subclasses. These two glial populations sculpt brain circuit architecture, with coordinated activities in mediating critical period experience-dependent connectivity remodeling. Together, these glial subclasses provide a cellular mechanism for synapse pruning in response to experience that shapes circuitry in development and can re-open plasticity at maturity. Image Creator: Vanessa Miller
A previous @plosbiology.org study showed that #synapse elimination in a #Drosophila brain circuit depends on #glial #serotonergic signaling. This new study shows that serotonin coordinates 2 distinct classes of #glia, with MMP-1 acting downstream of 5-HT2AR activation 🧪 plos.io/48oSY00
🔥 BlueSky trending hashtags (30m):
#glial #drosophila #synapse #glia #serotonergic #art #digitalart #transfur #transformation #tftuesday #tf #tfeveryday #furry #booksky #birds #vogels #pimpelmees #bluetit #soestdijk #opinião
🚀 BlueSky trending hashtags (15m):
#glial #drosophila #synapse #glia #serotonergic #art #digitalart #transfur #transformation #tftuesday #tf #tfeveryday #furry #booksky #birds #vogels #pimpelmees #bluetit #soestdijk #opinião
Drosophila juvenile brain labeled for astrocyte-like glia and ensheathing glia. Spatial organization of astrocyte-like glia (right) and ensheathing glia (left) subclasses. These two glial populations sculpt brain circuit architecture, with coordinated activities in mediating critical period experience-dependent connectivity remodeling. Together, these glial subclasses provide a cellular mechanism for synapse pruning in response to experience that shapes circuitry in development and can re-open plasticity at maturity. Image Creator: Vanessa Miller
A previous @plosbiology.org study showed that #synapse elimination in a #Drosophila brain circuit depends on #glial #serotonergic signaling. This new study shows that serotonin coordinates 2 distinct classes of #glia, with MMP-1 acting downstream of 5-HT2AR activation 🧪 plos.io/48oSY00
Drosophila juvenile brain labeled for astrocyte-like glia and ensheathing glia. Spatial organization of astrocyte-like glia (right) and ensheathing glia (left) subclasses. These two glial populations sculpt brain circuit architecture, with coordinated activities in mediating critical period experience-dependent connectivity remodeling. Together, these glial subclasses provide a cellular mechanism for synapse pruning in response to experience that shapes circuitry in development and can re-open plasticity at maturity. Image Creator: Vanessa Miller
A previous @plosbiology.org study showed that #synapse elimination in a #Drosophila brain circuit depends on #glial #serotonergic signaling. This new study shows that serotonin coordinates 2 distinct classes of #glia, with MMP-1 acting downstream of 5-HT2AR activation 🧪 plos.io/48oSY00
🧬 #CRISPR, #Glial reprogramming & #Inflammasome blockers 💥—new tools to rewire #Aging from within #Epigenetics, #NeuroRepair, #Longevity @mdpiopenaccess.bsky.social
💡 Explore 👉
doi.org/10.20944/pre...
On Thursday, November 6th, Cole Brashaw will present his Dissertation Defense: "Dissecting the molecular mechanisms of #glial migration and engulfment responses to axon injury in #Drosophila melanogaster" at 10am in Vollum's M1441. Cole is mentored by Dr Mary Logan. #OHSUResearch
4️⃣ Innovation
🧬 #CRISPR, #Glial reprogramming & #Inflammasome blockers 💥—new tools to rewire #Aging from within #Epigenetics, #NeuroRepair, #Longevity @mdpiopenaccess.bsky.social
💡 Explore 👉
doi.org/10.20944/pre... #FutureOfNeuroscience #RetweetScience
🔸Women showed higher levels of #synaptic biomarkers.
🔸Men showed higher levels of biomarkers linked to #neurodegeneration, #glial activation, and #vascular dysregulation.
🔸#CSF biomarkers are more indicative of #amyloid accumulation in the brain of women
#publichealth #ecology #health #glial #gerontology #agedcare #neurology #ecotoxicology #immunology #SDGs #geriatrics #agedcare #aging #ageing #oncology #etiology
Cadmium promotes
brain cancer (glioblastoma multiforme)
by inducing cytokine response
in astrocytes.
.
ascopubs.org/doi/abs/10.1...
I had a great time at the #Glial #Symposium of the @warsawgliacomm.bsky.social in Warsaw. Awesome presentations and excellent discussions with this emerging #glial community. I'm looking forward to the next endeavors and collaborations!
@szewczyklukasz.bsky.social
Submit an abstract for our 2nd @italianglianetwork.bsky.social
Symposium by Oct 10.
We want to see your cool #glial research!!!
The 2nd #IGN Symposium will be online on November 26 at 2 pm CET, and everybody can attend 😍 We will post the link to connect here: tinyurl.com/ye232mx9
#Cytokines ⚡, #Glial sparks🌩️, #Stress #Hormones 🌀—when one system flares, others follow! That’s why chronic #Pain echoes as mood swings or fading #Memory! #Neuroimmune #Biomedicine @mdpiopenaccess.bsky.social
👉 www.mdpi.com/2227-9059/13...
New study shows distinct #TET enzyme activities guide neural stem cell fate: 5hmC enables neuronal competence, while 5fC and 5caC are essential for #glial lineage. #neurons #stemcells ow.ly/9UX850WygWT
@einsteinmededu.bsky.social @isscr.org @gairdnerawards.bsky.social @sickkidsvs.bsky.social
Qkine human ciliary neurotrophic factor (CNTF) is animal origin-free, carrier-free and tag-free to ensure a homogenous cell population with exceptional lot-to-lot consistency.
View human CNTF and buy online > zurl.co/w0Wwv
#cytokines #glial #neuralstemcells
#PD≠just #Dopamine loss🎢 #Omics+ #AI map #Immune, #Gut & #Glial chaos🌐🧬Scrap one‑size‑fits‑all pills—build a #Biomarker‑driven, patient‑coded future🚀💡🤝 @mdpiopenaccess.bsky.social #Parkinsons #NeuroTwitter #PrecisionMedicine
Read & share! www.preprints.org/manuscript/2...
#Glial #phagocytosis for synapse and toxic proteins in #neurodegenerative diseases
Yeseong Choi & Won-Suk Chung
molecularneurodegeneration.biomedcentral.com/articles/10....
🪱 @fredhutch.bsky.social researchers created a gene-expression map of #glial cells in C. elegans. This completes the first molecular level atlas of the entire nervous system of a multicellular adult animal!
📰 Press release: bit.ly/3Tq87ap
🥼 Abstract: bit.ly/44QLzpw
#Glial cells promote #infection by #neurotropic #Influenza A viruses in vitro, etidiohnew.blogspot.com/2025/06/glia...
GLIA 2025 is just 20 days away! 🎉
We’re excited to reunite the world’s top #glial cell researchers in sunny Marseille 🌞
#GLIA2025 is more than a congress - it's a one-of-a-kind gathering. We can’t wait to see you all in person!
#MarseilleMagic #GliologistsTogether #NetworkGlia
Only 3 Days Left! 🚨
Join the world’s largest #glial cell congress — #GLIA2025 in Marseille 🇫🇷
🧠 8–11 July 2025
⏳ Regular registration ends 19 June!
👉 www.glia2025.eu/registration
#Neuroscience #MarseilleMagic #GliologistsTogether #NetworkGlia
Now published in the June issue @natneuro.nature.com
I am especially happy that the artwork my 4-year-old son created (with a little help) was chosen for the cover.
#Glial cells in diverse hues as paint splotches, CD8+ #Tcells in red, aberrant #myelin in purple.
Thanks @elisaflo.bsky.social & team!
Calling all #neuroscience, #biotech & #lifesciences companies!
Join us at #GLIA2025 – the world’s largest #glial cell meeting!
⚠️ Limited exhibition spots left!
📍Marseille | 8–11 July 2025
👥 1,200+ attendees
🤝 Sponsor & connect with top scientists
👉 glia2025.eu/sponsorship-exhibition
🚨 The #GLIA2025 Plenary Lineup is 🔥
7 top scientists, 1 big meeting in sunny 'Marseille ☀️🧠
🧠 Bruno Weber
🧠 Kelly Monk
🧠 Klaus-Armin Nave
🧠 Nathalie Rouach
🧠 Anna Molofsky
🧠 Bart J.L. Eggen
🧠 Maiken Nedergaard
July 8–11 — join us for cutting-edge glial science.
🔗 glia2025.eu
#Neuroscience #glial
These #Tregs appear to restrain #IFN gamma production & #inflammation (by regulating #IL-2 levels), inhibit immunocyte infiltration into the #parenchyma, restrain #glial cells in #hippocampus, regulate #hippocampal #neurogenesis, & promote short-term #memory!
First 🦋 post! Very excited to share our lab's latest work exploring the shared and divergent aspects of human astrocyte development and glioblastoma. This effort spans many fields from developmental #glial biology to #stem cells and #tumor biology. rdcu.be/d5ADz A 🧵
Key players in brain aging [via Allen Inst] 🧪🧠🧓⚕️
"The discoveries could pave the way for future therapies to slow or manage the #aging process in the #brain."
alleninstitute.org/news/key-pla...
#neuroscience #glial #cells #gene #expression #inflammation #hypothalamus #diet #nutients #homeostasis
