DNA methylation contributes to plant acclimation to naturally fluctuating light Plants in the natural environment experience continuous dynamic changes in light intensity. Here, we exposed Arabidopsis thaliana plants to naturally fluctuating light (FL) regimes alongside tradi...

#DNA #methylation contributes to plant #acclimation to naturally fluctuating #light

nph.onlinelibrary.wiley.com/doi/10.1111/...

#PlantScience @newphyt.bsky.social @jcellsci.bsky.social @methylation-mark.bsky.social @mpi-ie.bsky.social @epigeneticspod.bsky.social @epigenetichulk.bsky.social

Figure 1 Medrano et al (2026): Box-plots showing variation in average genome-wide DNA cytosine methylation (%) between ramets from the three study populations assigned to each of the three levels of herbivory treatment (control, insect and artificial herbivory). Each dot represents a ramet (N = 18, 27, and 18 for Spain, Italy and Poland, respectively). Lower and upper box boundaries are the 25th and 75th percentiles, respectively, line inside box the median, lower and upper error lines the 10th and 90th percentiles. Differences between the two herbivory levels and control undamaged plants were only statistically significant in CHH context

New publication: #Epigenomic response to #insect #herbivory in Lombardy #poplar: assessing geographic variation in #DNA #methylation changes, by @kjfverhoeven.bsky.social and others.
doi.org/10.1007/s112...

As usual, we've had a great time presenting our projects at the 7th Central German Meeting on #Bioinformatics - Mittelerde Meeting 2026 at @unihalle.bsky.social! 🧬⚕️🦠🌡️🔧🖥️
Thanks to the organizers and sponsors!
#epigenomics #diagnostics #methylation #ncRNA #adaption #Sugar #DataEngineering #metadata

ATCC Genome Portal's 2026 Q1 Release is live!
New #genomics #RNAseq #methylation #AMR data!
+80 human cell lines, +7 organoids, +206 bacteria, +26 viruses, +20 fungi, including 3 new MDR strains of Candida auris (Candidozyma auris). AGP now has >3600 DNA methylation profiles too! genomes.atcc.org

🧬 #BehindtheStudy:
Dr. Josh Mitteldorf summarizes his #research perspective #published in Volume 17, Issue 5, titled “Methylation clocks for evaluation of anti-aging interventions.”

🎥 www.youtube.com/watch?v=efgN...

#author #interview #aging #methylation #agingclocks #publishing #oa

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney

Carine Tisné gave an insightful talk at #Biochemistry2026. She talked about "Advances in the structural and functional understanding of m1A tRNA modification".

pubs.acs.org/doi/10.1021/...
#Biochemistry #RNA #tRNA #ChemSky #Biochemistry #Methylation
CC: @gdch.de

PNAS Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Leveraging #Polymorphism data as reliable proxy to map mutation patterns across 108 #Eukaryotic species www.pnas.org/doi/10.1073/... @bvoight28 #Methylation #CpG #GxEinteraction #TranslationalScience

Identical twins on trial: can DNA testing tell them apart? In a French criminal trial, conventional DNA analysis couldn’t distinguish between twin brothers, but emerging scientific methods could help in such cases.

Distinguishing #monozygotic #twins in a criminal trial: when conventional #DNA analysis is not enough
👉 whole #genome sequencing
👉 #mitochondrial DNA sequencing
👉 DNA #methylation analysis
www.nature.com/articles/d41...

🧬New from Li et al!
📄Epigenome-Wide Association Study of Blood Proteome in the #Atherosclerosis Risk in Communities Study
#EWAS #methylation
👉 bit.ly/4l5hgSu

A plant histone H3.3-specific amino acid safeguards the deposition of H3K36 methylation for proper development and stress responses Plant histone variant H3.3 uniquely carries T31 rather than the S31 found in animals. Li et al. demonstrate that T31 prevents plant-specific ATXR5/6-mediated H3K27me1 deposition, which would otherwise...

A plant #histone H3.3-specific #amino acid safeguards the deposition of H3K36 #methylation for proper #development and #stress responses

www.cell.com/developmenta...

#PlantScience #SciComm @cp-devcell.bsky.social @epigeneticspod.bsky.social @epigenometech.bsky.social @histone3.bsky.social

Researchers from Nanjing Forestry University and collaborating institutions report in Horticulture Research that DNA methylation dynamically regulates flowering time in diploid Cyclocarya paliurus.
#methylation analysis #floral buds
Details: doi.org/10.1093/hr/uhaf296

In #multiomics, #methylation sequencing isn’t a “nice to have.” It’s essential! Our Enzymatic #Methyl-Sequencing solution delivers accurate, high-resolution methylation #data to uncover gene regulation, disease mechanisms and treatment response.

Deepen #clinical insights: hubs.ly/Q041hHSp0

Syndex Bio announces:
🧬mcPCR (methyl‑copying PCR) platform @agbt.bsky.social
💵$15.5M #seedfunding
👥Gautam Kollu joins Board

#pressrelease www.syndex.bio/news/syndex-...

#AGBTGM26 #genomics #biotech #DNA #PCR #methylation #epigenetics #oncology #startup #boardappointment #messengersinscience

🧬 #BehindtheStudy:
Dr. Josh Mitteldorf summarizes his #research perspective #published in Volume 17, Issue 5, titled “Methylation clocks for evaluation of anti-aging interventions.”

🎥 www.youtube.com/watch?v=efgN...

#author #interview #aging #methylation #agingclocks #publishing #oa

From sample to insight: Streamlining analysis with the Illumina 5-base solution Discover how the Illumina 5-base solution and DRAGEN pipeline streamline genetic and epigenetic analysis with accurate methylation and variant insights.

Switch from painful #methylation protocols... #Illumina 5-Base plus #DRAGEN and Connected Multiomics make it so much easier. All from a single sample and single sequencing run. bit.ly/3MAr8qA
#genomics #multiomics #epigenetics

Focus on the most epigenetically informative regions with Novogene Reduced Representation Bisulfite Sequencing (RRBS). We enrich CpG islands via MspI, then bisulfite convert & sequence for high-resolution methylation profiling. #Epigenomics #Methylation https://bit.ly/4gG7CT1

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney

Map DNA methylation at single-base resolution across the whole genome with Novogene WGBS/EM-Seq. Detect 5mC, 5hmC and epigenetic changes with high coverage and library quality. #Epigenomics #Methylation #WGS #DNAmodifications https://bit.ly/401Wn1X

An Endocrinologist Appointment I had an endocrinologist appointment yesterday. It went well. The doctor was super nice and comforting. So I’m supposed to be taking my Synthroid at like 5am, hours before I eat anything or take an…

#adelusionalpredisposition

#mentalillness #hallucinations #voices #murmurs #radioDJ #whispers #niacin #vitaminc #psychNP #antipsychotics #endocrinologist #GP #prolactin #MTHFRgene #methylation #disability #invisibleillness #chronicinflammation #synthroid #pituitarygland #MRI

One of the fastest & precise #bisulfite conversion systems available - #SuperMethyl™ faster, cleaner methylation data
⏱️Convert DNA in under 10 mins
🎯>99.5% efficiency with excellent #methylation protection
🧬Works with gDNA, cfDNA, FFPE & NGS workflows
🔗 www.stratech.co.uk/ellisbio/

#biomarker

This review shows how #methylation modulates #microRNA biogenesis, stability, and function, influencing proliferation, #apoptosis, #tumorigenesis, and #HostPathogenInteractions as a flexible layer of gene regulation.

#OpenAccess: doi.org/10.1016/j.ge...

NKAPL is downregulated by promoter #methylation in #NSCLC and linked to poor prognosis, while its upregulation suppresses proliferation and #metastasis via NF-κB inhibition, highlighting NKAPL as a potential therapeutic target in #LungCancer.

#OpenAccess: doi.org/10.1016/j.ge...

Blood DNA markers associated with DKD progression paper screenshot

✅ 11 #epigenetic markers associated with progression of diabetic #kidney disease #DKD

✅ #methylation changes predictive of DKD progression

✅ methylation data+ clinical risk factors improved identification of risk
#RenalResearchNI @finndiane.bsky.social @niinasandholm.bsky.social

👀 rdcu.be/e0bUC

Always Tired? Fix Hormone-Related Fatigue With These Supplements If you’re doing “everything right” but still feel tired, foggy, bloated, or off, this episode breaks down what might be happening hormonally and what supplement support can actually help. Host Lisa Urbanski sits down with Carolyn Zaumeyer, a nurse practitioner specializing in hormone therapy, to explain science-backed supplements that support hormone function, thyroid health, energy, and overall well-being—without one-size-fits-all advice. In this episode, you’ll learn: ✨ Why symptoms matter more than “perfect” lab numbers ✨ DIM for healthier estrogen metabolism (women + men) ✨ Iodine and thyroid support—how to start safely ✨ Vitamin D: benefits, dosing, and why testing matters ✨ Probiotics for gut health, immunity, and nutrient absorption ✨ Methyl factors + B vitamins for energy, mood, and metabolism ✨ Why personalized supplement plans work better than trendy stacks

📣 New Podcast! "Always Tired? Fix Hormone-Related Fatigue With These Supplements" on @Spreaker #dim #energy #estrogen #fatigue #functionalmedicine #guthealth #hormonehealth #hormones #iodine #longevity #menshealth #metabolism #methylation #probiotics #supplements #testosterone #thyroid

This review explores sulfur-containing #biomolecules—from #MethionineMetabolism to H₂S signaling—highlighting their roles in #inflammation, #RedoxBalance, #methylation, and disease while outlining emerging therapeutic strategies. @pku1898.bsky.social

#STTT: doi.org/10.1038/s413...

New #OpenAccess work in #RESInsectMolecBio

Genome-wide & gene-specific #DNA #methylation across developmental stages in #Pogonomyrmex californicus: a socially polymorphic #ant
doi.org/10.1111/imb.70021

#Epigenetics
@sassanasgari.bsky.social @gulianusslab.bsky.social @wileyeco.bsky.social

aéPiot as a Strategic Asset: A Comprehensive Valuation Analysis. Understanding the True Value of Organic Growth at Scale. aéPiot as a Strategic Asset: A Comprehensive Valuation Analysis Understanding the True Value of Organic Growth at Scale Analysis Date: ...

better-experience.blogspot.com/2026/01/aepi...

#CORK #NORTH #WEST #DAIL #EIREANN #CONSTITUENCY
multi-search-tag-explorer.aepiot.com/advanced-sea...
#FRANS #MICHAEL #FRANZÉN
allgraph.ro/advanced-sea...
#DNA #METHYLATION
multi-search-tag-explorer.aepiot.ro/advanced-sea...
aepiot.ro

Client Challenge

#Research
Activated oligoadenylate synthetase-ribonuclease L pathway promotes endothelial #pyroptosis and impairs diabetic wound healing via thioredoxin-interacting protein #m6A #methylation doi.org/10.1186/s435...

#OAS_RNaseL #TXNIP #LPS #DiabeticWound

#MTHFR #Genetics #Methylation #HealthTips #BrainHealth #LongevityDiet #LongevityLifestyle #NutritionalScience #Folate #Supplements #biohack #biohacking #biohacker #biohackingsecrets #biohackers #biohacks #WellnessJourney